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Science Simplified!

                       JAI VIGNAN

All about Science - to remove misconceptions and encourage scientific temper

Communicating science to the common people

'To make  them see the world differently through the beautiful lense of  science'

Members: 22
Latest Activity: 3 hours ago

         WE LOVE SCIENCE HERE BECAUSE IT IS A MANY SPLENDOURED THING

     THIS  IS A WAR ZONE WHERE SCIENCE FIGHTS WITH NONSENSE AND WINS                                               

“The greatest enemy of knowledge is not ignorance, it is the illusion of knowledge.”             

                    "Being a scientist is a state of mind, not a profession!"

                  "Science, when it's done right, can yield amazing things".

         The Reach of Scientific Research From Labs to Laymen

The aim of science is not only to open a door to infinite knowledge and                                     wisdom but to set a limit to infinite error.

"Knowledge is a Superpower but the irony is you cannot get enough of it with ever increasing data base unless you try to keep up with it constantly and in the right way!" The best education comes from learning from people who know what they are exactly talking about.

Science is this glorious adventure into the unknown, the opportunity to discover things that nobody knew before. And that’s just an experience that’s not to be missed. But it’s also a motivated effort to try to help humankind. And maybe that’s just by increasing human knowledge—because that’s a way to make us a nobler species.

If you are scientifically literate the world looks very different to you.

We do science and science communication not because they are easy but because they are difficult!

“Science is not a subject you studied in school. It’s life. We 're brought into existence by it!"

 Links to some important articles :

1. Interactive science series...

a. how-to-do-research-and-write-research-papers-part 13

b. Some Qs people asked me on science and my replies to them...

Part 6part-10part-11part-12, part 14  ,  part- 8

part- 1part-2part-4part-5part-16part-17part-18 , part-19 , part-20

part-21 , part-22part-23part-24part-25part-26part-27 , part-28

part-29part-30part-31part-32part-33part-34part-35part-36part-37,

 part-38part-40part-41part-42part-43part-44part-45part-46part-47

Part 48 part49Critical thinking -part 50 , part -51part-52part-53

part-54part-55part-57part-58part-59part-60part-61part-62part-63

part 64, part-65part-66part-67part-68part 69part-70 part-71part-73 ...

.......306

BP variations during pregnancy part-72

who is responsible for the gender of  their children - a man or a woman -part-56

c. some-questions-people-asked-me-on-science-based-on-my-art-and-poems -part-7

d. science-s-rules-are-unyielding-they-will-not-be-bent-for-anybody-part-3-

e. debate-between-scientists-and-people-who-practice-and-propagate-pseudo-science - part -9

f. why astrology is pseudo-science part 15

g. How Science is demolishing patriarchal ideas - part-39

2. in-defence-of-mangalyaan-why-even-developing-countries-like-india need space research programmes

3. Science communication series:

a. science-communication - part 1

b. how-scienitsts-should-communicate-with-laymen - part 2

c. main-challenges-of-science-communication-and-how-to-overcome-them - part 3

d. the-importance-of-science-communication-through-art- part 4

e. why-science-communication-is-geting worse - part  5

f. why-science-journalism-is-not-taken-seriously-in-this-part-of-the-world - part 6

g. blogs-the-best-bet-to-communicate-science-by-scientists- part 7

h. why-it-is-difficult-for-scientists-to-debate-controversial-issues - part 8

i. science-writers-and-communicators-where-are-you - part 9

j. shooting-the-messengers-for-a-different-reason-for-conveying-the- part 10

k. why-is-science-journalism-different-from-other-forms-of-journalism - part 11

l.  golden-rules-of-science-communication- Part 12

m. science-writers-should-develop-a-broader-view-to-put-things-in-th - part 13

n. an-informed-patient-is-the-most-cooperative-one -part 14

o. the-risks-scientists-will-have-to-face-while-communicating-science - part 15

p. the-most-difficult-part-of-science-communication - part 16

q. clarity-on-who-you-are-writing-for-is-important-before-sitting-to write a science story - part 17

r. science-communicators-get-thick-skinned-to-communicate-science-without-any-bias - part 18

s. is-post-truth-another-name-for-science-communication-failure?

t. why-is-it-difficult-for-scientists-to-have-high-eqs

u. art-and-literature-as-effective-aids-in-science-communication-and teaching

v.* some-qs-people-asked-me-on-science communication-and-my-replies-to-them

 ** qs-people-asked-me-on-science-and-my-replies-to-them-part-173

w. why-motivated-perception-influences-your-understanding-of-science

x. science-communication-in-uncertain-times

y. sci-com: why-keep-a-dog-and-bark-yourself

z. How to deal with sci com dilemmas?

