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  • Dr. Krishna Kumari Challa

    Nighttime light exposure linked to higher heart attack and stroke rates

    A new study has found that being exposed to bright light at night can significantly increase the chances of developing serious heart problems, including heart attacks, strokes and heart failure.

    Published in JAMA Network Open, the research is the largest study of its kind to explore how personal light exposure affects heart health using data from nearly 89,000 people.

    Using wrist-worn sensors, researchers from FHMRI Sleep Health tracked over 13 million hours of light exposure and followed participants for up to 9.5 years.
    The study found that people who were exposed to the brightest light at night were much more likely to develop heart problems, with a 56% higher chance of heart failure and 47% more likely to have a heart attack.

    These risks remained high even after accounting for other factors like exercise, diet, sleep habits and genetics.

    the study highlights a risk factor that many people aren't aware of, but one that's easy to address.

    This is the first large-scale study to show that simply being exposed to light at night is a strong and independent risk factor for heart disease.

    Disrupting your body's internal circadian clock by repeatedly exposing yourself to bright light at night, when it would typically be dark otherwise, will put you at a higher risk of developing dangerous heart issues, say the researchers.

    By using blackout curtains, dimming lights, and avoiding screens before bed, we can help to reduce the health risks associated with light at night.

    The study also found that women and younger people were especially vulnerable to the impact of light exposure at night.

    Women may be more sensitive to the effects of light disrupting their body clock.

    In fact, women exposed to high levels of night light had similar heart failure risks to men, which is unusual because women typically have some natural protection against heart disease.

    We need to take our body clocks seriously. Protecting our natural sleep rhythms could be a powerful way to fight heart disease, the researchers conclude.

    Light Exposure at Night and Cardiovascular Disease Incidence, JAMA Network Open (2025). DOI: 10.1001/jamanetworkopen.2025.39031

  • Dr. Krishna Kumari Challa

    A new human clinical trial has shown that a special procedure to deliver oxygen through the rectum is safe.

    The study involved 27 healthy male volunteers in Japan who were tasked with holding between 25 and 1,500 milliliters of perfluorocarbon liquid in their rectum for an hour.

    The ‘butt-breathing’ procedure passed its first safety hurdle with flying colors.
    Now researchers hope to test what happens when that liquid contains a very high concentration of oxygen.

    The hope is that one day, a procedure like this could help people who are struggling to get enough oxygen through their lungs.

    Pigs, rodents, turtles, and some fish can breathe through their butts, so why not us?

    linkinghub.elsevier.com/retrieve/pii/S2666634025003149

  • Dr. Krishna Kumari Challa

    Pathogen disables plant ‘alarm’ to break in
    Phytophthora infestans — a fungus-like mold that causes the devastating disease potato blight — infects plants by disabling their ‘alarm system’. Researchers found that P. infestans secretes enzymes called AA7 oxidases. These enzymes damage the molecules plant cells produce to alert the immune system of an infection, which lets the microbe sneak in without being detected. “It’s like burglars cutting the wires to your home alarm before breaking in,” says biochemist and study co-author Federico Sabbadin. “The microbe has learned the plant’s own language and uses it against it.”

    https://www.nature.com/articles/s41467-025-64189-1?utm_source=Live+...