Ex-Harvard Medical School faculty member warns COVID-19 herd immunity is ‘wishful thinking'
A Washington D.C.-based internist and former Harvard Medical School faculty member has claimed the idea that herd immunity may slow the coronavirus pandemic is "wishful thinking" after a 50-year-old patient was infected for a second time with COVID-19.
"During his first infection, my patient experienced a mild cough and sore throat," Dr. Clay Ackerly explained in an opinion piece for Vox. "His second infection, in contrast, was marked by a high fever, shortness of breath, and hypoxia, resulting in multiple trips to the hospital.
"It is possible, but unlikely, that my patient had a single infection that lasted three months," Dr. Ackerly added. "Some Covid-19 patients (now dubbed 'long haulers') do appear to suffer persistent infections and symptoms.
"My patient, however, cleared his infection — he had two negative PCR tests after his first infection — and felt healthy for nearly six weeks."
Typically, experts estimate that between 70 and 90 percent of a population must be immune to a contagious disease to achieve herd immunity -- whether through vaccination or other exposure to an infection.
However, a recent study in Spain, one of the countries hardest-hit by the pandemic, found just five percent of those surveyed had coronavirus antibodies. On a regional basis, the percentage varied from fewer than three percent in coastal regions to more than 10 percent in areas around Madrid.
An exploding white dwarf star blasted itself out of its orbit with another star in a "partial supernova" and is now hurtling across our galaxy, according to a new study from the University of Warwick.
Scientists uncover key process in the manufacture of ribosomes and proteins
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Scientists discover heavy element chemistry can change at high pressures
New research shows that one of the heaviest known elements can be manipulated to a greater degree than previously thought, potentially paving the way for new strategies to recycle nuclear fuel and better long-term storage of radioactive elements.
Bacteria with a metal diet discovered in dirty glassware
Microbiologists have discovered bacteria that feed on manganese and use the metal as their source of calories. Such microbes were predicted to exist over a century ago, but none had been found or described until now.
The study also reveals that the bacteria can use manganese to convert carbon dioxide into biomass, a process called chemosynthesis. Previously, researchers knew of bacteria and fungi that could oxidize manganese, or strip it of electrons.
Researchers found the bacteria serendipitously after performing unrelated experiments using a light, chalk-like form of manganese. They had left a glass jar soiled with the substance to soak in tap water in their office sink before departing for several months to work off campus. When they returned, the jar was coated with a dark material.
They wondered, 'What is that?' and systematically performed tests to figure that out.
The black coating was in fact oxidized manganese generated by newfound bacteria that had likely come from the tap water itself. There is evidence that relatives of these creatures reside in groundwater.
Manganese is one of the most abundant elements on the surface of the earth. Manganese oxides take the form of a dark, clumpy substance and are common in nature; they have been found in subsurface deposits and can also form in water-distribution systems.
There is a whole set of environmental engineering literature on drinking-water-distribution systems getting clogged by manganese oxides. But how and for what reason such material is generated there has remained an enigma. Clearly, many scientists have considered that bacteria using manganese for energy might be responsible, but evidence supporting this idea was not available until now.
The finding helps researchers better understand the geochemistry of groundwater. It is known that bacteria can degrade pollutants in groundwater, a process called bioremediation. When doing this, several key organisms will "reduce" manganese oxide, which means they donate electrons to it, in a manner similar to how humans use oxygen in the air. Scientists have wondered where the manganese oxide comes from in the first place.
The bacteriadiscovered now can produce it, thus they enjoy a lifestyle that also serves to supply the other microbes with what they need to perform reactions that we consider to be beneficial and desirable.
The research findings also have possible relevance to understanding manganese nodules that dot much of the seafloor.
In analyzing blood, tissue, immune cellsand other samples from the patients, the researchers came upon what they think is a signature for people with severe infections—a combination of aninterferonresponsedeficiency and exacerbated inflammation. They suggest the signature may represent a hallmark for severely ill COVID-19 patients. The researchers suggest their findings could lead to therapies that boost interferon response to aninfectionwhile also reducing inflammation.
More specifically, the researchers found that critically ill patients had a deficiency in the response of type I interferons—a kind of protein that is used by the immune systemto fight infections. In addition, there were higher than normal levels of proinflammatory signaling. Together, the two responses left patients with little ammunition to fight their infections. The work builds on studies by other researchers finding that interferon signaling in infected areas may play a role in mitigating disease progression. Such work has shown that duration, timing and location of interferon exposure to the virus are critical factors that appear to underlie the degree of success with current therapies.
Jérôme Hadjadj et al, Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients, Science (2020). DOI: 10.1126/science.abc6027
Invasive alien species may soon cause dramatic global biodiversity loss
An increase of 20 to 30 per cent of invasive non-native (alien) species would lead to dramatic future biodiversity loss worldwide. This is the conclusion of a study by an international team of researchers.
Human activities intentionally and unintentionally introduce more and more plant and animal speciesto new regions of the world—for example, via commodity transport or tourism.
Some of these alien specieshave negative consequencesfor biodiversity and humans well-being, for example by displacing native species or transmitting diseases. However, while we have relatively good information on the historical spread of alien species, there is still little knowledge about their future development.
The study shows that an increase of 20 to 30 per cent in the number of newly introduced alien species is considered sufficient to cause massive global biodiversity loss—a value that is likely to be reached soon, as the number of introduced species is constantly increasing.
humans are the main driver of the future spread of alien species. The experts identify three main reasons, primarily the increasing global transport of goods, followed by climate change and then the impacts of economic development such as energy consumption and land use. The study also shows that the spread of alien species can be greatly slowed down by ambitious countermeasures.
Franz Essl et al, Drivers of future alien species impacts: An expert‐based assessment, Global Change Biology (2020). DOI: 10.1111/gcb.15199
On Antarctica, humanity's small footprint has big impact
Humanity's accelerating impact on the vast wilderness of Antarctica extends well beyond scientific stations and eco-tourism along its fringes, both in scope and intensity, scientists warned
Using fiber-catching devices as part of the laundry process can dramatically reduce the amount of microscopic particles potentially entering the marine environment, according to new research.
Devices can reduce fibers produced in laundry cycle by up to 80%
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Blood vessels communicate with sensory neurons to decide their fate
Blood vessels communicate with sensory neurons to decide whether they remain as a reservoir of stem cells or differentiate
Siberia heat 'almost impossible' without climate change
A heatwave in Siberia that saw temperature records tumble as the region sweltered in 38-degree Celsius highs was "almost impossible" without the influence of manmade climate change, leading scientists said.
An international team of researchers found that the record-breaking warm period was more than 2C hotter than it would have been if humans had not warmed the planet through decades of greenhouse gas emissions.
This is further evidence of the extreme temperatures we can expect to see more frequently around the world in a warming climate.
Immunity toCOVID-19may not last. This threatens a vaccine and herd immunity
Animportant new studyreleased online this week could have a large bearing on how our future looks in 2021 and beyond.
It suggests our immunity to SARS-CoV-2 does not last very long at all — as little as two months for some people. If this is the case, it means a potential vaccine might require regular boosters, and herd immunity might not be viable at all.
An international team of scientists has found that instead of lithium (Li), sodium (Na) "stacked" in a special way can be used for battery production. Sodium batteries would be significantly cheaper and equivalently or even more capacious than existing lithium batteries.
Scientists achieve major breakthrough in preserving integrity of sound waves
In a breakthrough for physics and engineering, researchers have presented the first demonstration of topological order based on time modulations. This advancement allows the researchers to propagate sound waves along the boundaries of topological metamaterials without the risk of waves traveling backwards or being thwarted by material defects.
Sperm discovery reveals clue to genetic 'immortality'
New insights into an elusive process that protects developing sperm cells from damage in growing embryos, sheds light on how genetic information passes down, uninterrupted, through generations.
The study identified a protein, known as SPOCD1, which plays a key role in protecting the early-stage precursors to sperm, known asgerm cells, from damage in a developing embryo.
During their development, germ cells undergo a reprogramming process that leaves them vulnerable to rogue genes, known as jumping genes, which can damage their DNA and lead to infertility.
Reprogramming is essential for correct germ cell development in embryos, but leaves them temporarily vulnerable to a subset their own genes, known as jumping genes, that threaten genetic chaos.
Evading such damage allows germ cells to become the pool of self-renewing cells that produce healthy sperm throughout adult life.
Germ cells are the vital link between generations but they need unique strategies to protect the genetic information they carry, so it can be passed successfully from parents to their offspring.
The study is the first to reveal the role of the SPOCD1 protein, which helps to recruit protective chemical tags, known as DNA methylations, to disable jumping genes.
Scientists have long puzzled over howgermcellsescape damage during thereprogramming process, as it temporarily wipes their genetic slate clean of existing protective tags.
"The identification of SPOCD1 finally opens the doors to further investigation that will give a more elaborate understanding of this elusive process and male fertility.
Tests in male mice revealed that loss of this protein leads to infertility because the DNA methylation process does not happen correctly, allowing jumping genes to damage the developing sperms' DNA.
Jumping genes make up over half of our DNA and move around the genome controlling how our genes are used. But their activity needs to be carefully regulated to avoid them causing damage.
The team discovered that early sperm's secret line of defence is activated when SPOCD1 binds with another protein, known as MIWI2, which is already known to have a role in silencing jumping genes.
Previous studies revealed that MIWI2 protein is bound to small molecules, known as piRNAs, that play a key role in disabling jumping genesthrough DNA methylation.
Ansgar Zoch et al. SPOCD1 is an essential executor of piRNA-directed de novo DNA methylation, Nature (2020). DOI: 10.1038/s41586-020-2557-5
Tiny, needle-like fibers that can become airborne if bedrock is disturbed during earthworks has the potential to cause asbestos-type disease and should be investigated, scientists say.
A new facility will store tens of thousands of cryogenically-frozen people. The hope is to one day bring them back to life, but just how realistic are its aims?
Study reveals strange magnetic behaviour 8-11 million years ago
Research has revealed that strange behaviour of the magnetic field in the South Atlantic region existed as far back as eight to 11 million years ago, suggesting that today's South Atlantic Anomaly is a recurring feature and unlikely to represent an impending reversal of the Earth's magnetic field.
The South Atlantic Anomaly is an area characterized by a significant reduction in the strength of Earth's magnetic field compared with areas at similar geographic latitudes. Here, protection from harmful radiation from space is reduced. The most significant signs of this are technical malfunctions aboard satellites and spacecraft.
The geomagnetic records from the rocks covering 34 different volcanic eruptions that took place between eight and 11 million years ago revealed that at these occurrences the direction of the magnetic field for St Helena often pointed far from the North pole, just like it does today.
The Earth's magnetic field, or the geomagnetic field, not only gives us the ability of navigating with a compass, but also protects our atmosphere from charged particles coming from the sun, called solar wind. However, it is not completely stable in strength and direction, both over time and space, and it has the ability to completely flip or reverse itself with substantial implications.
The South Atlantic Anomaly is a topic of debate between scientists in this field. Besides the fact that it causes damages to space technology, it also raises the question of where it comes from and whether it represents the start of the total weakening of the field and a possible upcoming pole reversal.
study provides the first long term analysis of the magnetic field in this region dating back millions of years. It reveals that theanomalyin the magnetic field in the South Atlantic is not a one-off, similar anomalies existed eight to 11 million years ago.
"This is the first time that the irregular behaviour of the geomagnetic field in the South Atlantic region has been shown on such a long timescale. It suggests that the South Atlantic Anomaly is a recurring feature and probably not a sign of an impending reversal.