 A+. sci-com-what-makes-a-story-news-worthy-in-science

 B+. is-a-perfect-language-important-in-writing-science-stories

C+. sci-com-how-much-entertainment-is-too-much-while-communicating-sc

D+. sci-com-why-can-t-everybody-understand-science-in-the-same-way

E+. how-to-successfully-negotiate-the-science-communication-maze

4. Health related topics:

a. why-antibiotic-resistance-is-increasing-and-how-scientists-are-tr

b. what-might-happen-when-you-take-lots-of-medicines

c. know-your-cesarean-facts-ladies

d. right-facts-about-menstruation

e. answer-to-the-question-why-on-big-c

f. how-scientists-are-identifying-new-preventive-measures-and-cures-

g. what-if-little-creatures-high-jack-your-brain-and-try-to-control-

h. who-knows-better?

i. mycotoxicoses

j. immunotherapy

k. can-rust-from-old-drinking-water-pipes-cause-health-problems

l. pvc-and-cpvc-pipes-should-not-be-used-for-drinking-water-supply

m. melioidosis

n.vaccine-woes

o. desensitization-and-transplant-success-story

p. do-you-think-the-medicines-you-are-taking-are-perfectly-alright-then revisit your position!

q. swine-flu-the-difficlulties-we-still-face-while-tackling-the-outb

r. dump-this-useless-information-into-a-garbage-bin-if-you-really-care about evidence based medicine

s. don-t-ignore-these-head-injuries

t. the-detoxification-scam

u. allergic- agony-caused-by-caterpillars-and-moths

General science: 

a.why-do-water-bodies-suddenly-change-colour

b. don-t-knock-down-your-own-life-line

c. the-most-menacing-animal-in-the-world

d. how-exo-planets-are-detected

e. the-importance-of-earth-s-magnetic-field

f. saving-tigers-from-extinction-is-still-a-travail

g. the-importance-of-snakes-in-our-eco-systems

h. understanding-reverse-osmosis

i. the-importance-of-microbiomes

j. crispr-cas9-gene-editing-technique-a-boon-to-fixing-defective-gen

k. biomimicry-a-solution-to-some-of-our-problems

5. the-dilemmas-scientists-face

6. why-we-get-contradictory-reports-in-science

7. be-alert-pseudo-science-and-anti-science-are-on-prowl

8. science-will-answer-your-questions-and-solve-your-problems

9. how-science-debunks-baseless-beliefs

10. climate-science-and-its-relevance

11. the-road-to-a-healthy-life

12. relative-truth-about-gm-crops-and-foods

13. intuition-based-work-is-bad-science

14. how-science-explains-near-death-experiences

15. just-studies-are-different-from-thorough-scientific-research

16. lab-scientists-versus-internet-scientists

17. can-you-challenge-science?

18. the-myth-of-ritual-working

19.science-and-superstitions-how-rational-thinking-can-make-you-work-better

20. comets-are-not-harmful-or-bad-omens-so-enjoy-the-clestial-shows

21. explanation-of-mysterious-lights-during-earthquakes

22. science-can-tell-what-constitutes-the-beauty-of-a-rose

23. what-lessons-can-science-learn-from-tragedies-like-these

24. the-specific-traits-of-a-scientific-mind

25. science-and-the-paranormal

26. are-these-inventions-and-discoveries-really-accidental-and-intuitive like the journalists say?

27. how-the-brain-of-a-polymath-copes-with-all-the-things-it-does

28. how-to-make-scientific-research-in-india-a-success-story

29. getting-rid-of-plastic-the-natural-way

30. why-some-interesting-things-happen-in-nature

31. real-life-stories-that-proves-how-science-helps-you

32. Science and trust series:

a. how-to-trust-science-stories-a-guide-for-common-man

b. trust-in-science-what-makes-people-waver

c. standing-up-for-science-showing-reasons-why-science-should-be-trusted

You will find the entire list of discussions here: http://kkartlab.in/group/some-science/forum

( Please go through the comments section below to find scientific research  reports posted on a daily basis and watch videos based on science)

Get interactive...

