By Losing Genes, Life Often Evolved More Complexity
Recent major surveys show that reductions in genomic complexity — including the loss of key genes — have successfully shaped the evolution of life throughout history.
Researchers find a cause and possible treatment for Fragile X syndrome
Scientists have discovered an underlying mechanism for Fragile X syndrome — a leading cause of autism and the primary genetic driver of intellectual disability — as well as a drug that reversed the underlying abnormality and autism-like behaviors in mice. Their research appears in the Sept. 3 edition of the journal Cell.
Fragile X, a genetic disorder linked to the X chromosome, leads to learning disabilities, cognitive impairment, and many features of autism, including social difficulties. Approximately one in 7,000 males and one in 11,000 females have the syndrome. Fragile X typically becomes evident in children by age 2.
The new Yale study deepens basic understanding of the syndrome and demonstrates early promise for a previously unexplored avenue for treatment.
In the study researchers focused on a protein called adenosine triphosphate synthase, which is present in nearly all cells in the body. It uses energy from food to generate adenosine triphosphate (ATP), a molecule that is a major energy source for cells.
In Fragile X syndrome, cells’ ATP-making function is abnormal,the team found. Specifically, the cells’ mitochondria — which process fuel to make ATP — have a leaky inner membrane.
This leaky membrane is making the process of ATP production inefficient. In Fragile X neurons, the synapses fail to mature during development. The synapses remain in an immature state and this seems to be related to their immature metabolism. When a leak in the cell’s mitochondria short-circuits efficient functioning of the synapse, memory, learning and typical brain development are all compromised.
Patients withCOVID-19shouldn’t have to die alone. Here’s how a loved one could be there at the end
We can strike a balance between minimising transmission risk and practising compassion to allow loved ones to visit patients with COVID-19 in ICU at the end of their lives.
Stone forests—pointed rock formations resembling trees that populate regions of China, Madagascar, and many other locations worldwide—are as majestic as they are mysterious, created by uncertain forces that give them their shape.
A team of scientists has now shed new light on how these natural structures are created. Through a series of simulations and experiments, they show how flowing water carves ultra-sharp spikes in landforms. In their study, the scientists simulated the formation of these pinnacles over time through a mathematical model and computer simulations that took into account how dissolving produces flows and how these flows also affect dissolving and thus reshaping of a formation.
To confirm the validity of their simulations, the researchers conducted a series of experiments in NYU's Applied Mathematics Lab. Here, the scientists replicated the formation of these natural structures by creating sugar-based pinnacles, mimicking soluble rocks that compose karst and similar topographies, and submerging them in tanks of water. Interestingly, no flows had to be imposed, since the dissolving process itself created the flow patterns needed to carve spikes.
The experimental resultsreflected those of the simulations, thereby supporting the accuracy of the researchers' model (see "Video2ExperimentSimulation" in the below drive). The authors speculate that these same events happen—albeit far more slowly—when minerals are submerged under water, which later recedes to reveal stone pinnacles and stone forests.
Animal skin is an excellent material, but the tanning process of leather causes significant chromium emissions that are damaging to the environment and human health. Synthetic leathers also burden the environment and fail to match the quality and durability of animal leather. Therefore, new bio-based replacement materials are sought for leather. Researchers now are using fungal mycelium to produce skinlike material that would be suited for industrial production.
For centuries, fungi and polypores have been used for making skinlike fabrics and accessories in Europe. Designers and researchers are now reviving this tradition to find sustainable alternatives to replace leather.
Scientists have been studying fungi and other microbes and their use in industrial biotechnology for quite a while. In laboratory conditions, fungal mycelium can be used to rapidly produce skinlike material with quite similar feel and tensile strength as animal skin.
Some items made of fungus-based leather are already being produced for commercial markets.
The production process of fungus-based leather represents creativity at its best: organic waste can be used as raw material for synthetic leather. Fungal mycelium can produce skinlike material out of, for example, food waste.
MRI scans show brain reorganization during long space flights, but no neurodegeneration
An international team of researchers has found that long space flights can lead to some minor brain reorganization but no neurodegeneration.
The group describes their study of the brains of cosmonauts returning from long-term missions aboard the International Space Station, and what they found.
The researchers found that the brain reorients itself during long space missions, essentially floating into different parts of the skull. This resulted in slight reorganization of the brain itself in response to the reorientation. The cosmonauts brains also responded in other ways to the unusual living environment—they acquired new motor skills and had better balance and coordination. The researchers also found that the reorientation did not result in neurodegeneration and that normal orientation was nearly restored seven months after the cosmonauts returned to Earth. They also confirmed fluid build-up behind the eyes as the reason for the loss of visual acuity during long space flights.
Steven Jillings et al. Macro- and microstructural changes in cosmonauts' brains after long-duration spaceflight, Science Advances (2020). DOI: 10.1126/sciadv.aaz9488
Genetic study of proteins is a breakthrough in drug development for complex diseases
An innovative genetic study of blood protein levels by researchers has demonstrated how genetic data can be used to support drug target prioritization by identifying the causal effects of proteins on diseases.
Methane-eating bacteria can degrade ammonium in addition to methane, as discovered by microbiologists . Methane-eaters are important for the reduction of greenhouses gas emissions from volcanoes and other areas, but have not previously been linked with nitrogen emission.
Wouter Versantvoort et al., Multiheme hydroxylamine oxidoreductases produce NO during ammonia oxidation in methanotrophs. PNAS (2020). (to be published)
Herring gulls notice where approaching humans are looking, and flee sooner when they're being watched, a new study shows.
Researchers approached gulls while either looking at the ground or directly at the birds.
Gulls were slower to move away when not being watched—allowing a human to get two metres closer on average.
Newly fledged gulls were just as likely to react to human gaze direction as older birds, suggesting they are born with this tendency or quickly learn it.
Madeleine Goumas et al. Herring gull aversion to gaze in urban and rural human settlements, Animal Behaviour (2020). DOI: 10.1016/j.anbehav.2020.08.008
Buffer could limit environmental spread of antibiotic resistance
Many livestock receive antibiotics that protect against bacterial diseases. But over time, antibiotics also trigger the evolution of bacteria that can resist them. Those antibiotic-resistant bacteria, in turn, can pass along genes responsible for that resistance to other bacterial species, ultimately reducing the effectiveness of the drugs
When manure from livestock administered with antibiotics is applied as fertilizer, antibiotic resistance genes can enter soil and, following precipitation, run off into rivers and other bodies of water, furthering their spread.
A research team ran experiments to evaluate the minimum distance between a manure slurry-covered field and surface waterthat would prevent the runoff of antibiotics and antibiotic resistance genes. The team found that levels of all three antibiotics it measured, along with seven of the 10 resistance genes, substantially decreased as that distance increased.