"It also supports earlier studies that hint towards a link between the South Atlantic Anomaly and anomalous seismic features in the lowermost mantle and the outer core. This brings us closer to linking behaviour of the geomagnetic field directly to features of the Earth's interior"
Elevated paleomagnetic dispersion at Saint Helena suggests long-lived anomalous behavior in the South Atlantic, Proceedings of the National Academy of Sciences (2020). DOI: 10.1073/pnas.2001217117
Using drones to reduce disease-spreading mosquito populations
Vector-borne diseases are illnesses that can be transmitted to humans by blood-feeding insects, such as mosquitoes, ticks and fleas. Mosquitoes are known to contribute to the spread of a number of vector-borne diseases, including malaria, dengue, yellow fever and Zika.
According to the World Health Organization (WHO), this class of diseases accounts for 17% of all infectious diseases in the world, causing over 1 million human deaths per year. Developing methods to reduce the spread and prevalence of these diseases is thus of utmost importance, as it could ultimately save countless human lives.
In recent years, scientists have devised a number of control methods to reduce or manage harmful insect populations without injecting harmful chemicals into the environment. One of these methods is the sterile insect technique(SIT), a form of insect birth control that entails the use of radiation to sterilize male mosquitoes, which are then released into the air in a target area and start mating with wild female insects.
As a sterile male and a fertile female do not produce any offspring after they mate, SIT produces a decline in the insect population. In order to reduce the incidence of vector-borne diseases, however, large amounts of good quality sterile insects need to be released continuously over affected geographical areas. Techniques for the cost-effective aerial release of sterile mosquitoes over extended geographical regions are thus a bottleneck to enabling the application of SIT on a large scale.
Researchers have recently developed a system to apply the SIT using unmanned aerial vehicles (UAVs), or drones, to manage and reduce vector-borne-disease-transmitting mosquito populations. This unique system entails the release of sterile mosquitoes in the air over large geographical areas using UAVs or drones. The system, tested in Brazil, enabled a uniform dispersal of sterile male Aedes aegypti mosquitoes while maintaining their quality, leading to a consistent sterile-to-wild male ratio.
The key goal of the study was to measure the survival, dispersal and sexual competitiveness of sterile male mosquitoes after they were mass-produced, sorted, handled, irradiated, marked and released within a geographical area using UAVs. The UAV-based release system they devised uses a canister in which mosquitoes are chilled down to 8-12 °C and compacted. Each canister can contain up to 50,000 sterile males. When the canister opens, the mosquitoes fall into a rotating cylinder that releases them into the open air with each of its rotations. The rotation speed controls the number of sterile males released per minute. It is fully automated, and release rates can be controlled depending on the location and speed of the drone.
J. Bouyer et al. Field performance of sterile male mosquitoes released from an uncrewed aerial vehicle, Science Robotics (2020). DOI: 10.1126/scirobotics.aba6251
Oh No, Salmonella Has Found a Way to Avoid Being Washed Off Our Salads
Some Salmonella bacteria strains have found a way of evading plant defences and sneaking their way into leafy greens – a strategy that's effective enough to protect them against plant immune systems and from being washed off in the kitchen.
Could COVID-19 Trigger Chronic Disease in Some People?
A handful of viruses have been associated with long-term, debilitating symptoms in a subset of those who become infected. Early signs hint that SARS-CoV-2 may do the same.
Inventory of the human gut ecosystem: An international team of scientists has collated all known bacterial genomes from the human gut microbiome into a single large database, allowing researchers to explore the links between bacterial genes and proteins, and their effects on human health.
Chronic inflammation alters the evolution of cells in the colon, study finds: researchers have compared diseased colon with healthy tissue to better understand how inflammatory bowel disease (IBD) is linked to an increased risk of colorectal cancers, at a molecular level.
New model proposed to reduce carbon footprint: to bring the carbon footprint of international conferences down. The model can apply to small regional conferences as well. The model identifies three key areas for action; carefully selecting venues to minimize transport emissions, hosting conferences every second year to instantly cut travel by 50%, and creating hubs so people travel shorter distances to still benefit from networking while linking virtually to other hubs.
Genomic basis of bat superpowers revealed: Like how they survive deadly viruses
The genetic material that codes for bat adaptations and superpowers—such as the ability to fly, to use sound to move effortlessly in complete darkness, to tolerate and survive potentially deadly viruses, and to resist aging and cancer—has been revealed and published.
One aspect of the paper findings shows evolution through gene expansion and loss in a family of genes, APOBEC3, which is known to play an important role in immunity to viruses in other mammals. The details in the paper that explain this evolution set the groundwork for investigating how these genetic changes, found in bats but not in other mammals, could help prevent the worst outcomes of viral diseases in other mammals, including humans.
The team compared these bat genomes against 42 other mammals to address the unresolved question of where bats are located within the mammalian tree of life. Using novel phylogenetic methods and comprehensive molecular data sets, the team found the strongest support for bats being most closely related to a group called Fereuungulata that consists of carnivorans (which includes dogs, cats and seals, among other species), pangolins, whales and ungulates (hooved mammals).
To uncover genomic changes that contribute to the unique adaptations found in bats, the team systematically searched for gene differences between bats and other mammals, identifying regions of the genomethat have evolved differently in bats and the loss and gain of genes that may drive bats' unique traits
The researchers found evidence the exquisite genomes revealed "fossilized viruses," evidence of surviving past viral infections, and showed that bat genomes contained a higher diversity of these viral remnants than other species providing a genomic record of ancient historical interaction with viral infections. The genomes also revealed the signatures of many other genetic elements besides ancient viral insertions, including 'jumping genes' or transposable elements.
A team of researchers has succeeded in diffracting a beam of organic molecules. In their paper published in the journal Physical Review Letters, the researchers describe demonstrating Bragg diffraction of the molecules ciprofloxacin and phthalocyanine.
Over the long history of wave-particle research, scientists have found that light is both a wave and a particle. They have also shown that electrons have a similar wave-particle duality. Physicists theorize that wave-particle duality is a fundamental feature of the universe. This suggests that all matter should have wave-like phenomena, which means that it should be able to behave in ways that are similar to light and electrons. As one example, it should be possible to demonstrate interference and diffraction of matter, such as whole molecules. In this new effort, the researchers have done exactly that by demonstrating a type of diffraction pattern with molecules of ciprofloxacin (an antibiotic) and phthalocyanine (a kind of dye).
The work involved firing a laser beam at a sheet of glass upon which the ciprofloxacin and phthalocyanine molecules were applied, forcing them to fly off the glass at a very rapid speed. The molecules flew toward a barrier with a vertical slit that allowed only those molecules traveling in the desired direction to pass through. Those that passed through were met by another laser beam focused with a standing wave pattern. The high-intensity parts of the beam deflected the molecules in a way akin to passing through a gap, which led to the creation of a diffraction pattern. The molecules were then directed through another slit and immediately thereafter impacted a flat screen, where they adhered. And because the types of molecules the researchers chose for the experiment glow when exposed to UV or blue light, the researchers were able to see them. By running the experiment for a short period of time, the researchers were able to observe a pattern appear on the screen—evidence of a diffraction pattern.
The researchers were able to create different patterns by using different initial laser velocities and different incident angles. They note also that the patterns were weak, though still observable, and agreed with theory.
Evidence of "hormone disruptor" chemical threats grows
A growing number of chemicals in pesticides, flame retardants, and certain plastics have been linked to widespread health problems including infertility, diabetes, and impaired brain development, a set of reviews of hundreds of studies concludes.
Quantum Tunneling Is Not Instantaneous, Physicists Show
A new experiment tracks the transit time of particles burrowing through barriers, revealing previously unknown details of a deeply counterintuitive phenomenon
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** New research identifies the rules that termites use to build their nests
The popular view of biometric security often invokes fingerprint readers, iris or retinal scans, and voice-activated systems. However, any unique human characteristic whether the shape of one's ears, the whole face, the pattern of blood vessels in the back of the hand, walking pattern, heart rhythm or even how one types at a keyboard, might be used to provide a secure signature of login. Some traits are easier to analyze than others and some, such as fingerprints, can be spoofed.
Research published in the International Journal of Biometrics has taken an amusing trait to demonstrate how the way a person laughs might be used in biometrics.
people can recognize other people by the unique nature of their laughter, perhaps in an even more obvious way than their voice. Moreover, while many people are adept at impersonating the voices of other people, mimicking someone's laugh is far more difficult. The team has now used statistical analyses of the various audible frequencies present in a person's laugh to create adigital signaturefor each uniquelaugh.
Tests on the approach show their prototype recognition algorithm to be 90 percent accurate, which compares very favorably with the 65% accuracy of a conventional Gaussian model. However, combining their algorithm with the Gaussian approach can boost accuracy overall by more than 5 percent.
Comfort Oluwaseyi Folorunso et al. Laughter signature: a novel biometric trait for person identification, International Journal of Biometrics (2020). DOI: 10.1504/IJBM.2020.108480
estimate that more than 100 million lighting strikes on land each year will radically alter forests and other ecosystems in the region between the Tropic of Cancer and the Tropic of Capricorn.
How mosquitoes got their taste for human blood and what it means for the future
Of about 3,500 mosquito species around the world, only a few have taken to specifically targeting people for biting, making them important spreaders of infectious diseases. To predict and help control the spread of those mosquito-borne illnesses, it's important to know where and why, evolutionarily speaking, certain mosquitoes got their taste for biting humans in the first place. Now, researchers reporting in the journal Current Biology on July 23 have identified two major factors: a dry climate and city life. Based on these findings, they predict that increased urbanization in the coming decades will mean even more human-biting mosquitoes in the future. They
found that in their native range of sub-Saharan Africa, they show extremely variable attraction to human hosts, ranging from strong preference for humans to strong preference for non-human animals."
"Mosquitoes living near dense human populations in cities such as Kumasi, Ghana, or Ouagadougou, Burkina Faso, showed increased willingness to bite human hosts," adds Noah Rose, also of Princeton. "But they only evolve a strong preference for human hosts in places with intense dry seasons—in particular, in the Sahel region, where rainfall is concentrated in just a couple months out of the year. We think this is because mosquitoes in these climates are especially dependent on humans and human water storage for their life cycle."
Noah H. Rose et al, Climate and Urbanization Drive Mosquito Preference for Humans, Current Biology (2020). DOI: 10.1016/j.cub.2020.06.092
Worryingly, research from space flight missions has shown bacteria become more deadly and resilient when exposed to microgravity (when only tiny gravitational forces are present).
Adding to that, bacteria also seem tomutate quickerin space. However, these mutations are predominately for the bacteria toadapt to the new environment– not to become super deadly.
More research is needed to examine whether such adaptations do, in fact, allow the bacteria to cause more disease.
L-type calcium channel blockers may contribute to heart failure, study finds
L-type calcium channel blockers (LCCBs)—the most widely used drugs for treating hypertension—may harm the heart as much as help it, according to a new study.
Coronavirus makes changes that cause cells not to recognize it
With an alarm code, we can enter a building without bells going off. It turns out that the SARS coronavirus 2 (SARS-CoV-2) has the same advantage entering cells. It possesses the code to waltz right in.
How can the coronavirus achieves this?
The scientists resolved the structure of an enzyme called nsp16, which the virus produces and then uses to modify its messenger RNA cap. It's a camouflage. Because of the modifications, which fool the cell, the resulting viral messenger RNA is now considered as part of the cell's own code and not foreign.
How do scientists overcome this?
Deciphering the 3-D structure of nsp16 paves the way for rational design of antiviral drugs for COVID-19 and other emerging coronavirus infections. The drugs, new small molecules, would inhibit nsp16 from making the modifications. The immune system would then pounce on the invading virus, recognizing it as foreign.
Neanderthal gene linked to increased pain sensitivity
People who have inherited nerve-altering mutations from the ancient hominins tend to experience more pain.
Despite their rough and tumble existence, Neanderthals had a biological predisposition to a heightened sense of pain, finds a first-of-its kind genome study published in Current Biology on 23 July . Evolutionary geneticists found that the ancient human relatives carried three mutations in a gene encoding the protein NaV1.7, which conveys painful sensations to the spinal cord and brain. They also showed that in a sample of British people, those who had inherited the Neanderthal version of NaV1.7 tend to experience more pain than others.