Please contact us if you want us to add any information or scientific explanation on any topic that interests you. We will try our level best to give you the right information.

Our mail ID: kkartlabin@gmail.com

Discussion Forum

What is a three body problem?

Started by Dr. Krishna Kumari Challa. Last reply by Dr. Krishna Kumari Challa 3 hours ago. 1 Reply

Q: What is a three body problem?Krishna: I don't know about  science fiction or movies that are made based on the theme, but I will tell you what it is based on science.  Systems with two objects…Continue

Your Biological Age Can Be Different From Your Actual (Chronological)Age!

Started by Dr. Krishna Kumari Challa. Last reply by Dr. Krishna Kumari Challa 6 hours ago. 6 Replies

Recently I have seen an old lady teasing an young girl who became breathless after climbing up a few steps.  "Look I am 78. But still I can climb steps with ease. I can go anywhere I want without any…Continue

How Soil Microorganisms Can Combat Desertification

Started by Dr. Krishna Kumari Challa. Last reply by Dr. Krishna Kumari Challa 7 hours ago. 1 Reply

 Soil Microbiology is the specialized subject I studied during my Post…Continue

DNA can be considered as a natural flame retardant and suppressant

Started by Dr. Krishna Kumari Challa. Last reply by Dr. Krishna Kumari Challa yesterday. 1 Reply

Q: Is DNA fire-proof?Krishna: Research has shown that DNA is flame retardant (1). Yes, DNA can be considered as a natural flame retardant and suppressant.NORMALLY, COTTON FABRICS are highly…Continue

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You need to be a member of Science Simplified! to add comments!

Comment by Dr. Krishna Kumari Challa on September 1, 2022 at 9:37am

Researchers find spaceflight may be associated with DNA mutations, increased risk of heart disease and cancer

Astronauts are at higher risk for developing mutations—possibly linked to spaceflight—that can increase the risk of developing cancer and heart disease during their lifetimes, according to a first-of-its kind study from the Icahn School of Medicine at Mount Sinai.



A team of researchers collected blood samples from National Aeronautics and Space Administration (NASA) astronauts who flew space shuttle missions between 1998 and 2001. They discovered DNA mutations, known as soamtic mutations, in the blood-forming system ( hematopoietic stem cells)  in all 14 astronauts studied.

Their findings, published in the August issue of Communications Biology, suggest that spaceflight could be associated with these mutations and emphasize the importance of ongoing blood screening of astronauts throughout their careers and during their retirement to monitor their health.

Somatic mutations are mutations that occur after a person is conceived and in cells other than sperm or egg cells, meaning they cannot be passed on to offspring. The mutations identified in this study were characterized by the overrepresentation of blood cells derived from a single clone, a process called clonal hematopoiesis (CH).

Such mutations are frequently caused by environmental factors, such as exposure to ultraviolet radiation or certain chemicals, and may be a result of cancer chemo- or radiotherapy. There are few signs or symptoms associated with CH; most patients are identified after genetic testing of their blood for other diseases. Although CH is not necessarily an indicator of disease, it is associated with a higher risk for cardiovascular disease and blood cancer.

Astronauts work in an extreme environment where many factors can result in somatic mutations, most importantly space radiation, which means there is a risk that these mutations could develop into clonal hematopoiesis. Given the growing interest in both commercial spaceflights and deep space exploration, and the potential health risks of exposure to various harmful factors that are associated with repeated or long-duration exploration space missions.

 Agnieszka Brojakowska et al, Retrospective analysis of somatic mutations and clonal hematopoiesis in astronauts, Communications Biology (2022). DOI: 10.1038/s42003-022-03777-z

Comment by Dr. Krishna Kumari Challa on September 1, 2022 at 9:29am

New research in mice offers clues into how the brain processes sensory information from internal organs

Most of us think little of why we feel pleasantly full after eating a big holiday meal, why we start to cough after accidentally inhaling campfire smoke, or why we are hit with sudden nausea after ingesting something toxic. However, such sensations are crucial for survival: they tell us what our bodies need at any given moment so that we can quickly adjust our behavior.