The researchers concluded that maintaining between 112 and 220 feet of distance would limit most runoff pollution across a no-till field rich in the clay soils .
Because that recommended distance is specific to the experimental site, the team recommended running similar experiments with varying field conditions, soil types, slopes and rainfall amounts to calibrate suitable distances elsewhere.
Maria C. Hall et al. Influence of Setback Distance on Antibiotics and Antibiotic Resistance Genes in Runoff and Soil Following the Land Application of Swine Manure Slurry, Environmental Science & Technology (2020). DOI: 10.1021/acs.est.9b04834
Solar cell floats on a soap bubble Materials scientists have made printed solar cells that are so thin, light and flexible that they can rest on the surface of a soap bubble.
Are Tardigrades The Most Indestructible Animals on Earth? There's a Close Contender
Tardigrades may be the most indestructible animal, but they are not resistant to any type of harm and many experts say Nematodes are a close challenger to this title.
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Scientists Have Found a Way to Make Foldable Keyboards Out of Any Paper
A new way to make bacteria more sensitive to antibiotics
Researchershave discovered a new way to reverse antibiotic resistance in some bacteria using hydrogen sulfide (H2S).
This is a very exciting discovery because for the first time it 's shown that H2S can, in fact, improve sensitivity to antibiotics, and even reverse antibiotic resistance in bacteria that do not naturally produce the agent.
While the study focused on the effects of exogenous H2S on A. baumannii, the scientists believe the results will be mimicked in all bacteria that do not naturally produce H2S.
Running is a fundamental mode of human movement that most of us perform effortlessly without conscious thought. Some may run regularly for exercise, or even undergo serious, professional training for completing marathons. This apparent ease of running belies the enormous biomechanical complexity of running, the coordinated control of which is accomplished by an intricate neuronal network in the brain and spinal cord.
Researchers have recently discovered that the human nervous system is equipped with a mechanism that can flexibly adjust the motor commands for different running forms depending on the state of the body and the person’s prior running experience. This finding, which has just been published in Nature Communications, may allow researchers to design training strategies for promoting running forms that are more energetically efficient.
A global analysis reveals for the first time that across almost all tree species, fast growing trees have shorter lifespans. This international study further calls into question predictions that greater tree growth means greater carbon storage in forests in the long term.
Study highlights the role of astrocytes in the formation of remote memories
Memories from a distant past, also known as remote memories, can guide the present and future behavior of humans and other living organisms on Earth. In psychology and neuroscience, the term "remote memories" refers to all memories related to events that took place from a few weeks to decades in the past.
Earlier studies have explored the neural underpinnings of remote memories or tried to identify brain regions that could be involved in how they are formed and maintained over time. So far, most findings have suggested that the interaction between the hippocampus and frontal cortical brain regions plays a key role in the consolidation of these memories.
Past observations suggest that the interaction between these brain regions changes as time goes by and as memories go from being recent (i.e., a few years old) to remote. The exact time when thesebrain regionsbecome involved in the formation of amemoryand for how long they remain important to its endurance, however, is still poorly understood.
Astrocytes are star-shaped cells that are known to have several functions, including the regulation of the metabolism, detoxification, tissue repair and providing nutrients to neurons. Recent studies have found that these cells can also change synaptic activity in the brain, thus impacting neuronal circuits at multiple levels.
A number of new observations that shed light on the unique contribution of these cells in enabling the formation of remote memories in mice, and potentially also humans have been made now. They provide further evidence that astrocytes can shape neuronal networks in intricate ways and affect many cognitive functions, including the acquisition of remote memories.
Adi Kol et al. Astrocytes contribute to remote memory formation by modulating hippocampal–cortical communication during learning, Nature Neuroscience (2020). DOI: 10.1038/s41593-020-0679-6
Metastases are formed by cancer cells that break away from the primary tumor. A research group at the University of Basel has now identified lack of oxygen as the trigger for this process. The results reveal an important relationship between the oxygen supply to tumors and the formation of metastases. This research may open up new treatment strategies for cancer.
The chances of recovery significantly worsen when a tumor metastasizes. Previous research has shown that metastases are formed by clusters of cancer cells that separate from the primary tumor and migrate to new tissue through the bloodstream. However, thus far little has been known about why these clusters of circulating tumor cells (CTCs) leave the tumor in the first place.
It has been shown now that a lack of oxygen is responsible for the separation of CTC clusters from the tumor. This is an important starting point for the development of new cancer treatments.
It turned out that different areas of a tumor are supplied with different levels of oxygen: cancer cells with a lack of oxygen were found wherever the tumor had comparatively fewer blood vessels—in the core of the tumor as well as in clearly defined peripheral areas. Next, the research team investigated the CTC clusters that had separated from these tumors and found that they similarly suffered from a lack of oxygen. This led to the conclusion that cells leave the tumor if they do not receive enough oxygen. "It's as though too many people are crowded together in a small space. A few will go outside to find some fresh air.
Further experiments showed that these CTC clusters with a lack of oxygen are particularly dangerous: in comparison to clusters with normal oxygen content, they formed metastases faster and shortened the mice's survival time. "If a tumor does not have enough oxygen, these CTC clusters, which have a particularly high potential to develop metastases, will break away.
This insight led the researchers to take a closer look at the effect of what is called proangiogenic treatment: they stimulated the formation of blood vessels, thus boosting the supply of oxygen to the tumor cells. As expected, the number of separating CTC clusters dropped, the mice formed fewer metastases, and they lived longer—but at the same time, the primary tumor increased in size significantly.
No signs of alien technology in 10 million star systems
A radio telescope in outback Western Australia has completed the deepest and broadest search at low frequencies for alien technologies, scanning a patch of sky known to include at least 10 million stars.
Astronomers used the Murchison Widefield Array (MWA)telescope to explore hundreds of times more broadly than any previous search for extraterrestrial life.
The study, published recently observed the sky around the Vela constellation. But in this part of the Universe at least, it appears other civilisations are elusive, if they exist. The telescope was searching for powerful radio emissions at frequencies similar to FM radio frequencies, that could indicate the presence of an intelligent source.
These possible emissions are known as 'technosignatures'. With this dataset, the study found no technosignatures—no sign of intelligent life.
''A SETI Survey of the Vela Region using the Murchison Widefield Array: Orders of Magnitude Expansion in Search Space', published in Publications of the Astronomical Society of Australia (PASA) on September 8th, 2020. arxiv.org/pdf/2009.03267.pdf
Future wireless networks of the 6th generation (6G) will consist of a multitude of small radio cells that need to be connected by broadband communication links. In this context, wireless transmission at THz frequencies represents a particularly attractive and flexible solution. Researchers have now developed a novel concept for low-cost terahertz receivers.