Mutations in a gene called SCN9A — which encodes the NaV1.7 protein — stood out because all of the Neanderthals had three mutations that alter the shape of the protein. The mutated version of the gene was found on both sets of chromosomes in all three Neanderthals, hinting that it was common across their populations.NaV1.7 acts in the body’s nerves, where it is involved in controlling whether and to what extent painful signals are transmitted to the spinal cord and brain. “People have described it as a volume knob, setting the gain of the pain in nerve fibres,” says Zeberg. Some people with extremely rare genetic mutations that disable the protein do not feel pain, whereas other changes can predispose people to chronic pain.
Quantum Tunneling Is Not Instantaneous, Physicists Show
A new experiment tracks the transit time of particles burrowing through barriers, revealing previously unknown details of a deeply counterintuitive phenomenon
In cell studies, seaweed extract outperforms remdesivir in blocking COVID-19 virus
Heparin, a common anitcoagulent, could also form basis of a viral trap for SARS-CoV-2
In a test of antiviral effectiveness against the virus that causes COVID-19, an extract from edible seaweeds substantially outperformed remdesivir, the current standard antiviral used to combat the disease.
To get an idea of how much this might happen, a simple test involving trying to blow out a candle directly in front of the wearer could be tried. Initially, the distance coupled with the strength of exhalation could be investigated, but then face coverings made from different materials and critically with different numbers of layers could be tried. The design of face covering that made it hardest to divert the candle flame will probably provide the best barrier for projecting the virus forward and through the face covering.
Meta-Research: The growth of acronyms in the scientific literature
Abstract
Some acronyms are useful and are widely understood, but many of the acronyms used in scientific papers hinder understanding and contribute to the increasing fragmentation of science. Here we report the results of an analysis of more than 24 million article titles and 18 million article abstracts published between 1950 and 2019. There was at least one acronym in 19% of the titles and 73% of the abstracts. Acronym use has also increased over time, but the re-use of acronyms has declined. We found that from more than one million unique acronyms in our data, just over 2,000 (0.2%) were used regularly, and most acronyms (79%) appeared fewer than 10 times. Acronyms are not the biggest current problem in science communication, but reducing their use is a simple change that would help readers and potentially increase the value of science.
Psychologists show that embedding primes in a person's speech can influence people's decision making
psychologists found that embedding primes in a person's speech and gestures can influence people's decision-making
In both psychology and magic circles, primes are known as actions or words that unconsciously influence the thinking of another person One example is a policeman interrogating a witness tapping his ring while inquiring about jewelry a suspect might have been wearing. It is a technique magicians have used for years. They prime a person or audience by giving them subtle verbal or physical clues to get them to choose anumberduring a guessing trick, or a card during a card trick. In this new effort, the researchers tested the practice to see if it actually works.
The experiments involved asking volunteers to watch a live or taped performance of a person who, unbeknownst to them, was trying to prime them. The research began with 90 volunteers who were split into two groups. One group watched Pailhès (who is also an amateur magician) perform a live magic act—the other group watched a video version of the same act on a laptop. The act consisted of attempting to get thecrowdof observers to pick a predesignated card—the three ofdiamonds.
As part of the routine, she mimicked an act by British illusionist Derren Brown in which he asks a member of the crowd to mentally transmit the correct card to the others in the crowd. He also asks the crowd to think about a bright, vivid colored card (more descriptive of a red card than a black one). He also mimes the shape of a diamond with his hands and asks the audience to think of the little numbers at the corners (ruling out double digits and face cards) and even draws the number "3" in the air with his hands—and asks the audience to imagine things in the middle as he says, "boom, boom, boom."
After mimicking this act, the researchers asked the audience members to write down a card by suit and number, which they turned in. Inspection of the cards showed that 17.8 percent of theaudiencemembers chose the three of diamonds—38.9 percent chose a three of any suit and 33.3 percent chose a diamond of any number, results that were far better than chance.
Alice Pailhès et al. Influencing choices with conversational primes: How a magic trick unconsciously influences card choices, Proceedings of the National Academy of Sciences (2020). DOI: 10.1073/pnas.2000682117
Researchers create 'decoy' coatings that trick infrared cameras
Light can sometimes play tricks on our eyes. If you look at a shiny surface, what you see will largely depend on the surrounding environment and lighting conditions.
Researchers have now taken ocular distortion a step further, finding a way to imbed visual "decoys" into surfaces of objects in a way that can fool people into thinking they detect a specific image in the infrared that actually isn't there.
Infrared light is invisible to the human eye, but can be detected by a range of devices, such as night-vision goggles and thermal-imaging cameras. In this work,researchers can effectively tune target objects into emitting the same infrared radiation as the surrounding environment, making them invisible to infrared detection devices.
But what makes the researchers' work particularly novel is that they can manipulate the coatings in a way that a person trying to view the object with such a device would instead see a false image.
"This structure offers a general platform for unprecedented manipulation and processing of infrared signals.
this method provides better, more consistent camouflage because the product is mechanically flexible, power free and inherently self-adaptive to temporal fluctuation as well as spatial variation of the targettemperature.
Additionally, by manipulating the configuration and composition of tungsten-dopedvanadium dioxideon coatings applied to the PE tape, researchers can create an infrared decoy.
"How we grow the material changes the image people ultimately think they see.
This kind of technology could prove useful for military and intelligence agencies, as they seek to thwart increasingly sophisticated surveillance technologies that pose a threat to national security. It might also incubate future encryption technology, allowing information to be safely concealed from unauthorized access.
Kechao Tang et al. A Thermal Radiation Modulation Platform by Emissivity Engineering with Graded Metal–Insulator Transition, Advanced Materials (2020). DOI: 10.1002/adma.201907071
Testing Chernobyl fungi as a radiation shield for astronauts
How can astronauts survive high radiations during interplanetary travel?
A team of researchers has tested the viability of using a type of fungus found growing in some of the destroyed nuclear reactors at the former Chernobyl nuclear power plant site to shield astronauts from radiation.
Some fungi are able to flourish in a very highly radioactive place here on Earth—inside the destroyed reactors at the Chernobyl site in Ukraine. Testing of several types of the fungi has showed that they not only survive in the former reactors, but actually flourish. They have the ability to absorb radiation and to convert it into energy for their own use. To look into the possibility of using such types of fungus as a shield for humans, the researchers arranged with NASA to send a sample of one of the types of fungus found at Chernobyl—cladosporium sphaerospermum—to the International Space Station.
Once the fungus sample arrived at the ISS, astronauts monitored the petri dish set up by the researchers. One side of the petri dish was coated with the fungus; the other side had no fungus and served as a control. A detector was affixed to the back of the petri dish to measure radiation coming through. The detector was monitored for 30 days. The researchers found that the side of the petri dish that was covered with fungus reduced radiation levels coming through the dish by approximately 2% compared to the control side. That alone is inadequate as a safety shield, but the experiment serves as an indicator of what might be possible. On its own, the fungus is known to grow, which means a rocket carrying humans could carry just a small amount with them. Once on Mars, the fungus could be cultivated on a shield structure and allowed to thicken, offering perhaps one layer of protection very nearly free of charge.
Graham K. Shunk et al. A Self-Replicating Radiation-Shield for Human Deep-Space Exploration: Radiotrophic Fungi can Attenuate Ionizing Radiation aboard the International Space Station, bioRxiv (2020). DOI: 10.1101/2020.07.16.205534
A scientist's mesmerizing animation shows how our entire solar system orbits an unseen center — and it's not the sun
A scientist's mesmerizing animation shows how our entire solar system orbits an unseen center — and it's not the sun: That center of mass is called the barycenter
New study reveals how day- and night-biting mosquitoes respond differently to colours of light and time of day
Researchers found that night- versus day-biting species of mosquitoes are behaviorally attracted and repelled by different colors of light at different times of day. Mosquitoes are among major disease vectors impacting humans and animals around the world and the findings have important implications for using light to control them.
The team studied mosquito species that bite in the daytime (Aedes aegypti, aka the Yellow Fever mosquito) and those that bite at night (Anopheles coluzzi, a member of the Anopheles gambiae family, the major vector for malaria). They found distinct responses to ultra violet and other colors of light between the two species. Researchers also found light preference is dependent on the mosquito's sex and species, the time of day and the colour of the light.
Insects are non-specifically attracted to ultraviolet light, hence the widespread use of ultraviolet light "bug zappers" for insect control. this research found that day-biting mosquitoes are attracted to a wide range of light spectra during the daytime, whereas night-biting mosquitoes are strongly photophobic to short-wavelength light during the daytime. Therefore, timing and light spectra are critical for species-specific light control of harmful mosquitoes.
The new work shows that day-biting mosquitoes, particularly females that require blood meals for their fertilized eggs, are attracted to light during the day regardless of spectra. In contrast, night-biting mosquitoes specifically avoid ultraviolet (UV) and blue light during the day. Previous work using fruit flies(which are related to mosquitoes) has determined the light sensors and circadian molecular mechanisms for light mediated attraction/avoidance behaviours. Accordingly, molecular disruption of the circadian clock severely interferes with light-evoked attraction and avoidance behaviours in mosquitoes. At present, light-based insect controls do not take into consideration the day versus night behavioural profiles that change with daily light and dark cycles.
Light is the primary regulator of circadian rhythms and evokes a wide range of time-of-day specific behaviours. By gaining an understanding of how insects respond to short wavelength lightin a species-specific manner, we can develop new, environmentally friendly alternatives to controlling harmful insects more effectively and reduce the need for environmentally damaging toxic pesticides.
Lisa S. Baik et al, Circadian Regulation of Light-Evoked Attraction and Avoidance Behaviors in Daytime- versus Nighttime-Biting Mosquitoes, Current Biology (2020). DOI: 10.1016/j.cub.2020.06.010
Discovery will allow more sophisticated work at nanoscale
The movement of fluids through small capillaries and channels is crucial for processes ranging from blood flow through the brain to power generation and electronic cooling systems, but that movement often stops when the channel is smaller than 10 nanometers.
Researchers have reported a new understanding of the process and why some fluids stagnate in these tiny channels, as well as a new way to stimulate the fluid flow by using a small increase in temperature or voltage to promote mass and ion transport.
The work explores the movement of fluids with lower surface tension, which allows the bonds between molecules to break apart when forced into narrow channels, stopping the process of fluid transport, known as capillary wicking.
This capillary force drives liquid flow in small channels and is the critical mechanism for mass transport in nature and technology—that is, in situations ranging from blood flow in the human brain to the movement of water and nutrients from soil to plant roots and leaves, as well as in industrial processes.
But differences in the surface tension of some fluids causes the wicking process—and therefore, the movement of the fluid—to stop when those channels are smaller than 10 nanometers. The researchers reported that it is possible to prompt continued flow by manipulating the surface tension through small stimuli, such as raising the temperature or using a small amount of voltage.
The temperature even slightly can activate movement by changing surface tension, which they dubbed "nanogates." Depending on the liquid, raising the temperature between 2 degrees Centigrade and 3 degrees C is enough to mobilize the fluid.The surface tension can be changed through different variables.
The simplest one is temperature. If you change temperature of the fluid, you can activate this fluid flow again." The process can be fine-tuned to move the fluid, or just specific ions within it, offering promise for more sophisticated work at nanoscale.
Dr. Krishna Kumari Challa
Ex-Harvard Medical School faculty member warns COVID-19 herd immunity is ‘wishful thinking'
A Washington D.C.-based internist and former Harvard Medical School faculty member has claimed the idea that herd immunity may slow the coronavirus pandemic is "wishful thinking" after a 50-year-old patient was infected for a second time with COVID-19.
"During his first infection, my patient experienced a mild cough and sore throat," Dr. Clay Ackerly explained in an opinion piece for Vox. "His second infection, in contrast, was marked by a high fever, shortness of breath, and hypoxia, resulting in multiple trips to the hospital.