Yet historically, very little research has been devoted to understanding these basic bodily sensations—also known as internal senses—that are generated when the brain receives and interprets input from internal organs.

Now, a team led by researchers at Harvard Medical School has made new strides in understanding the basic biology of internal organ sensing, which involves a complicated cascade of communication between cells inside the body.

In a study conducted in mice and published Aug. 31 in Nature, the team used high-resolution imaging to reveal spatial maps of how neurons in the brain stem respond to feedback from internal organs.

They found that feedback from different organs activates discrete clusters of neurons, regardless of whether this information is mechanical or chemical in nature—and these groups of neurons representing different organs are topographically organized in the brain stem. Moreover, they discovered that inhibition within the brain plays a key role in helping neurons selectively respond to organs.

The research is only a first step in elucidating how internal organs communicate with the brain. However, if the findings are confirmed in other species, including humans, they could help scientists develop better therapeutic strategies for diseases such as eating disorders, overactive bladder, diabetes, pulmonary disorders, and hypertension that arise when internal sensing goes awry.

Stephen Liberles, A brainstem map for visceral sensations, Nature (2022). DOI: 10.1038/s41586-022-05139-5www.nature.com/articles/s41586-022-05139-5

Comment by Dr. Krishna Kumari Challa on August 31, 2022 at 8:24am

Living in timber cities could avoid emissions, without using farmla...

Housing a growing population in homes made out of wood instead of conventional steel and concrete could avoid more than 100 billion tons of emissions of the greenhouse gas CO2 until 2100, a new study by the Potsdam Institute for Climate Impact Research shows. These are about 10% of the remaining carbon budget for the 2°C climate target. Besides the harvest from natural forests, newly established timber plantations are required for supplying construction wood. While this does not interfere with food production, a loss of biodiversity may occur if not carefully managed, according to the scientists. The study is the first to analyze the impacts of a large-scale transition to timber cities on land use, land-use change emissions, and long-term carbon storage in harvested wood products.

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Researchers reveal how salt may play into climate warming

A team of Skoltech researchers has published a series of three papers dealing with various aspects of how salt from the ocean water and other salts penetrate into frozen soil that contains gas hydrates—icelike crystals composed of water and gas, mostly methane. This so-called salt migration affects the rate at which permafrost melts as global warming advances. Taking that process into account is therefore necessary for accurate climate change modeling. The research findings are reported in papers dated June 27 and July 9 in the journal Geosciences, and in the July 5 paper in Energy & Fuels.

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Shape of coronavirus affects its transmission, study finds

Since the start of the COVID-19 pandemic, images of the coronavirus, SARS-CoV-2, have been seared in our minds. But the way we picture the virus, typically as a sphere with spikes, is not strictly accurate. Microscope images of infected tissues have revealed that coronavirus particles are actually ellipsoidal, displaying a wide variety of squashed and elongated shapes.

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Compound found in trees has potential to kill drug-resistant bacteria

University of Portsmouth researchers have found a naturally occurring compound, known as hydroquinine, has bacterial killing activity against several microorganisms.

Comment by Dr. Krishna Kumari Challa on August 31, 2022 at 8:19am

Breakthrough results in developing an oral insulin tablet

A team of researchers working on developing oral insulin tablets as a replacement for daily insulin injections have made a game-changing discovery.

Researchers have discovered that insulin from the latest version of their oral tablets is absorbed by rats in the same way that injected insulin is.

These exciting results show that scientists are on the right track in developing an insulin formulation that will no longer need to be injected before every meal, improving the quality of life, as well as mental health, of more than nine million type 1 diabetics around the world.

Researchers  are now seeing nearly 100 percent of the insulin from their tablets go straight into the liver. In previous attempts to develop a drinkable insulin, most of the insulin would accumulate in the stomach.

Even after two hours of delivery, researchers did not find any insulin in the stomachs of the rats they tested now. It was all in the liver and this is the ideal target for insulin—it's really what they wanted to see.

The team developed a different kind of tablet that isn't made for swallowing, but instead dissolves when placed between the gum and cheek.