Engineered 'nanobodies' block SARS-CoV-2 from infecting human cells
Researchers have designed a molecule that sticks tightly to the coronavirus spike protein, preventing the virus from infecting cells. The molecule might someday be used in an aerosolized drug to treat or prevent COVID-19. It's modeled after the simple, compact antibodies found in some animals such as llamas, alpacas, and camels.
Immune cells produce antibodies in response to infection, but it takes time for that response to develop. Lab-made antibodies could knock a virus out before it gains a foothold.
Michael Schoof et al. An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by locking Spike into an inactive conformation, (2020). DOI: 10.1101/2020.08.08.238469
Dense metallic hydrogen—a phase of hydrogen which behaves like an electrical conductor—makes up the interior of giant planets. By combining artificial intelligence and quantum mechanics, researchers now have found how hydrogen becomes a metal under the extreme pressure conditions of these planets.
Researchers used machine learning to mimic the interactions between hydrogen atoms in order to overcome the size and timescale limitations of even the most powerful supercomputers. They found that instead of happening as a sudden, or first-order, transition, the hydrogen changes in a smooth and gradual way.
Hydrogen, consisting of one proton and one electron, is both the simplest and the most abundant element in the Universe. It is the dominant component of the interior of the giant planets in oursolar system—Jupiter, Saturn, Uranus, and Neptune—as well as exoplanets orbiting other stars.
At the surfaces of giant planets, hydrogen remains a molecular gas. Moving deeper into the interiors of giant planets however, the pressure exceeds millions of standard atmospheres. Under this extreme compression, hydrogen undergoes a phase transition: the covalent bonds inside hydrogen molecules break, and the gas becomes a metal that conducts electricity.
Human genes spring into action through instructions delivered by the precise order of our DNA, directed by the four different types of individual links, or "bases," coded A, C, G and T.
Nearly 25% of our genes are widely known to be transcribed by sequences that resemble TATAAA, which is called the "TATA box." How the other three-quarters are turned on, or promoted, has remained a mystery due to the enormous number of DNA base sequence possibilities, which has kept the activation information shrouded.
Now, with the help of artificial intelligence, researchers have identified a DNA activation code that's used at least as frequently as the TATA box in humans. Their discovery, which they termed the downstream core promoter region (DPR), could eventually be used to control gene activation in biotechnology and biomedical applications.
The researchers made a pool of 500,000 random versions of DNA sequences and evaluated the DPR activity of each. From there, 200,000 versions were used to create a machine learning model that could accurately predict DPR activity in human DNA.
These results clearly revealed the existence of the DPR motif in human genes. Moreover, the frequency of occurrence of the DPR appears to be comparable to that of the TATA box. In addition, they observed an intriguing duality between the DPR and TATA. Genes that are activated with TATA box sequences lack DPR sequences, and vice versa.
Sound waves replace human hands in petri dish experiments
Mechanical engineers have demonstrated a set of prototypes for manipulating particles and cells in a Petri dish using sound waves. The devices, known in the scientific community as "acoustic tweezers," are the first foray into making these types of tools, which have thus far been relegated to laboratories with specific equipment and expertise, available for use in a wide array of settings.
Acoustic tweezers are a powerful, versatile set of tools that use sound waves to manipulate bioparticles ranging from nanometer-sized extracellular vesicles to millimeter-sized multicellular organisms. Over the past several decades, the capabilities of acoustic tweezers have expanded from simplistic particle trapping to the precise rotation and translation of cells and organisms in three dimensions.
"Generating multifunctional acoustic tweezers in Petri dishes for contactless, precise manipulation of bioparticles" Science Advances (2020). DOI: 10.1126/sciadv.abb0494
From false dichotomies — save lives or save the economy? — to the ‘prevention paradox’ that breeds complacency when public-health measures work, many of us suffer from conceptual errors when it comes to coronavirus.
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Space Could Be Littered With Eerie Transparent Stars Made Entirely of Bosons
The Most Common Pain Relief Drug in The World Induces Risky Behaviour, Study Suggests
Acetaminophen, also known as paracetamol and sold widely under the brand names Tylenol and Panadol, also increases risk-taking, according to a new study that measured changes in people's behaviour when under the influence of the common over-the-counter medication.
Researchers reveal a much richer picture of the past with new DNA recovery technique
Researchers at McMaster University have developed a new technique to tease ancient DNA from soil, pulling the genomes of hundreds of animals and thousands of plants—many of them long extinct—from less than a gram of sediment.
The DNA extraction method, outlined in the journalQuarternary Research, allows scientists to reconstruct the most advanced picture ever of environments that existed thousands of years ago.
The researchers analyzed permafrost samples from four sites in the Yukon, each representing different points in the Pleistocene-Halocene transition, which occurred approximately 11,000 years ago.
This transition featured the extinction of a large number of animal species such as mammoths, mastodons and ground sloths, and the new process has yielded some surprising new information about the way events unfolded, say the researchers.
Tyler J. Murchie et al, Optimizing extraction and targeted capture of ancient environmental DNA for reconstructing past environments using the PalaeoChip Arctic-1.0 bait-set, Quaternary Research (2020). DOI: 10.1017/qua.2020.59
At least 28 extinctions prevented by conservation action in recent decades
Conservation action has prevented the global extinction of at least 28 bird and mammal species since 1993, a study has shown.
The species include Puerto Rican Amazon Amazona vittata, Przewalski's Horse Equus ferus, Alagoas Antwren Myrmotherula snowi, Iberian Lynx Lynx pardinus, and Black Stilt Himantopus novaezelandiae, among others.
an international team of scientists have estimated the number of bird and mammalspecies that would have disappeared forever without the efforts of conservationists in recent decades.
The researchers found that 21-32 bird and 7-16 mammal species extinctions have been prevented since 1993, with the ranges reflecting the uncertainty inherent in estimating what might have happened under hypothetical circumstances.
Bolam, F.C, Mair, L., Angelico, M., Brooks, T.M, Burgman, M., McGowan, P. J. K & Hermes, C. et al. (2020). How many bird and mammal extinctions has recent conservation action prevented? Conservation Letters (2020). DOI: 10.1111/conl.12762
Study finds humans are behind costly, increasing risk of wildfire to millions of homes
People are starting almost all the wildfires that threaten U.S. homes, according to an innovative new analysis combining housing and wildfire data. Through activities like debris burning, equipment use and arson, humans were responsible for igniting 97% of home-threatening wildfires, a University of Colorado Boulder-led team reported this week in the journal Fire.