"It is possible, but unlikely, that my patient had a single infection that lasted three months," Dr. Ackerly added. "Some Covid-19 patients (now dubbed 'long haulers') do appear to suffer persistent infections and symptoms.
"My patient, however, cleared his infection — he had two negative PCR tests after his first infection — and felt healthy for nearly six weeks."
Typically, experts estimate that between 70 and 90 percent of a population must be immune to a contagious disease to achieve herd immunity -- whether through vaccination or other exposure to an infection.
However, a recent study in Spain, one of the countries hardest-hit by the pandemic, found just five percent of those surveyed had coronavirus antibodies. On a regional basis, the percentage varied from fewer than three percent in coastal regions to more than 10 percent in areas around Madrid.
https://www.foxnews.com/health/clay-ackerly-coronavirus-herd-immuni...
"My patient caught Covid-19 twice. So long to herd immunity hopes?" (Vox, 7/12/20) - original article
Jul 15, 2020
Dr. Krishna Kumari Challa
Researchers discover how cells remember infections decades later
https://phys.org/news/2017-12-cells-infections-decades.html
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An exploding white dwarf star blasted itself out of its orbit with another star in a "partial supernova" and is now hurtling across our galaxy, according to a new study from the University of Warwick.
https://phys.org/news/2020-07-blast-star-hurtling-milky.html?utm_so...
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https://phys.org/news/2020-07-scientists-uncover-key-ribosomes-prot...
Scientists uncover key process in the manufacture of ribosomes and proteins
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Scientists discover heavy element chemistry can change at high pressures
New research shows that one of the heaviest known elements can be manipulated to a greater degree than previously thought, potentially paving the way for new strategies to recycle nuclear fuel and better long-term storage of radioactive elements.
https://phys.org/news/2020-07-fsu-news-scientists-heavy-element.htm...
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https://phys.org/news/2020-07-true-scientists-discuss-evolution-whi...
Scientists discuss evolution of white coloration of velvet ants
Jul 15, 2020
Dr. Krishna Kumari Challa
Bacteria with a metal diet discovered in dirty glassware
Microbiologists have discovered bacteria that feed on manganese and use the metal as their source of calories. Such microbes were predicted to exist over a century ago, but none had been found or described until now.
The study also reveals that the bacteria can use manganese to convert carbon dioxide into biomass, a process called chemosynthesis. Previously, researchers knew of bacteria and fungi that could oxidize manganese, or strip it of electrons.
Researchers found the bacteria serendipitously after performing unrelated experiments using a light, chalk-like form of manganese. They had left a glass jar soiled with the substance to soak in tap water in their office sink before departing for several months to work off campus. When they returned, the jar was coated with a dark material.
They wondered, 'What is that?' and systematically performed tests to figure that out.
The black coating was in fact oxidized manganese generated by newfound bacteria that had likely come from the tap water itself. There is evidence that relatives of these creatures reside in groundwater.
Manganese is one of the most abundant elements on the surface of the earth. Manganese oxides take the form of a dark, clumpy substance and are common in nature; they have been found in subsurface deposits and can also form in water-distribution systems.
There is a whole set of environmental engineering literature on drinking-water-distribution systems getting clogged by manganese oxides. But how and for what reason such material is generated there has remained an enigma. Clearly, many scientists have considered that bacteria using manganese for energy might be responsible, but evidence supporting this idea was not available until now.
The finding helps researchers better understand the geochemistry of groundwater. It is known that bacteria can degrade pollutants in groundwater, a process called bioremediation. When doing this, several key organisms will "reduce" manganese oxide, which means they donate electrons to it, in a manner similar to how humans use oxygen in the air. Scientists have wondered where the manganese oxide comes from in the first place.
The bacteria discovered now can produce it, thus they enjoy a lifestyle that also serves to supply the other microbes with what they need to perform reactions that we consider to be beneficial and desirable.
The research findings also have possible relevance to understanding manganese nodules that dot much of the seafloor.
Bacterial chemolithoautotrophy via manganese oxidation, Nature (2020). DOI: 10.1038/s41586-020-2468-5
https://phys.org/news/2020-07-bacteria-metal-diet-dirty-glassware.h...
Jul 16, 2020
Dr. Krishna Kumari Challa
Hallmark of severe COVID-19 patients identified
In analyzing blood, tissue, immune cells and other samples from the patients, the researchers came upon what they think is a signature for people with severe infections—a combination of an interferon response deficiency and exacerbated inflammation. They suggest the signature may represent a hallmark for severely ill COVID-19 patients. The researchers suggest their findings could lead to therapies that boost interferon response to an infection while also reducing inflammation.
More specifically, the researchers found that critically ill patients had a deficiency in the response of type I interferons—a kind of protein that is used by the immune system to fight infections. In addition, there were higher than normal levels of proinflammatory signaling. Together, the two responses left patients with little ammunition to fight their infections. The work builds on studies by other researchers finding that interferon signaling in infected areas may play a role in mitigating disease progression. Such work has shown that duration, timing and location of interferon exposure to the virus are critical factors that appear to underlie the degree of success with current therapies.
Jérôme Hadjadj et al, Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients, Science (2020). DOI: 10.1126/science.abc6027
https://medicalxpress.com/news/2020-07-hallmark-severe-covid-patien...
Jul 16, 2020
Dr. Krishna Kumari Challa
Invasive alien species may soon cause dramatic global biodiversity loss
An increase of 20 to 30 per cent of invasive non-native (alien) species would lead to dramatic future biodiversity loss worldwide. This is the conclusion of a study by an international team of researchers.
Human activities intentionally and unintentionally introduce more and more plant and animal species to new regions of the world—for example, via commodity transport or tourism.
Some of these alien species have negative consequences for biodiversity and humans well-being, for example by displacing native species or transmitting diseases. However, while we have relatively good information on the historical spread of alien species, there is still little knowledge about their future development.
The study shows that an increase of 20 to 30 per cent in the number of newly introduced alien species is considered sufficient to cause massive global biodiversity loss—a value that is likely to be reached soon, as the number of introduced species is constantly increasing.
humans are the main driver of the future spread of alien species. The experts identify three main reasons, primarily the increasing global transport of goods, followed by climate change and then the impacts of economic development such as energy consumption and land use. The study also shows that the spread of alien species can be greatly slowed down by ambitious countermeasures.
Franz Essl et al, Drivers of future alien species impacts: An expert‐based assessment, Global Change Biology (2020). DOI: 10.1111/gcb.15199
https://phys.org/news/2020-07-invasive-alien-species-global-biodive...
Jul 16, 2020
Dr. Krishna Kumari Challa
Researchers develop first of its kind, simple test for identifying toxic silver ions
https://phys.org/news/2020-07-kind-simple-toxic-silver-ions.html?ut...
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https://phys.org/news/2020-07-car-microplastics-ocean-thousands-mil...
How your car sheds microplastics into the ocean thousands of miles away
A new study has revealed that microplastics released from car tires and brake systems are a major source of marine plastic pollution
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https://phys.org/news/2020-07-cases-black-hole-mistaken-identity.ht...
Cases of black hole mistaken identity
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Researchers create a robotic camera backpack for insects
https://techxplore.com/news/2020-07-gopro-beetles-robotic-camera-ba...
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https://techxplore.com/news/2020-07-alexa-siri-cortana-private-conv...
Are Alexa, Siri, and Cortana recording your private conversations?
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“The world has now witnessed the compression of 6 years of work int...
The Covid-19 Vaccine-Development Multiverse
https://www.nejm.org/doi/full/10.1056/NEJMe2025111?utm_source=Natur...
Jul 16, 2020
Dr. Krishna Kumari Challa
How Galileo Battled the Science Deniers of His Time
The man who discovered Jupiter’s satellites and the mountains of the moon had no patience for idiots
https://www.scientificamerican.com/article/how-galileo-battled-the-...
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On Antarctica, humanity's small footprint has big impact
Humanity's accelerating impact on the vast wilderness of Antarctica extends well beyond scientific stations and eco-tourism along its fringes, both in scope and intensity, scientists warned
https://phys.org/news/2020-07-antarctica-humanity-small-footprint-b...
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Researchers find technique for 3-D printing on nanoscale that can correct mistakes
https://phys.org/news/2020-07-technique-d-nanoscale.html?utm_source...
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$$ Is psychiatry shrinking what’s considered normal?
https://theconversation.com/is-psychiatry-shrinking-whats-considere...
Jul 16, 2020
Dr. Krishna Kumari Challa
Palaeontologists Have Unearthed a Distinctive Hook-Clawed Dinosaur
https://www.sciencealert.com/paleontologists-have-unearthed-one-of-...
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https://www.sciencealert.com/for-the-first-time-scientists-have-com...
For The First Time, Scientists Have Completely Sequenced a Human Chromosome
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https://medicalxpress.com/news/2020-07-scientists-uncover-sars-cov-...
Scientists uncover SARS-CoV-2-specific T cell immunity in recovered COVID-19 and SARS patients
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https://phys.org/news/2020-07-devices-fibers-laundry.html?utm_sourc...
Using fiber-catching devices as part of the laundry process can dramatically reduce the amount of microscopic particles potentially entering the marine environment, according to new research.
Devices can reduce fibers produced in laundry cycle by up to 80%
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Blood vessels communicate with sensory neurons to decide their fate
Blood vessels communicate with sensory neurons to decide whether they remain as a reservoir of stem cells or differentiate
https://www.eurekalert.org/pub_releases/2020-07/upf--bvc071620.php
Jul 16, 2020
Dr. Krishna Kumari Challa
Decoding Butterfly Color
Scientists Modify Biology with Technology
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https://www.ted.com/talks/christina_agapakis_what_happens_when_biol...
Jul 16, 2020
Dr. Krishna Kumari Challa
Study reveals how a dangerous parasite controls its host cell to spread around the body
https://phys.org/news/2020-07-reveals-dangerous-parasite-host-cell....
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https://phys.org/news/2020-07-dietary-guidelines-compatible-global-...
Most dietary guidelines are not compatible with global health and environmental targets
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https://phys.org/news/2020-07-galaxies-die-insights-quenching-star....
How galaxies die: New insights into the quenching of star formation
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https://phys.org/news/2020-07-astronomers-black-hole-corona-reappea...
In a first, astronomers watch a black hole's corona disappear, then reappear
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https://www.eurekalert.org/pub_releases/2020-07/ou-ppr071420.php
In a random crossover trial, researchers were able to reduce phantom-limb pain after only three days of training with a brain-computer-interface
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https://www.sciencealert.com/some-masks-are-better-than-others-here...
The Best And Worst Face Masks For COVID-19, Ranked by Their Level of Protection
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Identified: Molecular Predictors of Rheumatoid Arthritis Relapse
The presence of a particular set of RNAs in the blood forewarns of an onset of severe symptoms and points to the cells involved.
https://www.the-scientist.com/news-opinion/identified-molecular-pre...
Jul 17, 2020
Dr. Krishna Kumari Challa
Siberia heat 'almost impossible' without climate change
A heatwave in Siberia that saw temperature records tumble as the region sweltered in 38-degree Celsius highs was "almost impossible" without the influence of manmade climate change, leading scientists said.
An international team of researchers found that the record-breaking warm period was more than 2C hotter than it would have been if humans had not warmed the planet through decades of greenhouse gas emissions.
This is further evidence of the extreme temperatures we can expect to see more frequently around the world in a warming climate.
https://phys.org/news/2020-07-siberia-impossible-climate.html?utm_s...
Jul 17, 2020
Dr. Krishna Kumari Challa
Immunity to COVID-19 may not last. This threatens a vaccine and herd immunity
An important new study released online this week could have a large bearing on how our future looks in 2021 and beyond.
It suggests our immunity to SARS-CoV-2 does not last very long at all — as little as two months for some people. If this is the case, it means a potential vaccine might require regular boosters, and herd immunity might not be viable at all.
https://theconversation.com/immunity-to-covid-19-may-not-last-this-...