This method makes use of the thin membrane found within the lining of the inner cheek and back of the lips (also known as the buccal mucosa). It delivered all the insulin to the liver without wasting or decomposing any insulin along the way.

Similar to the rapid-acting insulin injection, this new oral delivery tablet absorbs after half an hour and can last for about two to four hours long.

Now human trials are awaited. 

Yigong Guo et al, Production of high loading insulin nanoparticles suitable for oral delivery by spray drying and freeze drying techniques, Scientific Reports (2022). DOI: 10.1038/s41598-022-13092-6

Comment by Dr. Krishna Kumari Challa on August 31, 2022 at 8:03am

Khufu branch of Nile River once flowed close enough to Giza to carry the stones needed to build the pyramids

A team of researchers  has found evidence that shows the Khufu branch of the Nile River once ran so close to Giza that it could have been used to carry the stones that were used to build the famous pyramids. In their paper published in Proceedings of the National Academy of Sciences, the group describes their study of fossilized pollen grains found in the sediments around Giza and what it showed them about the history of the Khufu branch.

In their work, the researchers obtained core sediment samples that have been collected from several sites in and around Giza over the years and then took a close look at the fossilized pollen grains trapped in them for thousands of years.

By combining results from prior studies that involved studying the  surrounding the pyramids, they found that they were able to reconstruct the history of the Khufu branch as it flowed and ebbed in the area over the prior 8,000 years. Then, looking at the timeline and flow of the branch, they found its levels were high enough that it reached nearly all the way to Giza—7 kilometers from the Nile—during the times when three of the major pyramids (Menkaure, Khafre and Khufu) were built—approximately 4,000 years ago.

The researchers note that the pollen grain fossils they found were mostly from flowering grasses like the ones that line the Nile River today. They also found evidence of a few marsh plants, which typically grow on the edges of lakes—and that showed that the Khufu branch remained at high levels in the area long enough for nature to consider it permanent.

The researchers also found that not long after the reign of King Tutankhamun, levels of the branch began to drop, leading to a much more arid environment. Other studies of bones and teeth from mummies of the time also showed the area becoming much drier. The researchers suggest that others using the same techniques could learn more about how changing river flow impacted other ancient civilizations.

 Hader Sheisha et al, Nile waterscapes facilitated the construction of the Giza pyramids during the 3rd millennium BCE, Proceedings of the National Academy of Sciences (2022). DOI: 10.1073/pnas.2202530119

Comment by Dr. Krishna Kumari Challa on August 30, 2022 at 12:28pm

Mars' Moon Phobos Eclipses the Sun, as Seen by Curiosity

This video clip shows the larger of the two moons of Mars, Phobos, passing directly in front of the sun, in an eclipse photographed by NASA's Mars rover Curiosity.

Comment by Dr. Krishna Kumari Challa on August 30, 2022 at 11:42am

OPEN Access: The US has ruled all taxpayer-funded research must be free to read.

Last week, the United States announced an updated policy guidance on open access that will substantially expand public access to science not just in America, but worldwide.

As per the guidance, all US federal agencies must put in place policies and plans so anyone anywhere can immediately and freely access the peer-reviewed publications and data arising from research they fund.

The policies need to be in place by the end of 2025, according to President Biden’s White House Office of Science and Technology Policy (OSTP).

https://www.whitehouse.gov/ostp/news-updates/2022/08/25/breakthroug...

Comment by Dr. Krishna Kumari Challa on August 30, 2022 at 11:04am

During sprouting, seedlings rapidly elongate their stems to break through the covering soil to capture sunlight as fast as possible. Normally, the stem slows down its growth after exposure to sunlight. But the stem can lengthen rapidly again if the plant is competing with surrounding plants for sunlight, or in response to warm temperatures to increase distance between the hot ground and the plant's leaves. While both —canopy shade and warm temperatures—induce stem growth, they also reduce yield.

In this study, the scientists compared plants growing in canopy shade and warm temperatures at the same time—a condition that mimics high crop density and climate change. The scientists used the model plant Arabidopsis thaliana, as well as tomato and a close relative of tobacco, because they were interested to see if all three plant species were affected similarly by this environmental condition.