Nathan Mietkiewicz et al, In the Line of Fire: Consequences of Human-Ignited Wildfires to Homes in the U.S. (1992–2015), Fire (2020). DOI: 10.3390/fire3030050
The Earth's magnetic field traps high-energy particles. When the first satellites were launched into space, scientists led by James Van Allen unexpectedly discovered the high-energy particle radiation regions, which were later named after its discoverer: the Van Allen Radiation Belts. Visualized, these look like two donut-shaped regions encompassing the planet.
Now, a new study led by researchers from GFZ German Research Center for Geosciences shows that electrons in the radiation belts can be accelerated to very high speeds locally. The study shows that magnetosphere works as a very efficient particle accelerator, speeding up electrons to so-called ultra-relativistic energies.
To better understand the origin of the Van Allen Belts, in 2012, NASA launched the Van Allen Probes twin spacecraft to traverse this mostharsh environmentand conduct detailed measurements in this hazardous region. The measurements included a full range of particles moving at different speeds and in different directions, and plasma waves. Plasma waves are similar to the waves that we see on the water surface, but are invisible to the naked eye. They can be compared to ripples in the electric and magnetic field.
Recent observations revealed that theenergyof electrons in the belts can go up to so called ultra-relativistic energies. These electrons, with temperatures above 100 billion degrees Fahrenheit, move so quickly that their energy of motion is much higher than their energy of rest given by Einstein's famous formula E=mc2. They are so fast that the time significantly slows down for these particles.
Scientists were surprised to find these ultra-relativistic electrons and assumed that such high energies can be only reached by a combination of two processes: the inward transport of particles from the outer regions of the magnetosphere, which accelerates them, and a local acceleration of particles by plasma waves.
However, the new study shows that electrons reach such incredible energies locally, in the heart of the belts, by taking all this energy from plasma waves. This process turns out to be extremely efficient. The unexpected discovery of how acceleration of particles to ultra-relativistic energies operates in the near-Earth space may help scientists understand the fundamental processes of acceleration on the sun, near outer planets, and even in the distant corners of the universe, wherespace probescannot reach.
Hayley Allison, Yuri Shprits: "Local heating of radiation belt electrons to ultra-relativistic energies" Nature Communications, DOI: 10.1038/s41467-020-18053-z
When stars and planets are formed, they do so from the same cloud of gas, so their bulk compositions are similar. A star with a lower carbon to oxygen ratio will have planets like Earth, comprised of silicates and oxides with a very small diamond content (Earth's diamond content is about 0.001%).
But exoplanets around stars with a higher carbon to oxygen ratio than our sun are more likely to be carbon-rich.Researchers hypothesized that these carbon-rich exoplanets could convert to diamond and silicate, if water (which is abundant in the universe) were present, creating a diamond-rich composition.
H. Allen-Sutter et al, Oxidation of the Interiors of Carbide Exoplanets, The Planetary Science Journal (2020). DOI: 10.3847/PSJ/abaa3e
Infection higher in hospital cleaners than ICU staff: report
Intensive care medics were significantly less likely to have been infected with COVID-19 than cleaners and other healthcare workers in departments deemed lower risk, according to a study of several British hospitals at the peak of the pandemic.
The research also found that people of black, Asian and minority ethnicity were nearly twice as likely to have been infected as white colleagues.
It follows several studies suggesting race, income and allocation of personal protective equipment (PPE) create biases in the burden of infections.
Researchers said the results could be because those working in intensive therapy units (ITU) were prioritised for the highest level of masks and other equipment.
SARS-CoV-2 seroprevalence and asymptomatic viral carriage in healthcare workers: a cross-sectional study, Thorax (2020). DOI: 10.1136/thoraxjnl-2020-215414
Researchers quantify worldwide loss of phosphorus due to soil erosion for the first time
Phosphorus is essential for agriculture, yet this important plant nutrient is increasingly being lost from soils around the world. The primary cause is soil erosion, reports an international research team.
The world's food production depends directly on phosphorus. However, this plant nutrient is not unlimited, originating from finite geological reserves.
Erosion flushes mineral-bound phosphorus out of agricultural soils into wetlands and water bodies, where the excess of nutrients (called eutrophication) harms the aquatic plant and animal communities. The researchers were able to validate their calculations using globally published measurement data on phosphorus content in rivers: The elevated phosphorus content in waters mirrors the calculated loss of phosphorus in the soil in the respective region.
Mineral fertilizers can replace the lost phosphorus in the fields, but not all countries are equally able to use them.
Christine Alewell et al. Global phosphorus shortage will be aggravated by soil erosion, Nature Communications (2020). DOI: 10.1038/s41467-020-18326-7
Elephant tusks do not grow back, but rhino horns do.
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scientists have developed a non-invasive technique for unraveling the complex dynamics generated by spinal cord circuits to unprecedented detail, a first in functional magnetic resonance imaging that may one day help diagnose spinal cord dysfunction or injury.
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Children born to mothers who had diabetes during pregnancy may age faster biologically and be at an increased risk for obesity and high blood pressure
Computational modelling explains why blues and greens are brightest colous in nature
Researchers have shown why intense, pure red colors in nature are mainly produced by pigments, instead of the structural color that produces bright blue and green hues.
The researchers, from the University of Cambridge, used anumerical experimentto determine the limits of matt structural color—a phenomenon which is responsible for some of the most intense colors in nature—and found that it extends only as far as blue and green in the visible spectrum. The results, published inPNAS, could be useful in the development of non-toxic paints or coatings with intense color that never fades.
Structural color, which is seen in some bird feathers, butterfly wings or insects, is not caused by pigments or dyes, but internalstructurealone. The appearance of the color, whether matt or iridescent, will depending on how the structures are arranged at the nanoscale.
Ordered, or crystalline, structures result in iridescent colors, which change when viewed from different angles. Disordered, or correlated, structures result in angle-independent matt colors, which look the same from any viewing angle. Since structural color does not fade, these angle-independent matt colors would be highly useful for applications such as paints or coatings, where metallic effects are not wanted.
In addition to their intensity and resistance to fading, a matt paint which uses structural color would also be far more environmentally-friendly, as toxic dyes and pigments would not be needed.
Gianni Jacucci et al, The limitations of extending nature's color palette in correlated, disordered systems, Proceedings of the National Academy of Sciences (2020). DOI: 10.1073/pnas.2010486117
Surgeons could dramatically reduce the risk of infection after an operation by simply changing the antiseptic they use.