Jul 17, 2020
Dr. Krishna Kumari Challa
Replacing lithium with sodium in batteries
An international team of scientists has found that instead of lithium (Li), sodium (Na) "stacked" in a special way can be used for battery production. Sodium batteries would be significantly cheaper and equivalently or even more capacious than existing lithium batteries.
https://phys.org/news/2020-07-lithium-sodium-batteries.html?utm_sou...
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Scientists achieve major breakthrough in preserving integrity of sound waves
In a breakthrough for physics and engineering, researchers have presented the first demonstration of topological order based on time modulations. This advancement allows the researchers to propagate sound waves along the boundaries of topological metamaterials without the risk of waves traveling backwards or being thwarted by material defects.
https://phys.org/news/2020-07-scientists-major-breakthrough.html?ut...
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https://phys.org/news/2020-07-power-toxic-dominance-groups.html?utm...
Dominance reduces influence in groups
dominant individuals can influence a group through force, but passive individuals are far better at bringing a group to consensus.
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https://phys.org/news/2020-07-chemical-thermometers-temperature-nan...
Chemical thermometers take temperature to the nanometric scale
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https://phys.org/news/2020-07-scientists-uncover-atomic-epstein-bar...
Scientists uncover first atomic structure of Epstein-Bar virus nucleocapsid
Jul 18, 2020
Dr. Krishna Kumari Challa
'Erasing' drug-associated memories may help prevent addiction relapse
https://medicalxpress.com/news/2020-07-erasing-drug-associated-memo...
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Blood test detects positive COVID-19 result in 20 minutes
https://medicalxpress.com/news/2020-07-blood-positive-covid-result-...
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Atomtronic device could probe boundary between quantum, everyday worlds
https://phys.org/news/2020-07-atomtronic-device-probe-boundary-quan...
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https://phys.org/news/2020-07-hairpin-vortices-supersonic-turbulenc...
Study confirms hairpin vortices in supersonic turbulence
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**Measuring drug-induced molecular changes within a cell at sub-wavelength scale
https://phys.org/news/2020-07-drug-induced-molecular-cell-sub-wavel...
Jul 18, 2020
Dr. Krishna Kumari Challa
Sperm discovery reveals clue to genetic 'immortality'
New insights into an elusive process that protects developing sperm cells from damage in growing embryos, sheds light on how genetic information passes down, uninterrupted, through generations.
The study identified a protein, known as SPOCD1, which plays a key role in protecting the early-stage precursors to sperm, known as germ cells, from damage in a developing embryo.
During their development, germ cells undergo a reprogramming process that leaves them vulnerable to rogue genes, known as jumping genes, which can damage their DNA and lead to infertility.
Reprogramming is essential for correct germ cell development in embryos, but leaves them temporarily vulnerable to a subset their own genes, known as jumping genes, that threaten genetic chaos.
Evading such damage allows germ cells to become the pool of self-renewing cells that produce healthy sperm throughout adult life.
Germ cells are the vital link between generations but they need unique strategies to protect the genetic information they carry, so it can be passed successfully from parents to their offspring.
The study is the first to reveal the role of the SPOCD1 protein, which helps to recruit protective chemical tags, known as DNA methylations, to disable jumping genes.
Scientists have long puzzled over how germ cells escape damage during the reprogramming process, as it temporarily wipes their genetic slate clean of existing protective tags.
"The identification of SPOCD1 finally opens the doors to further investigation that will give a more elaborate understanding of this elusive process and male fertility.
Tests in male mice revealed that loss of this protein leads to infertility because the DNA methylation process does not happen correctly, allowing jumping genes to damage the developing sperms' DNA.
Jumping genes make up over half of our DNA and move around the genome controlling how our genes are used. But their activity needs to be carefully regulated to avoid them causing damage.
The team discovered that early sperm's secret line of defence is activated when SPOCD1 binds with another protein, known as MIWI2, which is already known to have a role in silencing jumping genes.
Previous studies revealed that MIWI2 protein is bound to small molecules, known as piRNAs, that play a key role in disabling jumping genes through DNA methylation.
Ansgar Zoch et al. SPOCD1 is an essential executor of piRNA-directed de novo DNA methylation, Nature (2020). DOI: 10.1038/s41586-020-2557-5
https://phys.org/news/2020-07-sperm-discovery-reveals-clue-genetic....
Jul 18, 2020
Dr. Krishna Kumari Challa
New insight into the origin of water on the earth
https://phys.org/news/2020-07-insight-earth.html?utm_source=nwlette...
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Cancer-causing dust released by earthworks
Tiny, needle-like fibers that can become airborne if bedrock is disturbed during earthworks has the potential to cause asbestos-type disease and should be investigated, scientists say.
https://phys.org/news/2020-07-cancer-causing-earthworks.html?utm_so...
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Enhanced water repellent surfaces discovered in nature
https://phys.org/news/2020-07-repellent-surfaces-nature.html?utm_so...
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https://phys.org/news/2020-07-airplanes.html?utm_source=nwletter&am...
What if airplanes could repair their own damage?
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New explosive materials to bring nontoxic ammunition
https://phys.org/news/2020-07-explosive-materials-nontoxic-ammuniti...
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https://www.sciencefocus.com/future-technology/cryonics-could-you-l...
Cryonics: Could you live forever?
A new facility will store tens of thousands of cryogenically-frozen people. The hope is to one day bring them back to life, but just how realistic are its aims?
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https://phys.org/news/2020-07-chemistry-d-transition-metal-carbides...
Researchers discover new chemistry of 2-D transition metal carbides and carbonitrides
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https://phys.org/news/2020-07-rainbow-pace.html?utm_source=nwletter...
A walk through the rainbow with PACE
Jul 18, 2020
Dr. Krishna Kumari Challa
For The First Time, Human Cartilage Has Been Engineered in Space
https://www.sciencealert.com/for-the-first-time-human-cartilage-has...
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Scientific evidence: Ancient Teeth Show 'Invasion' of Egypt 3,600 Years Ago Was No Invasion at All
https://www.sciencealert.com/archaeologists-think-the-foreign-invas...
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https://www.sciencealert.com/here-s-why-our-mind-s-eye-sees-the-wor...
Brain Scans Show Why Our Mind's Eye Sees The World So Differently to Everyday Vision
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https://www.eurekalert.org/pub_releases/2020-07/uoc-sss071620.php
Scientists supercharge shellfish to tackle vitamin deficiency in humans
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$$ https://phys.org/news/2020-07-dogs-earth-magnetic-field.html?utm_so...
How can lost dogs return to their homes?
Dogs may use Earth's magnetic field to navigate
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https://phys.org/news/2020-07-exhaled-biomarkers-reveal-lung-diseas...
Exhaled biomarkers can reveal lung disease
Jul 18, 2020
Dr. Krishna Kumari Challa
What’s the difference between a scientific law and theory?
Jul 20, 2020
Dr. Krishna Kumari Challa
Scientists achieve first complete assembly of human X chromosome
https://phys.org/news/2020-07-scientists-human-chromosome.html?utm_...
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Herd immunity: why the figure is always a bit vague
https://theconversation.com/herd-immunity-why-the-figure-is-always-...
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https://phys.org/news/2020-07-scientists-volcanoes-venus.html?utm_s...
Scientists discover volcanoes on Venus are still active
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Cacti and other iconic desert plants threatened by solar development
https://phys.org/news/2020-07-cacti-iconic-threatened-solar.html?ut...
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https://phys.org/news/2020-07-covid-viral-shutdown-protein-synthesi...
COVID-19: Viral shutdown of protein synthesis method found
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https://phys.org/news/2020-07-astrophysicists-billion-years-univers...
Astrophysicists fill in 11 billion years of the universe's expansion history
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Jul 20, 2020
Dr. Krishna Kumari Challa
Study reveals strange magnetic behaviour 8-11 million years ago
Research has revealed that strange behaviour of the magnetic field in the South Atlantic region existed as far back as eight to 11 million years ago, suggesting that today's South Atlantic Anomaly is a recurring feature and unlikely to represent an impending reversal of the Earth's magnetic field.
The South Atlantic Anomaly is an area characterized by a significant reduction in the strength of Earth's magnetic field compared with areas at similar geographic latitudes. Here, protection from harmful radiation from space is reduced. The most significant signs of this are technical malfunctions aboard satellites and spacecraft.
The geomagnetic records from the rocks covering 34 different volcanic eruptions that took place between eight and 11 million years ago revealed that at these occurrences the direction of the magnetic field for St Helena often pointed far from the North pole, just like it does today.
The Earth's magnetic field, or the geomagnetic field, not only gives us the ability of navigating with a compass, but also protects our atmosphere from charged particles coming from the sun, called solar wind. However, it is not completely stable in strength and direction, both over time and space, and it has the ability to completely flip or reverse itself with substantial implications.
The South Atlantic Anomaly is a topic of debate between scientists in this field. Besides the fact that it causes damages to space technology, it also raises the question of where it comes from and whether it represents the start of the total weakening of the field and a possible upcoming pole reversal.
study provides the first long term analysis of the magnetic field in this region dating back millions of years. It reveals that the anomaly in the magnetic field in the South Atlantic is not a one-off, similar anomalies existed eight to 11 million years ago.
"This is the first time that the irregular behaviour of the geomagnetic field in the South Atlantic region has been shown on such a long timescale. It suggests that the South Atlantic Anomaly is a recurring feature and probably not a sign of an impending reversal.
"It also supports earlier studies that hint towards a link between the South Atlantic Anomaly and anomalous seismic features in the lowermost mantle and the outer core. This brings us closer to linking behaviour of the geomagnetic field directly to features of the Earth's interior"
Elevated paleomagnetic dispersion at Saint Helena suggests long-lived anomalous behavior in the South Atlantic, Proceedings of the National Academy of Sciences (2020). DOI: 10.1073/pnas.2001217117
https://phys.org/news/2020-07-reveals-strange-magnetic-behaviour-.h...
Jul 21, 2020
Dr. Krishna Kumari Challa
Using drones to reduce disease-spreading mosquito populations
Vector-borne diseases are illnesses that can be transmitted to humans by blood-feeding insects, such as mosquitoes, ticks and fleas. Mosquitoes are known to contribute to the spread of a number of vector-borne diseases, including malaria, dengue, yellow fever and Zika.
According to the World Health Organization (WHO), this class of diseases accounts for 17% of all infectious diseases in the world, causing over 1 million human deaths per year. Developing methods to reduce the spread and prevalence of these diseases is thus of utmost importance, as it could ultimately save countless human lives.
In recent years, scientists have devised a number of control methods to reduce or manage harmful insect populations without injecting harmful chemicals into the environment. One of these methods is the sterile insect technique (SIT), a form of insect birth control that entails the use of radiation to sterilize male mosquitoes, which are then released into the air in a target area and start mating with wild female insects.
As a sterile male and a fertile female do not produce any offspring after they mate, SIT produces a decline in the insect population. In order to reduce the incidence of vector-borne diseases, however, large amounts of good quality sterile insects need to be released continuously over affected geographical areas. Techniques for the cost-effective aerial release of sterile mosquitoes over extended geographical regions are thus a bottleneck to enabling the application of SIT on a large scale.
Researchers have recently developed a system to apply the SIT using unmanned aerial vehicles (UAVs), or drones, to manage and reduce vector-borne-disease-transmitting mosquito populations. This unique system entails the release of sterile mosquitoes in the air over large geographical areas using UAVs or drones. The system, tested in Brazil, enabled a uniform dispersal of sterile male Aedes aegypti mosquitoes while maintaining their quality, leading to a consistent sterile-to-wild male ratio.
The key goal of the study was to measure the survival, dispersal and sexual competitiveness of sterile male mosquitoes after they were mass-produced, sorted, handled, irradiated, marked and released within a geographical area using UAVs. The UAV-based release system they devised uses a canister in which mosquitoes are chilled down to 8-12 °C and compacted. Each canister can contain up to 50,000 sterile males. When the canister opens, the mosquitoes fall into a rotating cylinder that releases them into the open air with each of its rotations. The rotation speed controls the number of sterile males released per minute. It is fully automated, and release rates can be controlled depending on the location and speed of the drone.
