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  • Dr. Krishna Kumari Challa

    Nearly 3,000 peer-reviewed medical papers have fake citations, AI-assisted audit finds
    An AI-assisted audit of 2.5 million biomedical papers identified 4,046 fake citations across 2,810 papers, with the rate of fake references increasing over 12-fold since 2023, particularly after mid-2024. Most affected papers had not received publisher action. Recommendations include mandatory reference verification, enhanced metadata, systematic tracking, and retroactive screening to maintain research integrity.
    A new Columbia University School of Nursing AI-assisted audit reveals nearly 3,000 peer-reviewed medical papers have fake citations that do not exist in scientific databases. The results highlight an alarming trend in academic publishing as the use of AI grows.
    The research letter, "Fabricated citations: an audit across 2·5 million biomedical papers," is published in The Lancet. (Research letters published in the Correspondence section include research findings and are externally peer-reviewed. Unlike Articles containing original data, research letters are shorter and the research they contain is usually preliminary, exploratory, or reporting on early findings.)

    To conduct their analysis, the research team developed an automated verification system using AI that scanned 2.5 million papers published from January 1, 2023, to February 18, 2026, in PubMed Central's Open Access.

    Among 97.1 million verified references, they identified 4,046 fake citations across 2,810 papers. The rate has grown more than 12-fold since 2023, with the sharpest increase beginning mid-2024, coinciding with the rise of AI writing tools.

    This discovery directly impacts patients as medical professionals make treatment decisions based on clinical guidelines.
    A medical professional or clinical guideline developer has no way of knowing that the evidence they are relying on does not exist. For example, one paper we reviewed had 18 out of 30 fake references. Some of those citations are already being cited by other papers and appear in systematic reviews that inform clinical care.
    Based on their findings, the authors recommend publishers verify references with each paper submission. They also recommend that indexing services add metadata to records so that users can assess the accuracy of references.

    Lastly, the research team urges major research integrity databases to establish a dedicated category for fake references to enable systematic tracking and accountability. They call on publishers to retroactively screen existing publications and issue corrections or retractions where fake references compromise a paper's conclusions. Notably, at the time of the audit, 98.4% of affected papers had not received any publisher action.

    Maxim Topaz et al, Fabricated citations: an audit across 2·5 million biomedical papers, The Lancet (2026). DOI: 10.1016/s0140-6736(26)00603-3

    Howard Bauchner et al, Fabricated references: a new threat to editorial integrity, The Lancet (2026). DOI: 10.1016/s0140-6736(26)00798-1

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  • Dr. Krishna Kumari Challa

    Omega-3 supplements may be linked to faster cognitive decline in seniors, study finds
    Omega-3 supplementation in older adults was associated with a more rapid decline in cognitive function over five years compared to non-users, independent of APOE ε4 genetic risk. Brain imaging indicated this decline was linked to reduced cerebral glucose metabolism rather than typical Alzheimer's pathology. The findings suggest potential adverse effects of omega-3 on synaptic function in aging brains.

    Zheng-Bin Liao et al, The association between omega-3 supplementation and cognitive decline in older adults, The Journal of Prevention of Alzheimer's Disease (2026). DOI: 10.1016/j.tjpad.2026.100569

  • Dr. Krishna Kumari Challa

    Almost all plant-based meat alternatives contain mycotoxins, new research finds

    New research into plant-based food and drinks has found a prevalence of mycotoxins—naturally occurring poisonous compounds produced by fungi—in hundreds of vegetarian and vegan products. A total of 212 plant-based meat alternatives (PMBAs) and plant-based beverages (PBBs) from UK shelves were tested—and all of them contained at least one of 19 mycotoxins, with multiple products containing more than one.
    The study tested a broad spectrum of products readily available to UK consumers, such as burgers, vegetarian chicken pieces, vegan sausages, oat-, almond- and soy-based milks.

    The study, "Mycotoxin contamination in plant-based beverages and meat alternatives: A survey of the UK market," is published in Food Control.

    Mycotoxins are particularly prevalent in plant-based foods because the raw materials those foods are made from—such as grains, legumes and seeds—can be exposed to mold during cultivation and storage.

    The research team found that mycotoxin levels in the UK foods that they tested were lower than the recommended EU guideline levels, reflecting the high quality standards of the UK food industry.

    However, previous research studies have shown that even low levels, if consumed often, can build up exposure and lead to potential health concerns. So, while consuming these products in isolation is unlikely to pose issues, a diet solely based on plant-based foods could lead to a cumulative build-up of mycotoxins, potentially resulting in health problems if not managed properly.

    Raquel Torrijos et al, Mycotoxin contamination in plant-based beverages and meat alternatives: A survey of the UK market, Food Control (2026). DOI: 10.1016/j.foodcont.2025.111910