New analysis by the University of Leeds and the University of Bern of more than 14,000 operations has found that using alcoholic chlorhexidine gluconate (CHG) halves the risk of infection in certain types of surgery when compared to the more commonly used povidone-iodine (PVI).
Infection after surgery could result in a range of issues including readmission to hospital and possibly further surgery.
The WWF’s Living Planet Report 2020 presents a comprehensive overview of the state of our natural world as captured by the Living Planet Index (LPI). Almost 21,000 populations of over 4,000 vertebrate species were tracked between 1970 and 2016, with contributions from over 125 experts from around the world.
The Living Planet Report 2020 underlines how humanity’s increasing destruction of nature is having catastrophic impacts not only on wildlife populations, but on human health and all aspects of our lives.
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There’s no evidence that blue-light blocking glasses help with sleep
Math Shows How Famed Indus Valley Civilization May Have Been Toppled by Climate Change
There are competing hypotheses around the decline of the Indus Valley Civilization in South Asia some 3,000 years ago, but a new mathematical proof has identified that climate change could have been responsible.
Mathematical scientist Nishant Malik from the Rochester Institute of Technology crunched the numbers and found new evidence to back up the idea that shifting monsoon seasons and increasing drought might have helped bring about the collapse of the Bronze Age empire.
By analysing the presence of a particular isotope in stalagmites in a North Indian cave – which should reveal the amount of water that fell as rain over time – scientists havepreviously been ableto estimate monsoon rainfall in the region over the past 5,700 years.
In the new research, Malik was able to identify patterns in this data showing a major shift in monsoon patterns as the civilization began to rise, and then a reverse shift that matched its decline.
Uncovering transitions in paleoclimate time series and the climate driven demise of an ancient civilization
A 13-million-year-old fossil unearthed in northern India comes from a newly discovered ape, the earliest known ancestor of the modern-day gibbon. The discovery fills a major void in the ape fossil record and provides important new evidence about when the ancestors of today's gibbon migrated to Asia from Africa. This discovery fills major gaps in the hominoid fossil record.
The fossil, a complete lower molar, belongs to a previously unknown genus and species (Kapi ramnagarensis) and represents the first new fossil ape species discovered at the famous fossil site of Ramnagar, India, in nearly a century.
New Middle Miocene Ape (Primates: Hylobatidae) from Ramnagar, India Fills Major Gaps in the Hominoid Fossil Record, Proceedings of the Royal Society B (2020). rspb.royalsocietypublishing.or … .1098/rspb.2020.1655
Gene-edited livestock 'surrogate sires' successfully made fertile
For the first time, scientists have created pigs, goats and cattle that can serve as viable "surrogate sires," male animals that produce sperm carrying only the genetic traits of donor animals.
could speed the spread of desirable characteristics in livestock and improve food production for a growing global population. It also would enable breeders in remote regions better access to genetic material of elite animals from other parts of the world and allow more precision breeding in animals such as goats where using artificial insemination is difficult.
Michela Ciccarelli el al., "Donor-derived spermatogenesis following stem cell transplantation in sterile NANOS2 knockout males," PNAS (2020). www.pnas.org/cgi/doi/10.1073/pnas.2010102117
Hints of life on Venus: Scientists detect phosphine molecules in high cloud decks
An international team of astronomers yesterday (14th sept., 2020) announced the discovery of a rare molecule—phosphine—in the clouds of Venus. On Earth, this gas is only made industrially, or by microbes that thrive in oxygen-free environments.
Astronomers have speculated for decades that high clouds on Venus could offer a home for microbes—floating free of the scorching surface, but still needing to tolerate very high acidity. The detection of phosphine molecules, which consist of hydrogen and phosphorus, could point to this extra-terrestrial 'aerial' life.
To create the observed quantity of phosphine on Venus, terrestrial organisms would only need to work at about 10% of their maximum productivity.
Greaves, J.S., Richards, A.M.S., Bains, W. et al. Phosphine gas in the cloud decks of Venus. Nat Astron (2020). doi.org/10.1038/s41550-020-1174-4
Animals' magnetic 'sixth' sense may come from bacteria, new paper suggests
Scientists hypothesis to the Q why some animals have a magnetic 'sixth' sense, such as sea turtles' ability to return to the beach where they were born: the magnetic sense comes from a symbiotic relationship with magnetotactic bacteria.
Magnetotactic bacteria are a special type of bacteria whose movement is influenced by magnetic fields, including the Earth's.
Animals that sense Earth'smagnetic fieldinclude sea turtles, birds, fish and lobsters. Sea turtles, for example, can use the ability for navigation to return to the beach where they were born.
Learning how organisms interact with magnetic fields can improve humans' understanding of how to use Earth's magnetic fields for their own navigation purposes. It can also inform ecological research into the effects of human modifications of the magnetic environment, such as constructing power lines, on biodiversity. Research into the interaction of animals with magnetic fields can also aid the development of therapies that use magnetism for drug delivery.
In the article, the researchers review the arguments for and against the hypothesis, present evidence published in support that has arisen in the past few years, as well as offer new supportive evidence of their own.
Their new evidence comes from microbes ( Metagenomic Rapid Annotations using Subsystems Technology database), the magnetotactic bacteria that had been found in animal samples. Scientists found for the first time, that magnetotactic bacteria are associated with many animals, including a penguin species, loggerhead sea turtles, bats and Atlantic right whales.
the hypothesis that animals use magnetic bacteria in a symbiotic way to gain a magnetic sense warrants further exploration but still needs more evidence before anything conclusive can be stated.
Eviatar Natan et al, Symbiotic magnetic sensing: raising evidence and beyond, Philosophical Transactions of the Royal Society B: Biological Sciences (2020). DOI: 10.1098/rstb.2019.0595
Bioactive nano-capsules to hijack cell behaviour to treat diseases
Many diseases are caused by defects in signaling pathways of body cells. In the future, bioactive nanocapsules could become a valuable tool for medicine to control these pathways. Researchers have taken an important step in this direction: They succeed in having several different nanocapsules work in tandem to amplify a natural signaling cascade and influence cell behaviour.
Andrea Belluati et al, Bioactive Catalytic Nanocompartments Integrated into Cell Physiology and Their Amplification of a Native Signaling Cascade, ACS Nano (2020). DOI: 10.1021/acsnano.0c05574
Boron nitride nanofilms might replace antibiotics for protection against bacterial and fungal infections
Material scientists have presented antibacterial nano-coatings based on boron nitride, which are highly effective against microbial pathogens (up to 99.99%). They can become a safe alternative to the usual antibiotics in implantology since they do not have typical negative side effects.