J. Bouyer et al. Field performance of sterile male mosquitoes released from an uncrewed aerial vehicle, Science Robotics (2020). DOI: 10.1126/scirobotics.aba6251
https://techxplore.com/news/2020-07-drones-disease-spreading-mosqui...
Jul 21, 2020
Dr. Krishna Kumari Challa
Poisons used to make food more beautiful, last longer
https://www.scidev.net/global/health/feature/poisons-used-to-make-f...
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Oh No, Salmonella Has Found a Way to Avoid Being Washed Off Our Salads
Some Salmonella bacteria strains have found a way of evading plant defences and sneaking their way into leafy greens – a strategy that's effective enough to protect them against plant immune systems and from being washed off in the kitchen.
https://www.sciencealert.com/salmonella-sneaks-into-plant-air-holes...
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Even People With Mild COVID-19 Symptoms Are Experiencing Long-Term Fatigue
https://www.sciencealert.com/why-are-some-people-experiencing-long-...
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https://www.the-scientist.com/news-opinion/could-covid-19-trigger-c...
Could COVID-19 Trigger Chronic Disease in Some People?
A handful of viruses have been associated with long-term, debilitating symptoms in a subset of those who become infected. Early signs hint that SARS-CoV-2 may do the same.
Jul 21, 2020
Dr. Krishna Kumari Challa
Interaction dynamics between designer microrobots and the immune system
https://medicalxpress.com/news/2020-07-interaction-dynamics-microro...
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https://phys.org/news/2020-07-unparalleled-human-gut-ecosystem.html...
Inventory of the human gut ecosystem: An international team of scientists has collated all known bacterial genomes from the human gut microbiome into a single large database, allowing researchers to explore the links between bacterial genes and proteins, and their effects on human health.
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https://medicalxpress.com/news/2020-07-chronic-inflammation-evoluti...
Chronic inflammation alters the evolution of cells in the colon, study finds: researchers have compared diseased colon with healthy tissue to better understand how inflammatory bowel disease (IBD) is linked to an increased risk of colorectal cancers, at a molecular level.
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https://phys.org/news/2020-07-artificial-cells-viruses-safe.html?ut...
Artificial cells produce parts of viruses for safe studies
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https://phys.org/news/2020-07-physicists-ways-gamma.html?utm_source...
Physicists find ways to control gamma radiation: by means of acoustics.
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https://phys.org/news/2020-07-carbon-footprint.html?utm_source=nwle...
New model proposed to reduce carbon footprint
New model proposed to reduce carbon footprint: to bring the carbon footprint of international conferences down. The model can apply to small regional conferences as well. The model identifies three key areas for action; carefully selecting venues to minimize transport emissions, hosting conferences every second year to instantly cut travel by 50%, and creating hubs so people travel shorter distances to still benefit from networking while linking virtually to other hubs.
Jul 22, 2020
Dr. Krishna Kumari Challa
Gamma-ray telescopes measure diameters of distant stars
https://phys.org/news/2020-07-gamma-ray-telescopes-diameters-distan...
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https://phys.org/news/2020-07-comprehensive-description-human-tissu...
A comprehensive description of the human tissue virome in healthy individuals
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https://phys.org/news/2020-07-viruses-bacteria-gut-microbiome.html?...
How viruses and bacteria balance each other in the gut microbiome
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https://theconversation.com/what-makes-people-switch-to-reusable-cu...
What makes people switch to reusable cups? It’s not discounts, it’s what others do
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https://www.sciencealert.com/astrophysicists-unveil-biggest-ever-3d...
Scientists Just Revealed The Largest-Ever 3D Map of The Universe
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Jul 22, 2020
Dr. Krishna Kumari Challa
Proteins—and labs—coming together to prevent Rett syndrome
https://phys.org/news/2020-07-proteinsand-labscoming-rett-syndrome....
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https://phys.org/news/2020-07-chemists-tough-plastics-recyclable.ht...
Chemists make tough plastics recyclable
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Diamonds shine a light on hidden currents in graphene
https://phys.org/news/2020-07-diamonds-hidden-currents-graphene.htm...
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Mapping the brain's sensory gatekeeper
https://medicalxpress.com/news/2020-07-brain-sensory-gatekeeper.htm...
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https://phys.org/news/2020-07-image-multi-planet-sun-like-star.html...
First image of a multi-planet system around a sun-like star
Jul 23, 2020
Dr. Krishna Kumari Challa
Genomic basis of bat superpowers revealed: Like how they survive deadly viruses
The genetic material that codes for bat adaptations and superpowers—such as the ability to fly, to use sound to move effortlessly in complete darkness, to tolerate and survive potentially deadly viruses, and to resist aging and cancer—has been revealed and published.
One aspect of the paper findings shows evolution through gene expansion and loss in a family of genes, APOBEC3, which is known to play an important role in immunity to viruses in other mammals. The details in the paper that explain this evolution set the groundwork for investigating how these genetic changes, found in bats but not in other mammals, could help prevent the worst outcomes of viral diseases in other mammals, including humans.
The team compared these bat genomes against 42 other mammals to address the unresolved question of where bats are located within the mammalian tree of life. Using novel phylogenetic methods and comprehensive molecular data sets, the team found the strongest support for bats being most closely related to a group called Fereuungulata that consists of carnivorans (which includes dogs, cats and seals, among other species), pangolins, whales and ungulates (hooved mammals).
To uncover genomic changes that contribute to the unique adaptations found in bats, the team systematically searched for gene differences between bats and other mammals, identifying regions of the genome that have evolved differently in bats and the loss and gain of genes that may drive bats' unique traits
The researchers found evidence the exquisite genomes revealed "fossilized viruses," evidence of surviving past viral infections, and showed that bat genomes contained a higher diversity of these viral remnants than other species providing a genomic record of ancient historical interaction with viral infections. The genomes also revealed the signatures of many other genetic elements besides ancient viral insertions, including 'jumping genes' or transposable elements.
Six reference-quality genomes reveal evolution of bat adaptations, Nature (2020). DOI: 10.1038/s41586-020-2486-3
https://phys.org/news/2020-07-genomic-basis-superpowers-revealed-su...
Jul 23, 2020
Dr. Krishna Kumari Challa
Researchers diffract a beam of organic molecules
A team of researchers has succeeded in diffracting a beam of organic molecules. In their paper published in the journal Physical Review Letters, the researchers describe demonstrating Bragg diffraction of the molecules ciprofloxacin and phthalocyanine.
Over the long history of wave-particle research, scientists have found that light is both a wave and a particle. They have also shown that electrons have a similar wave-particle duality. Physicists theorize that wave-particle duality is a fundamental feature of the universe. This suggests that all matter should have wave-like phenomena, which means that it should be able to behave in ways that are similar to light and electrons. As one example, it should be possible to demonstrate interference and diffraction of matter, such as whole molecules. In this new effort, the researchers have done exactly that by demonstrating a type of diffraction pattern with molecules of ciprofloxacin (an antibiotic) and phthalocyanine (a kind of dye).
The work involved firing a laser beam at a sheet of glass upon which the ciprofloxacin and phthalocyanine molecules were applied, forcing them to fly off the glass at a very rapid speed. The molecules flew toward a barrier with a vertical slit that allowed only those molecules traveling in the desired direction to pass through. Those that passed through were met by another laser beam focused with a standing wave pattern. The high-intensity parts of the beam deflected the molecules in a way akin to passing through a gap, which led to the creation of a diffraction pattern. The molecules were then directed through another slit and immediately thereafter impacted a flat screen, where they adhered. And because the types of molecules the researchers chose for the experiment glow when exposed to UV or blue light, the researchers were able to see them. By running the experiment for a short period of time, the researchers were able to observe a pattern appear on the screen—evidence of a diffraction pattern.
The researchers were able to create different patterns by using different initial laser velocities and different incident angles. They note also that the patterns were weak, though still observable, and agreed with theory.
Sophia Chen. Defracting a Beam of Organic Molecules, Physics (2020). DOI: 10.1103/Physics.13.s93
https://phys.org/news/2020-07-diffract-molecules.html?utm_source=nw...
Jul 23, 2020
Dr. Krishna Kumari Challa
'Seeing' and 'manipulating' functions of living cells
https://phys.org/news/2020-07-functions-cells.html?utm_source=nwlet...
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https://phys.org/news/2020-07-leak-sea-bed-methane-antarctica.html?...
Active leak of sea-bed methane discovered in Antarctica for first time
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https://phys.org/news/2020-07-evidence-hormone-disruptor-chemical-t...
Evidence of "hormone disruptor" chemical threats grows
A growing number of chemicals in pesticides, flame retardants, and certain plastics have been linked to widespread health problems including infertility, diabetes, and impaired brain development, a set of reviews of hundreds of studies concludes.
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https://phys.org/news/2020-07-toxic-wildfire-ages.html?utm_source=n...
'Four times more toxic': How wildfire smoke ages over time
Enormous plumes of smoke thrown into the atmosphere by uncontrolled wildfires may be affecting the health of people living hundreds of miles away.
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https://phys.org/news/2020-07-unique-narrow-wavebands-uv-germs.html...
Researchers describe unique system for testing how well narrow wavebands of UV light kill germs
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https://phys.org/news/2020-07-cells.html?utm_source=nwletter&ut...
Cells communicate by doing the 'wave'
Jul 23, 2020
Dr. Krishna Kumari Challa
https://theconversation.com/bacteria-and-viruses-are-travelling-the...
Bacteria and viruses are travelling the world on highways in the sky
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** Chronic fatigue syndrome may hold keys to understanding post-Covid syndrome
https://www.statnews.com/2020/07/21/chronic-fatigue-syndrome-keys-u...
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https://www.sciencealert.com/new-study-says-a-blood-test-can-find-5...
New Blood Test Detects 5 Types of Cancer Years Before Standard Diagnosis
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https://www.scientificamerican.com/article/quantum-tunneling-is-not...
Quantum Tunneling Is Not Instantaneous, Physicists Show
A new experiment tracks the transit time of particles burrowing through barriers, revealing previously unknown details of a deeply counterintuitive phenomenon
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** New research identifies the rules that termites use to build their nests
https://phys.org/news/2020-07-termites.html?utm_source=nwletter&...
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https://www.the-scientist.com/notebook/fly-colonies-help-calculate-...
Forensic science: Fly Colonies Help Calculate Time of Death of Car Trunk Cadavers
Using pigs as human proxies, forensic entomologists reveal how bodies in vehicles decompose differently from those dumped outside.
Jul 23, 2020
Dr. Krishna Kumari Challa
COVID-19 lockdown caused 50% global reduction in human-linked Earth vibrations
https://phys.org/news/2020-07-covid-lockdown-global-reduction-human...
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https://phys.org/news/2020-07-scientists-topological-magnet-exotic-...
Scientists discover a topological magnet that exhibits exotic quantum effects
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https://phys.org/news/2020-07-technique-capture-carbon-dioxide-grea...
New technique to capture carbon dioxide could greatly reduce power plant greenhouse gases
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https://phys.org/news/2020-07-quantum-physicists-mystery-strange-me...
Quantum physicists crack mystery of 'strange metals,' a new state of matter
Measuring how long quantum tunneling takes
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https://phys.org/news/2020-07-physicists-technology-microwaves-opti...
Physicists develop technology to transform information from microwaves to optical light
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https://phys.org/news/2020-07-biologists-cells-resources.html?utm_s...
Biologists shed light on how cells move resources
Jul 24, 2020
Dr. Krishna Kumari Challa
Dark energy: map gives clue about what it is – but deepens dispute about the cosmic expansion rate
https://theconversation.com/dark-energy-map-gives-clue-about-what-i...
