Engineered soil bacterial protein kills colorectal cancer cells by targeting their mitochondria
An engineered protein derived from soil bacteria, combined with a fatty acid to form the NheA-O complex, selectively induces ferroptosis in colorectal cancer cells by targeting and disrupting mitochondrial energy production. This approach bypasses typical tumor cell survival mechanisms, leading to efficient cancer cell death in cell culture models and suggesting a potential new therapeutic strategy.

Naeem Ullah et al, Bacterial protein-oleate complexes induce ferroptosis-like cell death in colorectal cancer cells by disrupting cell membranes and inhibiting the β-catenin-GPX4 axis, Cell Death Discovery (2026). DOI: 10.1038/s41420-026-03097-9

How does imagination really work in the brain? New explanation upends what we knew
Imagination operates by modulating and suppressing ongoing spontaneous neural activity in the brain, rather than generating new activity. Visual imagery emerges when feedback signals selectively dampen competing neural patterns, allowing specific mental images to stabilize amid background activity. This mechanism explains why imagined images are typically weaker and more distinct from real perception.

https://psycnet.apa.org/fulltext/2027-53139-001.html

HEPA air purifiers may boost brain power in adults over 40
One month of in-home HEPA air purifier use led to a 12% improvement in mental flexibility and executive function among adults aged 40 and older, compared to a sham purifier. The cognitive benefit was similar to that seen with increased exercise. The findings suggest HEPA purifiers may help mitigate cognitive impacts of air pollution, particularly for those living near major roadways.

https://www.nature.com/articles/s41598-026-48063-8