Due to the significant increase in the number of surgical procedures around the world, scientists are addressing the problem of microbial infections caused by implants. It is especially serious during orthopedic and dental operations. It is no secret that concomitant drug therapy for inflammation around implants often leads to side effects due to the characteristic properties of the antibiotics, as well as the required high doses.
A group of scientists from has proposed a non-standard solution to the problem by investigating the interaction of antibiotic-resistant gram-negative bacteria Escherichia coli (E.coli) and a nanofilm consisting of a structured boron nitride surface. It turned out that such a coating inactivates 100% of bacterial cells after 24 hours.
Kristina Y. Gudz et al. Pristine and Antibiotic-Loaded Nanosheets/Nanoneedles-Based Boron Nitride Films as a Promising Platform to Suppress Bacterial and Fungal Infections, ACS Applied Materials & Interfaces (2020). DOI: 10.1021/acsami.0c10169
Physicists 'trick' photons into behaving like electrons using a 'synthetic' magnetic field
Scientists have discovered an elegant way of manipulating light using a 'synthetic' Lorentz force—which in nature is responsible for many fascinating phenomena including the Aurora Borealis.
A team of theoretical physicists from the University of Exeter has pioneered a new technique to create tuneable artificial magnetic fields, which enable photons to mimic the dynamics of charged particles in real magnetic fields.
The team believe the new research, published in leading journalNature Photonics, could have important implications for future photonic devices as it provides a novel way of manipulating light below the diffraction limit.
Dr. Krishna Kumari Challa
By Losing Genes, Life Often Evolved More Complexity
Mathematicians Report New Discovery About the Dodecahedron
Sep 5, 2020
Dr. Krishna Kumari Challa
The amazing phenomenon of sonic booms
Sep 6, 2020
Dr. Krishna Kumari Challa
Researchers find a cause and possible treatment for Fragile X syndrome
Scientists have discovered an underlying mechanism for Fragile X syndrome — a leading cause of autism and the primary genetic driver of intellectual disability — as well as a drug that reversed the underlying abnormality and autism-like behaviors in mice. Their research appears in the Sept. 3 edition of the journal Cell.
Fragile X, a genetic disorder linked to the X chromosome, leads to learning disabilities, cognitive impairment, and many features of autism, including social difficulties. Approximately one in 7,000 males and one in 11,000 females have the syndrome. Fragile X typically becomes evident in children by age 2.
The new Yale study deepens basic understanding of the syndrome and demonstrates early promise for a previously unexplored avenue for treatment.
In the study researchers focused on a protein called adenosine triphosphate synthase, which is present in nearly all cells in the body. It uses energy from food to generate adenosine triphosphate (ATP), a molecule that is a major energy source for cells.
In Fragile X syndrome, cells’ ATP-making function is abnormal,the team found. Specifically, the cells’ mitochondria — which process fuel to make ATP — have a leaky inner membrane.
This leaky membrane is making the process of ATP production inefficient. In Fragile X neurons, the synapses fail to mature during development. The synapses remain in an immature state and this seems to be related to their immature metabolism.
When a leak in the cell’s mitochondria short-circuits efficient functioning of the synapse, memory, learning and typical brain development are all compromised.
Source: https://news.yale.edu/2020/09/03/yale-researchers-find-cause-and-po...
https://researchnews.cc/news/2359/Yale-researchers-find-a-cause-and...
Sep 7, 2020
Dr. Krishna Kumari Challa
Cosmonaut Brain Scans Show Space Does Weird Things to Motor Skills And Vision
https://www.sciencealert.com/cosmonaut-brain-study-shows-how-space-...
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Patients with COVID-19 shouldn’t have to die alone. Here’s how a loved one could be there at the end
We can strike a balance between minimising transmission risk and practising compassion to allow loved ones to visit patients with COVID-19 in ICU at the end of their lives.
https://theconversation.com/patients-with-covid-19-shouldnt-have-to...
Sep 7, 2020
Dr. Krishna Kumari Challa
How stone forests get their spikes
Stone forests—pointed rock formations resembling trees that populate regions of China, Madagascar, and many other locations worldwide—are as majestic as they are mysterious, created by uncertain forces that give them their shape.
A team of scientists has now shed new light on how these natural structures are created. Through a series of simulations and experiments, they show how flowing water carves ultra-sharp spikes in landforms. In their study, the scientists simulated the formation of these pinnacles over time through a mathematical model and computer simulations that took into account how dissolving produces flows and how these flows also affect dissolving and thus reshaping of a formation.
To confirm the validity of their simulations, the researchers conducted a series of experiments in NYU's Applied Mathematics Lab. Here, the scientists replicated the formation of these natural structures by creating sugar-based pinnacles, mimicking soluble rocks that compose karst and similar topographies, and submerging them in tanks of water. Interestingly, no flows had to be imposed, since the dissolving process itself created the flow patterns needed to carve spikes.
The experimental results reflected those of the simulations, thereby supporting the accuracy of the researchers' model (see "Video2ExperimentSimulation" in the below drive). The authors speculate that these same events happen—albeit far more slowly—when minerals are submerged under water, which later recedes to reveal stone pinnacles and stone forests.
Jinzi Mac Huang el al., "Ultra-sharp pinnacles sculpted by natural convective dissolution," PNAS (2020). www.pnas.org/cgi/doi/10.1073/pnas.2001524117
https://phys.org/news/2020-09-stone-forests-spikes.html?utm_source=...
Sep 8, 2020
Dr. Krishna Kumari Challa
Stone forest ( Image credit: Google images)
Sep 8, 2020
Dr. Krishna Kumari Challa
Children use both brain hemispheres to understand language, unlike adults
https://medicalxpress.com/news/2020-09-children-brain-hemispheres-l...
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Superconductors are super resilient to magnetic fields
https://phys.org/news/2020-09-superconductors-super-resilient-magne...
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Alternative leather from fungi
https://phys.org/news/2019-12-alternative-leather-fungi.html
Animal skin is an excellent material, but the tanning process of leather causes significant chromium emissions that are damaging to the environment and human health. Synthetic leathers also burden the environment and fail to match the quality and durability of animal leather. Therefore, new bio-based replacement materials are sought for leather. Researchers now are using fungal mycelium to produce skinlike material that would be suited for industrial production.
For centuries, fungi and polypores have been used for making skinlike fabrics and accessories in Europe. Designers and researchers are now reviving this tradition to find sustainable alternatives to replace leather.
Scientists have been studying fungi and other microbes and their use in industrial biotechnology for quite a while. In laboratory conditions, fungal mycelium can be used to rapidly produce skinlike material with quite similar feel and tensile strength as animal skin.
Some items made of fungus-based leather are already being produced for commercial markets.