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https://techxplore.com/news/2020-07-laughter-unique-biometric-signa...
Laughter as a unique biometric signature
The popular view of biometric security often invokes fingerprint readers, iris or retinal scans, and voice-activated systems. However, any unique human characteristic whether the shape of one's ears, the whole face, the pattern of blood vessels in the back of the hand, walking pattern, heart rhythm or even how one types at a keyboard, might be used to provide a secure signature of login. Some traits are easier to analyze than others and some, such as fingerprints, can be spoofed.
Research published in the International Journal of Biometrics has taken an amusing trait to demonstrate how the way a person laughs might be used in biometrics.
people can recognize other people by the unique nature of their laughter, perhaps in an even more obvious way than their voice. Moreover, while many people are adept at impersonating the voices of other people, mimicking someone's laugh is far more difficult. The team has now used statistical analyses of the various audible frequencies present in a person's laugh to create a digital signature for each unique laugh.
Tests on the approach show their prototype recognition algorithm to be 90 percent accurate, which compares very favorably with the 65% accuracy of a conventional Gaussian model. However, combining their algorithm with the Gaussian approach can boost accuracy overall by more than 5 percent.
Comfort Oluwaseyi Folorunso et al. Laughter signature: a novel biometric trait for person identification, International Journal of Biometrics (2020). DOI: 10.1504/IJBM.2020.108480
Jul 24, 2020
Dr. Krishna Kumari Challa
Mammal cells could struggle to fight space germs
https://phys.org/news/2020-07-mammal-cells-struggle-space-germs.htm...
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https://phys.org/news/2020-07-lightning-million-year-tropics.html?u...
estimate that more than 100 million lighting strikes on land each year will radically alter forests and other ecosystems in the region between the Tropic of Cancer and the Tropic of Capricorn.
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https://phys.org/news/2020-07-mosquitoes-human-blood-future.html?ut...
How mosquitoes got their taste for human blood and what it means for the future
Of about 3,500 mosquito species around the world, only a few have taken to specifically targeting people for biting, making them important spreaders of infectious diseases. To predict and help control the spread of those mosquito-borne illnesses, it's important to know where and why, evolutionarily speaking, certain mosquitoes got their taste for biting humans in the first place. Now, researchers reporting in the journal Current Biology on July 23 have identified two major factors: a dry climate and city life. Based on these findings, they predict that increased urbanization in the coming decades will mean even more human-biting mosquitoes in the future. They
found that in their native range of sub-Saharan Africa, they show extremely variable attraction to human hosts, ranging from strong preference for humans to strong preference for non-human animals."
"Mosquitoes living near dense human populations in cities such as Kumasi, Ghana, or Ouagadougou, Burkina Faso, showed increased willingness to bite human hosts," adds Noah Rose, also of Princeton. "But they only evolve a strong preference for human hosts in places with intense dry seasons—in particular, in the Sahel region, where rainfall is concentrated in just a couple months out of the year. We think this is because mosquitoes in these climates are especially dependent on humans and human water storage for their life cycle."
Noah H. Rose et al, Climate and Urbanization Drive Mosquito Preference for Humans, Current Biology (2020). DOI: 10.1016/j.cub.2020.06.092
Jul 24, 2020
Dr. Krishna Kumari Challa
https://theconversation.com/as-if-space-wasnt-dangerous-enough-bact...
bacteria become more deadly in microgravity
Worryingly, research from space flight missions has shown bacteria become more deadly and resilient when exposed to microgravity (when only tiny gravitational forces are present).
In space, bacteria seem to become more resistant to antibiotics and more lethal. They also stay this way for a short time after returning to Earth, compared with bacteria that never left Earth.
Adding to that, bacteria also seem to mutate quicker in space. However, these mutations are predominately for the bacteria to adapt to the new environment – not to become super deadly.
More research is needed to examine whether such adaptations do, in fact, allow the bacteria to cause more disease.
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https://theconversation.com/the-ten-factors-linked-to-increased-ris...
The ten factors linked to increased risk of Alzheimer’s disease
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https://www.acsh.org/news/2020/07/21/science-communicators-are-rout...
** Science Communicators Are Routinely Lied About, Harassed, Threatened
Jul 24, 2020
Dr. Krishna Kumari Challa
How to stop your glasses from fogging up while wearing a face mask
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**How Does Caffeine Affect Sleep?
https://www.ted.com/talks/matt_walker_how_caffeine_and_alcohol_affe...
Jul 24, 2020
Dr. Krishna Kumari Challa
Experts Provide Tips on How to Wear a Mask Without Fogging Glasses or Short Breath
https://www.sciencealert.com/experts-provide-tips-on-how-to-wear-a-...
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L-type calcium channel blockers may contribute to heart failure, study finds
L-type calcium channel blockers (LCCBs)—the most widely used drugs for treating hypertension—may harm the heart as much as help it, according to a new study.
https://medicalxpress.com/news/2020-07-l-type-calcium-channel-block...
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https://medicalxpress.com/news/2020-07-drug-delivery-particles-neur...
Novel drug delivery particles use neurotransmitters as a 'passport' into the brain
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https://medicalxpress.com/news/2020-07-coronavirus-cells-1.html?utm...
Coronavirus makes changes that cause cells not to recognize it
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**
Genetic mutations help super bug become highly resistant to antibiotics
https://phys.org/news/2020-07-genetic-mutations-super-bug-highly.ht...
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https://phys.org/news/2020-07-scientists-key-restricting-antibiotic...
Scientists discover key to restricting antibiotic resistant bacteria
Jul 24, 2020
Dr. Krishna Kumari Challa
Coronavirus makes changes that cause cells not to recognize it
With an alarm code, we can enter a building without bells going off. It turns out that the SARS coronavirus 2 (SARS-CoV-2) has the same advantage entering cells. It possesses the code to waltz right in.
How can the coronavirus achieves this?
The scientists resolved the structure of an enzyme called nsp16, which the virus produces and then uses to modify its messenger RNA cap. It's a camouflage. Because of the modifications, which fool the cell, the resulting viral messenger RNA is now considered as part of the cell's own code and not foreign.
How do scientists overcome this?
Deciphering the 3-D structure of nsp16 paves the way for rational design of antiviral drugs for COVID-19 and other emerging coronavirus infections. The drugs, new small molecules, would inhibit nsp16 from making the modifications. The immune system would then pounce on the invading virus, recognizing it as foreign.
Structural basis of RNA cap modification by SARS-CoV-2, Nature Communications (2020). DOI: 10.1038/s41467-020-17496-8
https://medicalxpress.com/news/2020-07-coronavirus-cells-1.html?utm...
Jul 25, 2020
Dr. Krishna Kumari Challa
Neanderthal gene linked to increased pain sensitivity
Source: Neanderthal gene linked to increased pain sensitivity
https://www.nature.com/articles/d41586-020-02202-x?utm_source=Natur...
Jul 25, 2020
Dr. Krishna Kumari Challa
Quantum Tunneling Is Not Instantaneous, Physicists Show
A new experiment tracks the transit time of particles burrowing through barriers, revealing previously unknown details of a deeply counterintuitive phenomenon
https://www.scientificamerican.com/article/quantum-tunneling-is-not...
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How the Bits of Quantum Gravity Can Buzz
Where there’s cattle ranching and soybean farming, there’s fire, study finds
https://news.mongabay.com/2020/07/where-theres-cattle-ranching-and-...
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US Just Unveiled Its Blueprint For a "Virtually Unhackable" Quantum Internet
https://www.sciencealert.com/us-begins-planning-for-a-virtually-unh...
Jul 25, 2020
Dr. Krishna Kumari Challa
In cell studies, seaweed extract outperforms remdesivir in blocking COVID-19 virus
Heparin, a common anitcoagulent, could also form basis of a viral trap for SARS-CoV-2
In a test of antiviral effectiveness against the virus that causes COVID-19, an extract from edible seaweeds substantially outperformed remdesivir, the current standard antiviral used to combat the disease.
https://www.sciencedaily.com/releases/2020/07/200724104228.htm
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How COVID-19 Causes Loss of Smell
Olfactory support cells, not neurons, are vulnerable to novel coronavirus infection
https://hms.harvard.edu/news/how-covid-19-causes-loss-smell
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https://news.ucr.edu/articles/2020/07/24/neurons-are-genetically-pr...
Neurons are genetically programmed to have long lives
UC Riverside-led study identifies mechanism that prevents death of neurons
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Drug ingredients considered inert might have biological activity
Systematic investigation of excipients reveals that most are inactive, but a few may act upon biological targets
https://cen.acs.org/pharmaceuticals/Drug-ingredients-considered-ine...
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https://www.sciencealert.com/chemists-have-worked-out-how-to-make-t...
Chemists Just Worked Out How to Recycle Some of Our Toughest Single-Use Plastics
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Jul 26, 2020
Dr. Krishna Kumari Challa
How to test whether your home made face mask works properly or not
https://theconversation.com/does-your-homemade-mask-work-142675
To get an idea of how much this might happen, a simple test involving trying to blow out a candle directly in front of the wearer could be tried. Initially, the distance coupled with the strength of exhalation could be investigated, but then face coverings made from different materials and critically with different numbers of layers could be tried. The design of face covering that made it hardest to divert the candle flame will probably provide the best barrier for projecting the virus forward and through the face covering.
Jul 26, 2020
Dr. Krishna Kumari Challa
To prevent the next pandemic, we might need to cut down fewer trees
Study weighs costs of reducing virus spillover from animals against the toll of disease outbreak
https://www.sciencenews.org/article/coronavirus-covid-19-pandemic-p...
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https://phys.org/news/2020-07-phage-therapy-potential-prosthetic-jo...
Phage therapy shows potential for treating prosthetic joint infections
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https://www.sciencealert.com/physicists-find-a-new-way-to-show-mass...
Physicists Find a New Way to Reveal The Strange, Wave-Like Nature of Massive Molecules
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https://www.wsj.com/articles/sunscreen-chemicals-accumulate-in-body...
Sunscreen Chemicals Accumulate in Body at High Levels
Jul 27, 2020
Dr. Krishna Kumari Challa
Seismic waves help scientists 'see' chemical changes beneath a watershed
https://phys.org/news/2020-07-seismic-scientists-chemical-beneath-w...
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Designer nanozymes for reactive-oxygen species scavenging anti-inflammatory therapy
https://phys.org/news/2020-07-nanozymes-reactive-oxygen-species-sca...
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https://phys.org/news/2020-07-high-capacity-oil-adsorbing-mats-depl...
High-capacity oil-adsorbing mats could be deployed in oil spill emergencies to limit ecological damage
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https://phys.org/news/2020-07-scientists-publish-seminal-impact-nan...
Scientists publish seminal study into impact of nanoparticles on living species
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https://phys.org/news/2020-07-strategy-therapies-brain.html?utm_sou...
Developing a new strategy to selectively deliver therapies to the brain
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https://physicsworld.com/a/earths-atmosphere-rings-like-a-giant-bel...
Earth’s atmosphere rings like a giant bell, say researchers
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https://elifesciences.org/articles/60080?utm_source=content_alert&a...
Meta-Research: The growth of acronyms in the scientific literature
Abstract
Some acronyms are useful and are widely understood, but many of the acronyms used in scientific papers hinder understanding and contribute to the increasing fragmentation of science. Here we report the results of an analysis of more than 24 million article titles and 18 million article abstracts published between 1950 and 2019. There was at least one acronym in 19% of the titles and 73% of the abstracts. Acronym use has also increased over time, but the re-use of acronyms has declined. We found that from more than one million unique acronyms in our data, just over 2,000 (0.2%) were used regularly, and most acronyms (79%) appeared fewer than 10 times. Acronyms are not the biggest current problem in science communication, but reducing their use is a simple change that would help readers and potentially increase the value of science.