Across all three species, the team found that the plants grew extremely tall when simultaneously trying to avoid the shade created by neighboring plants and being exposed to warmer temperatures. On a molecular level, the researchers discovered that transcription factor PIF7, a protein that helps turn genes "on" and "off," was the dominant player driving the increased rapid growth. They also found that the growth hormone auxin increased when the crops detected neighboring plants, which fostered growth in response to simultaneous warmer temperatures. This synergistic PIF7-auxin pathway allowed the plants to respond to their environments and adapt to seek the best growing conditions.

A related transcription factor, PIF4, also stimulated stem elongation during warm temperatures. However, when shade and increased temperatures were combined, this factor no longer played an important role.

The researchers think that there is another player, yet to be discovered, that is boosting the effect of PIF7 and auxin. They hope to explore this unknown factor in future studies.

Global temperatures are increasing, so we need food crops that can thrive in these new conditions.

Scientists now  identified key factors that regulate plant growth during warm temperatures, which will help us to develop better-performing crops to feed future generations.

 PIF7 is a master regulator of thermomorphogenesis in shade, Nature Communications (2022). DOI: 10.1038/s41467-022-32585-6

Part 2

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Comment by Dr. Krishna Kumari Challa on August 30, 2022 at 11:02am

How light and temperature work together to affect plant growth

Plants lengthen and bend to secure access to sunlight. Despite observing this phenomenon for centuries, scientists do not fully understand it. Now, Salk scientists have discovered that two plant factors—the protein PIF7 and the growth hormone auxin—are the triggers that accelerate growth when plants are shaded by canopy and exposed to warm temperatures at the same time.

The findings, published in Nature Communications on August 29, 2022, will help scientists predict how plants will respond to climate change—and increase crop productivity despite the yield-harming global temperature rise.

Right now, we grow crops in certain densities, but our findings indicate that we will need to lower these densities to optimize growth as our climate changes. Understanding the molecualr basis of how plants respond to light and temperature will allow us to fine-tune crop density in a specific way that leads to the best yields.

Part 1

Comment by Dr. Krishna Kumari Challa on August 30, 2022 at 10:05am

Autoimmune disorders increase risk of cardiovascular disease

About 5% of the population in the world suffer from multiple autoimmune disorders. Examples are rheumatoid arthritis, psoriasis, systemic sclerosis, lupus erythematosus and type I diabetes. Although earlier research has suggested associations between some of these disorders and a higher risk of cardiovascular disease, these studies were often too small and limited to selected autoimmune or selected cardiovascular conditions to draw conclusive evidence on the necessity of cardiovascular disease prevention among patients with autoimmune disease, until now.

An international research team now presented the outcome of a thorough epidemiological investigation into possible links between 19 of the most common autoimmune disorders and cardiovascular disease. The results of the study show that patients with autoimmune disease have a substantially higher risk (between 1.4 and 3.6 times depending on which autoimmune condition) of developing cardiovascular disease than people without an autoimmune disorder. This excess risk is comparable to that of type 2 diabetes, a well-known risk factor for cardiovascular disease. The research shows for the first time that cardiovascular risks affect autoimmune disease as a group of disorders, rather than selected disorders individually.

In the research paper, which will be published in The Lancet, the authors show that the group of 19 autoimmune disorders they have studied accounts for about 6% of cardiovascular events. Importantly, excess cardiovascular risk was visible across the whole cardiovascular disease spectrum, beyond classical coronary heart disease, including infection-related heart disorders, heart inflammation, as well as thromboembolic and degenerative heart disorders, suggesting the implications of autoimmunity on cardiovascular health are likely to be much broader than originally thought.

Furthermore, the excess risk was not explained by traditional cardiovascular risk factors such as age, sex, socioeconomic status, blood pressure, BMI, smoking, cholesterol and type 2 diabetes. Another noteworthy finding: the excess risk is particularly high among patients with autoimmune disorders under 55 years and suggests that autoimmune disease is particularly important in causing premature cardiovascular disease, with the potential to result in a disproportionate loss of life years and disability.

 Autoimmune diseases and cardiovascular risk: a populationbased study on 19 autoimmune diseases and 12 cardiovascular diseases in 22 million individuals in the UK, The Lancet (2022). DOI: 10.1016/S0140-6736(22)01349-6

 

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