The production process of fungus-based leather represents creativity at its best: organic waste can be used as raw material for synthetic leather. Fungal mycelium can produce skinlike material out of, for example, food waste.
https://phys.org/news/2019-12-alternative-leather-fungi.html
https://www.quora.com/q/sciencecommunication/Alternative-leather-fr...; - check %%
Sep 8, 2020
Dr. Krishna Kumari Challa
MRI scans show brain reorganization during long space flights, but no neurodegeneration
An international team of researchers has found that long space flights can lead to some minor brain reorganization but no neurodegeneration.
The group describes their study of the brains of cosmonauts returning from long-term missions aboard the International Space Station, and what they found.
The researchers found that the brain reorients itself during long space missions, essentially floating into different parts of the skull. This resulted in slight reorganization of the brain itself in response to the reorientation. The cosmonauts brains also responded in other ways to the unusual living environment—they acquired new motor skills and had better balance and coordination. The researchers also found that the reorientation did not result in neurodegeneration and that normal orientation was nearly restored seven months after the cosmonauts returned to Earth. They also confirmed fluid build-up behind the eyes as the reason for the loss of visual acuity during long space flights.
Steven Jillings et al. Macro- and microstructural changes in cosmonauts' brains after long-duration spaceflight, Science Advances (2020). DOI: 10.1126/sciadv.aaz9488
https://phys.org/news/2020-09-mri-scans-brain-space-flights.html?ut...
Sep 8, 2020
Dr. Krishna Kumari Challa
Genetic study of proteins is a breakthrough in drug development for complex diseases
An innovative genetic study of blood protein levels by researchers has demonstrated how genetic data can be used to support drug target prioritization by identifying the causal effects of proteins on diseases.
Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases, Nature Genetics (2020). DOI: 10.1038/s41588-020-0682-6 , www.nature.com/articles/s41588-020-0682-6
https://phys.org/news/2020-09-genetic-proteins-breakthrough-drug-co...
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**New insight into mammalian stem cell evolution
https://phys.org/news/2020-09-insight-mammalian-stem-cell-evolution...
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** Methane-eating bacteria like nitrogen, too
Methane-eating bacteria can degrade ammonium in addition to methane, as discovered by microbiologists . Methane-eaters are important for the reduction of greenhouses gas emissions from volcanoes and other areas, but have not previously been linked with nitrogen emission.
Wouter Versantvoort et al., Multiheme hydroxylamine oxidoreductases produce NO during ammonia oxidation in methanotrophs. PNAS (2020). (to be published)
https://phys.org/news/2020-09-methane-eating-bacteria-nitrogen.html...
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Gulls pay attention to human eyes
Herring gulls notice where approaching humans are looking, and flee sooner when they're being watched, a new study shows.
Researchers approached gulls while either looking at the ground or directly at the birds.
Gulls were slower to move away when not being watched—allowing a human to get two metres closer on average.
Newly fledged gulls were just as likely to react to human gaze direction as older birds, suggesting they are born with this tendency or quickly learn it.
Madeleine Goumas et al. Herring gull aversion to gaze in urban and rural human settlements, Animal Behaviour (2020). DOI: 10.1016/j.anbehav.2020.08.008
https://phys.org/news/2020-09-gulls-attention-human-eyes.html?utm_s...
Sep 8, 2020
Dr. Krishna Kumari Challa
Buffer could limit environmental spread of antibiotic resistance
Many livestock receive antibiotics that protect against bacterial diseases. But over time, antibiotics also trigger the evolution of bacteria that can resist them. Those antibiotic-resistant bacteria, in turn, can pass along genes responsible for that resistance to other bacterial species, ultimately reducing the effectiveness of the drugs
When manure from livestock administered with antibiotics is applied as fertilizer, antibiotic resistance genes can enter soil and, following precipitation, run off into rivers and other bodies of water, furthering their spread.
A research team ran experiments to evaluate the minimum distance between a manure slurry-covered field and surface water that would prevent the runoff of antibiotics and antibiotic resistance genes. The team found that levels of all three antibiotics it measured, along with seven of the 10 resistance genes, substantially decreased as that distance increased.
The researchers concluded that maintaining between 112 and 220 feet of distance would limit most runoff pollution across a no-till field rich in the clay soils .
Because that recommended distance is specific to the experimental site, the team recommended running similar experiments with varying field conditions, soil types, slopes and rainfall amounts to calibrate suitable distances elsewhere.
Maria C. Hall et al. Influence of Setback Distance on Antibiotics and Antibiotic Resistance Genes in Runoff and Soil Following the Land Application of Swine Manure Slurry, Environmental Science & Technology (2020). DOI: 10.1021/acs.est.9b04834
https://phys.org/news/2020-09-buffer-limit-environmental-antibiotic...
Sep 8, 2020
Dr. Krishna Kumari Challa
How drones change our point of view and our truths
https://theconversation.com/eyes-on-the-world-drones-change-our-poi...
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Solar cell floats on a soap bubble
Materials scientists have made printed solar cells that are so thin, light and flexible that they can rest on the surface of a soap bubble.
https://www.nature.com/immersive/d41586-020-02493-0/index.html?utm_...
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These 3 Recent Studies Radically Change What We Understand About Dogs
https://www.sciencealert.com/three-new-studies-radically-change-wha...
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Scientists Awaken Deep Sea Bacteria After 100 Million Years
The microbes had survived on trace amounts of oxygen and were able to feed and multiply once revived in the lab.
https://www.the-scientist.com/news-opinion/scientists-awaken-deep-s...
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Gut Microbiome Composition Linked to Human Behavior
A study uncovers connections between the bacteria in our guts and our social lives.
https://www.the-scientist.com/the-literature/gut-microbiome-composi...
Sep 8, 2020
Dr. Krishna Kumari Challa
https://www.sciencealert.com/are-tardigrades-the-most-indestructibl...
Are Tardigrades The Most Indestructible Animals on Earth? There's a Close Contender
Tardigrades may be the most indestructible animal, but they are not resistant to any type of harm and many experts say Nematodes are a close challenger to this title.
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Scientists Have Found a Way to Make Foldable Keyboards Out of Any Paper
Cadmium levels in waste pickers ‘four times higher’
Sep 8, 2020
Dr. Krishna Kumari Challa
Gut Microbiome Composition Linked to Human Behavior
A study uncovers connections between the bacteria in our guts and our social lives.
https://www.the-scientist.com/the-literature/gut-microbiome-composi...
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** People Are Making Face Masks With Period Blood. Is There Science To Back It?
https://www.idiva.com/beauty/tips/why-menstrual-blood-facials-are-a...
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What are corticosteroids and why are they effective at fighting severe COVID-19?
https://theconversation.com/what-are-corticosteroids-and-why-are-th...
