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Restoring a missing slice of sunshine to indoor light may help prevent myopia

Myopia, or nearsightedness, develops when the eye grows too long from front to back. This prevents images from focusing directly on the retina in the back of the eye, causing distant objects to appear blurry.

Myopia usually begins in childhood and can progress through adolescence. Beyond the need for glasses or contact lenses, high myopia increases the risk of vision-threatening complications later in life, including retinal detachment, glaucoma and macular degeneration.

Research has already shown that the more time children spend playing with screens indoors instead of outdoors, the more likely they are to develop myopia. In fact, some experts predict that nearly 5 billion people (or 50% of the world's population) will be nearsighted by 2050.
Now, a new study led by vision researchers suggests that myopia can be prevented with improved indoor lighting.

Details were published online Aug. 18, 2026, in Cell Reports Medicine.

The research focuses on indigo light—a short-wavelength light that is abundant in sunlight but poorly represented in standard white LED lighting. In experiments involving tree shrews—an animal model with a human-like visual system—the team demonstrated that exposure to indigo light completely prevented nearsightedness from developing.
The study used tree shrews because their eyes share anatomical and optical features with human eyes.

Researchers used these animals in a series of tests that exposed them to different wavelengths of light while using a biometer to measure eye shape and axial length and an autorefractor to measure refractive changes over time.

Earlier work in mice suggested that violet light near 380 nanometers could suppress myopia and revealed that opsin 5 (OPN5), a light-sensing receptor, was required for this response. But that wavelength did not work in tree shrews because, as in humans, the ocular lens blocks most light below about 400 nanometers.

Human lenses, and now we know tree shrew lenses, don't transmit a lot of light in the ultraviolet spectrum.
The findings support a broader idea that modern indoor life has changed the lighting environment in ways that affect children's eye development. Standard white LEDs typically have a peak around 450 nanometers and emit substantial longer-wavelength light that supports vision. But they provide little of the indigo light that appears to stimulate nonvisual opsins—light-sensitive pathways involved in biological processes beyond image formation.
We evolved outside in the full-spectrum light provided by our sun. When we live inside, we don't get all the wavelengths the eye needs for normal refractive development, and so we get myopia. That's the basic message of this research paper.
One way to prevent myopia would be to encourage children to spend much more time outside, where their eyes can focus across a wider range of near and distant objects while their growing bodies are bathed in full-spectrum sunlight. But reversing the course of our increasingly technical culture appears unlikely.

Another way to prevent myopia would be to improve lighting systems.

Prevention of myopia in a near-primate by supplemental indigo light suggests a hypothesis for the myopia boom, Cell Reports Medicine (2026). DOI: 10.1016/j.xcrm.2026.102999. www.cell.com/cell-reports-medi … 2666-3791(26)00416-7

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Special aspherical glasses slow down childhood myopia progression, two-year trial finds

Nearsightedness, or myopia, makes it difficult to see distant objects, while close-up objects look clear. Caused by a combination of genetic and environmental factors, such as academic pressure or excess screen time, myopia arises from distortion in the shape of the eye. If the eye is too long or the cornea is too curved, light doesn't bend properly; as a result, it focuses in front of the retina instead of on it.

Most people with myopia won't go on to develop pathologic myopia, in which nearsightedness can lead to significant vision loss. However, experts are concerned that the more severe the myopia, the higher the risk of it becoming pathologic. That makes childhood interventions that slow myopia progression potentially valuable well beyond the school years and for long-term eye health into adulthood.

Trials in China and Vietnam showed promising results, with HAL lenses slowing the progression of myopia in children. 

The number of people who need prescription glasses to correct their vision is increasing each year as nearsightedness, or myopia, becomes more common worldwide. Current projections suggest cases could reach 50% by 2050, affecting nearly 5 billion people.

Myopia typically begins in childhood, which is why students often complain that they can't see the whiteboard or a screen clearly. Now, a recent study published in JAMA Ophthalmology has tested whether special lenses could slow the progression of pediatric nearsightedness.

Researchers conducted a two-year randomized clinical trial in which children ages 6 to 12 across the U.S. with myopia were given a highly aspherical lenslet (HAL), which combines two functions in one design: a single-vision zone that corrects refractive error and a myopia-control zone made up of 11 contiguous HAL rings.

They found that, compared with children who wore standard single-vision lenses (SVL), those with HAL saw a reduction in myopia progression of more than 70% and axial elongation of more than 50%. The HAL group's eyesight worsened by only 0.25 units, compared with 0.90 units in the SVL group.

While the lenses worked well for everyone, the treatment was most powerful in the youngest children, ages 6 to 8, in whom the HAL lenses slowed prescription changes by 87%.

The results make a case for HAL spectacle lenses as a safe and effective treatment for reducing myopia progression in children. 

Jason Shen et al, Spectacle Lenses With Highly Aspherical Lenslets for Myopia Control, JAMA Ophthalmology (2026). DOI: 10.1001/jamaophthalmol.2026.3288

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