Jul 28, 2020
Dr. Krishna Kumari Challa
Psychologists show that embedding primes in a person's speech can influence people's decision making
psychologists found that embedding primes in a person's speech and gestures can influence people's decision-making
In both psychology and magic circles, primes are known as actions or words that unconsciously influence the thinking of another person One example is a policeman interrogating a witness tapping his ring while inquiring about jewelry a suspect might have been wearing. It is a technique magicians have used for years. They prime a person or audience by giving them subtle verbal or physical clues to get them to choose a number during a guessing trick, or a card during a card trick. In this new effort, the researchers tested the practice to see if it actually works.
The experiments involved asking volunteers to watch a live or taped performance of a person who, unbeknownst to them, was trying to prime them. The research began with 90 volunteers who were split into two groups. One group watched Pailhès (who is also an amateur magician) perform a live magic act—the other group watched a video version of the same act on a laptop. The act consisted of attempting to get the crowd of observers to pick a predesignated card—the three of diamonds.
As part of the routine, she mimicked an act by British illusionist Derren Brown in which he asks a member of the crowd to mentally transmit the correct card to the others in the crowd. He also asks the crowd to think about a bright, vivid colored card (more descriptive of a red card than a black one). He also mimes the shape of a diamond with his hands and asks the audience to think of the little numbers at the corners (ruling out double digits and face cards) and even draws the number "3" in the air with his hands—and asks the audience to imagine things in the middle as he says, "boom, boom, boom."
After mimicking this act, the researchers asked the audience members to write down a card by suit and number, which they turned in. Inspection of the cards showed that 17.8 percent of the audience members chose the three of diamonds—38.9 percent chose a three of any suit and 33.3 percent chose a diamond of any number, results that were far better than chance.
Alice Pailhès et al. Influencing choices with conversational primes: How a magic trick unconsciously influences card choices, Proceedings of the National Academy of Sciences (2020). DOI: 10.1073/pnas.2000682117
https://medicalxpress.com/news/2020-07-psychologists-embedding-prim...
Jul 28, 2020
Dr. Krishna Kumari Challa
Researchers create 'decoy' coatings that trick infrared cameras
Light can sometimes play tricks on our eyes. If you look at a shiny surface, what you see will largely depend on the surrounding environment and lighting conditions.
Researchers have now taken ocular distortion a step further, finding a way to imbed visual "decoys" into surfaces of objects in a way that can fool people into thinking they detect a specific image in the infrared that actually isn't there.
Infrared light is invisible to the human eye, but can be detected by a range of devices, such as night-vision goggles and thermal-imaging cameras. In this work,researchers can effectively tune target objects into emitting the same infrared radiation as the surrounding environment, making them invisible to infrared detection devices.
But what makes the researchers' work particularly novel is that they can manipulate the coatings in a way that a person trying to view the object with such a device would instead see a false image.
"This structure offers a general platform for unprecedented manipulation and processing of infrared signals.
this method provides better, more consistent camouflage because the product is mechanically flexible, power free and inherently self-adaptive to temporal fluctuation as well as spatial variation of the target temperature.
Additionally, by manipulating the configuration and composition of tungsten-doped vanadium dioxide on coatings applied to the PE tape, researchers can create an infrared decoy.
"How we grow the material changes the image people ultimately think they see.
This kind of technology could prove useful for military and intelligence agencies, as they seek to thwart increasingly sophisticated surveillance technologies that pose a threat to national security. It might also incubate future encryption technology, allowing information to be safely concealed from unauthorized access.
Kechao Tang et al. A Thermal Radiation Modulation Platform by Emissivity Engineering with Graded Metal–Insulator Transition, Advanced Materials (2020). DOI: 10.1002/adma.201907071
https://phys.org/news/2020-07-decoy-coatings-infrared-cameras.html?...
Jul 28, 2020
Dr. Krishna Kumari Challa
Testing Chernobyl fungi as a radiation shield for astronauts
How can astronauts survive high radiations during interplanetary travel?
A team of researchers has tested the viability of using a type of fungus found growing in some of the destroyed nuclear reactors at the former Chernobyl nuclear power plant site to shield astronauts from radiation.
Some fungi are able to flourish in a very highly radioactive place here on Earth—inside the destroyed reactors at the Chernobyl site in Ukraine. Testing of several types of the fungi has showed that they not only survive in the former reactors, but actually flourish. They have the ability to absorb radiation and to convert it into energy for their own use. To look into the possibility of using such types of fungus as a shield for humans, the researchers arranged with NASA to send a sample of one of the types of fungus found at Chernobyl—cladosporium sphaerospermum—to the International Space Station.
Once the fungus sample arrived at the ISS, astronauts monitored the petri dish set up by the researchers. One side of the petri dish was coated with the fungus; the other side had no fungus and served as a control. A detector was affixed to the back of the petri dish to measure radiation coming through. The detector was monitored for 30 days. The researchers found that the side of the petri dish that was covered with fungus reduced radiation levels coming through the dish by approximately 2% compared to the control side. That alone is inadequate as a safety shield, but the experiment serves as an indicator of what might be possible. On its own, the fungus is known to grow, which means a rocket carrying humans could carry just a small amount with them. Once on Mars, the fungus could be cultivated on a shield structure and allowed to thicken, offering perhaps one layer of protection very nearly free of charge.
Graham K. Shunk et al. A Self-Replicating Radiation-Shield for Human Deep-Space Exploration: Radiotrophic Fungi can Attenuate Ionizing Radiation aboard the International Space Station, bioRxiv (2020). DOI: 10.1101/2020.07.16.205534
https://phys.org/news/2020-07-chernobyl-fungi-shield-astronauts.htm...
Jul 28, 2020
Dr. Krishna Kumari Challa
Study: Mask-Wearing Moms with COVID-19 Can Safely Nurse Babies
None of the breastfed infants in the study tested positive for SARS-CoV-2 within the first two weeks of life.
https://www.the-scientist.com/news-opinion/study-mask-wearing-moms-...
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Microbial Signatures in Blood Are Associated with Various Cancers
A study suggests the potential for a noninvasive diagnostic that could detect tumors early and differentiate between disease types.
https://www.the-scientist.com/the-literature/microbial-signatures-i...
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https://www.sciencealert.com/here-s-what-our-plastic-waste-problem-...
Scientists Show How Bad Our Plastic Waste Problem Could Get by 2040
Jul 28, 2020
Dr. Krishna Kumari Challa
A scientist's mesmerizing animation shows how our entire solar system orbits an unseen center — and it's not the sun
A scientist's mesmerizing animation shows how our entire solar system orbits an unseen center — and it's not the sun: That center of mass is called the barycenter
Jul 28, 2020
Dr. Krishna Kumari Challa
Randomness theory could hold key to internet security
https://techxplore.com/news/2020-07-randomness-theory-key-internet....
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Study reveals how renegade protein interrupts brain cell function in Alzheimer's disease
https://medicalxpress.com/news/2020-07-reveals-renegade-protein-bra...
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https://medicalxpress.com/news/2020-07-airway-cells-regeneration-ag...
How airway cells work together in regeneration and aging
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https://phys.org/news/2020-07-billion-animals-affected-australia-bu...
Estimated 3 billion animals affected by Australia bushfires: study
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** Medieval medicine remedy could provide new treatment for modern day infections
https://phys.org/news/2020-07-medieval-medicine-remedy-treatment-mo...
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First Meta-Analysis Confirms Link Between Lithium in Drinking Water And Suicide Rates
https://www.sciencealert.com/first-meta-review-of-its-kind-confirms...
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AI Analysed Over 11,000 Couples' Relationships. This Is What It Found
https://www.sciencealert.com/ai-analysed-over-11-000-couples-relati...
Jul 29, 2020
Dr. Krishna Kumari Challa
New study reveals how day- and night-biting mosquitoes respond differently to colours of light and time of day
Researchers found that night- versus day-biting species of mosquitoes are behaviorally attracted and repelled by different colors of light at different times of day. Mosquitoes are among major disease vectors impacting humans and animals around the world and the findings have important implications for using light to control them.
The team studied mosquito species that bite in the daytime (Aedes aegypti, aka the Yellow Fever mosquito) and those that bite at night (Anopheles coluzzi, a member of the Anopheles gambiae family, the major vector for malaria). They found distinct responses to ultra violet and other colors of light between the two species. Researchers also found light preference is dependent on the mosquito's sex and species, the time of day and the colour of the light.
Insects are non-specifically attracted to ultraviolet light, hence the widespread use of ultraviolet light "bug zappers" for insect control. this research found that day-biting mosquitoes are attracted to a wide range of light spectra during the daytime, whereas night-biting mosquitoes are strongly photophobic to short-wavelength light during the daytime. Therefore, timing and light spectra are critical for species-specific light control of harmful mosquitoes.
The new work shows that day-biting mosquitoes, particularly females that require blood meals for their fertilized eggs, are attracted to light during the day regardless of spectra. In contrast, night-biting mosquitoes specifically avoid ultraviolet (UV) and blue light during the day. Previous work using fruit flies (which are related to mosquitoes) has determined the light sensors and circadian molecular mechanisms for light mediated attraction/avoidance behaviours. Accordingly, molecular disruption of the circadian clock severely interferes with light-evoked attraction and avoidance behaviours in mosquitoes. At present, light-based insect controls do not take into consideration the day versus night behavioural profiles that change with daily light and dark cycles.
Light is the primary regulator of circadian rhythms and evokes a wide range of time-of-day specific behaviours. By gaining an understanding of how insects respond to short wavelength light in a species-specific manner, we can develop new, environmentally friendly alternatives to controlling harmful insects more effectively and reduce the need for environmentally damaging toxic pesticides.
Lisa S. Baik et al, Circadian Regulation of Light-Evoked Attraction and Avoidance Behaviors in Daytime- versus Nighttime-Biting Mosquitoes, Current Biology (2020). DOI: 10.1016/j.cub.2020.06.010
https://phys.org/news/2020-07-reveals-day-night-biting-mosquitoes-d...
Jul 29, 2020
Dr. Krishna Kumari Challa
Discovery will allow more sophisticated work at nanoscale
The movement of fluids through small capillaries and channels is crucial for processes ranging from blood flow through the brain to power generation and electronic cooling systems, but that movement often stops when the channel is smaller than 10 nanometers.
Researchers have reported a new understanding of the process and why some fluids stagnate in these tiny channels, as well as a new way to stimulate the fluid flow by using a small increase in temperature or voltage to promote mass and ion transport.
The work explores the movement of fluids with lower surface tension, which allows the bonds between molecules to break apart when forced into narrow channels, stopping the process of fluid transport, known as capillary wicking.
This capillary force drives liquid flow in small channels and is the critical mechanism for mass transport in nature and technology—that is, in situations ranging from blood flow in the human brain to the movement of water and nutrients from soil to plant roots and leaves, as well as in industrial processes.
But differences in the surface tension of some fluids causes the wicking process—and therefore, the movement of the fluid—to stop when those channels are smaller than 10 nanometers. The researchers reported that it is possible to prompt continued flow by manipulating the surface tension through small stimuli, such as raising the temperature or using a small amount of voltage.
The temperature even slightly can activate movement by changing surface tension, which they dubbed "nanogates." Depending on the liquid, raising the temperature between 2 degrees Centigrade and 3 degrees C is enough to mobilize the fluid.The surface tension can be changed through different variables.
The simplest one is temperature. If you change temperature of the fluid, you can activate this fluid flow again." The process can be fine-tuned to move the fluid, or just specific ions within it, offering promise for more sophisticated work at nanoscale.
"The surface tension nanogates promise platforms to govern nanoscale functionality of a wide spectrum of systems, and applications can be foreseen in drug delivery, energy conversion, power generation, seawater desalination, and ionic separation.
Masoumeh Nazari et al. Surface Tension Nanogates for Controlled Ion Transport, ACS Applied Nano Materials (2020). DOI: 10.1021/acsanm.0c01304
https://phys.org/news/2020-07-discovery-sophisticated-nanoscale.htm...
Jul 29, 2020