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Plant living with only one leaf reveals fundamental genetics of pla...
https://researchnews.cc/news/2406/Plant-living-with-only-one-leaf-r...
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Climate explained: methane is short-lived in the atmosphere but leaves long-term damage
https://theconversation.com/climate-explained-methane-is-short-live...
Sep 8, 2020
Dr. Krishna Kumari Challa
New study discovers how the nervous system of human runners generat...
Running is a fundamental mode of human movement that most of us perform effortlessly without conscious thought. Some may run regularly for exercise, or even undergo serious, professional training for completing marathons. This apparent ease of running belies the enormous biomechanical complexity of running, the coordinated control of which is accomplished by an intricate neuronal network in the brain and spinal cord.
Researchers have recently discovered that the human nervous system is equipped with a mechanism that can flexibly adjust the motor commands for different running forms depending on the state of the body and the person’s prior running experience. This finding, which has just been published in Nature Communications, may allow researchers to design training strategies for promoting running forms that are more energetically efficient.
https://www.nature.com/articles/s41467-020-18210-4.
https://researchnews.cc/news/2405/New-study-discovers-how-the-nervo...
Sep 8, 2020
Dr. Krishna Kumari Challa
Real-time imaging shows how SARS-CoV-2 attacks human cells
https://phys.org/news/2020-09-real-time-imaging-sars-cov-human-cell...
https://www.quora.com/q/sciencecommunication/Real-time-imaging-show... - check %%
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Devitrification demystified: Scientists show how glass crystallizes in real-time
https://phys.org/news/2020-09-devitrification-demystified.html?utm_...
https://www.quora.com/q/sciencecommunication/Devitrification-demyst...; - check %%
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** Terahertz receiver for 6G wireless communications
https://phys.org/news/2020-09-terahertz-6g-wireless.html?utm_source...
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** Trees living fast die young
A global analysis reveals for the first time that across almost all tree species, fast growing trees have shorter lifespans. This international study further calls into question predictions that greater tree growth means greater carbon storage in forests in the long term.
https://phys.org/news/2020-09-trees-fast-die-young.html?utm_source=...
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The birth of a male sex chromosome in Atlantic herring
https://phys.org/news/2020-09-birth-male-sex-chromosome-atlantic.ht...
Sep 9, 2020
Dr. Krishna Kumari Challa
Study highlights the role of astrocytes in the formation of remote memories
Memories from a distant past, also known as remote memories, can guide the present and future behavior of humans and other living organisms on Earth. In psychology and neuroscience, the term "remote memories" refers to all memories related to events that took place from a few weeks to decades in the past.
Earlier studies have explored the neural underpinnings of remote memories or tried to identify brain regions that could be involved in how they are formed and maintained over time. So far, most findings have suggested that the interaction between the hippocampus and frontal cortical brain regions plays a key role in the consolidation of these memories.
Past observations suggest that the interaction between these brain regions changes as time goes by and as memories go from being recent (i.e., a few years old) to remote. The exact time when these brain regions become involved in the formation of a memory and for how long they remain important to its endurance, however, is still poorly understood.
Astrocytes are star-shaped cells that are known to have several functions, including the regulation of the metabolism, detoxification, tissue repair and providing nutrients to neurons. Recent studies have found that these cells can also change synaptic activity in the brain, thus impacting neuronal circuits at multiple levels.
A number of new observations that shed light on the unique contribution of these cells in enabling the formation of remote memories in mice, and potentially also humans have been made now. They provide further evidence that astrocytes can shape neuronal networks in intricate ways and affect many cognitive functions, including the acquisition of remote memories.
Adi Kol et al. Astrocytes contribute to remote memory formation by modulating hippocampal–cortical communication during learning, Nature Neuroscience (2020). DOI: 10.1038/s41593-020-0679-6
https://medicalxpress.com/news/2020-09-highlights-role-astrocytes-f...
Sep 9, 2020
Dr. Krishna Kumari Challa
A lack of oxygen in tumors promotes metastasis
Metastases are formed by cancer cells that break away from the primary tumor. A research group at the University of Basel has now identified lack of oxygen as the trigger for this process. The results reveal an important relationship between the oxygen supply to tumors and the formation of metastases. This research may open up new treatment strategies for cancer.
The chances of recovery significantly worsen when a tumor metastasizes. Previous research has shown that metastases are formed by clusters of cancer cells that separate from the primary tumor and migrate to new tissue through the bloodstream. However, thus far little has been known about why these clusters of circulating tumor cells (CTCs) leave the tumor in the first place.
It has been shown now that a lack of oxygen is responsible for the separation of CTC clusters from the tumor. This is an important starting point for the development of new cancer treatments.
It turned out that different areas of a tumor are supplied with different levels of oxygen: cancer cells with a lack of oxygen were found wherever the tumor had comparatively fewer blood vessels—in the core of the tumor as well as in clearly defined peripheral areas. Next, the research team investigated the CTC clusters that had separated from these tumors and found that they similarly suffered from a lack of oxygen. This led to the conclusion that cells leave the tumor if they do not receive enough oxygen. "It's as though too many people are crowded together in a small space. A few will go outside to find some fresh air.
Further experiments showed that these CTC clusters with a lack of oxygen are particularly dangerous: in comparison to clusters with normal oxygen content, they formed metastases faster and shortened the mice's survival time. "If a tumor does not have enough oxygen, these CTC clusters, which have a particularly high potential to develop metastases, will break away.
This insight led the researchers to take a closer look at the effect of what is called proangiogenic treatment: they stimulated the formation of blood vessels, thus boosting the supply of oxygen to the tumor cells. As expected, the number of separating CTC clusters dropped, the mice formed fewer metastases, and they lived longer—but at the same time, the primary tumor increased in size significantly.
Cell Reports (2020). DOI: 10.1016/j.celrep.2020.108105
https://medicalxpress.com/news/2020-09-lack-oxygen-tumors-metastasi...
Sep 9, 2020
Dr. Krishna Kumari Challa
No signs of alien technology in 10 million star systems
A radio telescope in outback Western Australia has completed the deepest and broadest search at low frequencies for alien technologies, scanning a patch of sky known to include at least 10 million stars.
Astronomers used the Murchison Widefield Array (MWA)telescope to explore hundreds of times more broadly than any previous search for extraterrestrial life.
The study, published recently observed the sky around the Vela constellation. But in this part of the Universe at least, it appears other civilisations are elusive, if they exist. The telescope was searching for powerful radio emissions at frequencies similar to FM radio frequencies, that could indicate the presence of an intelligent source.
These possible emissions are known as 'technosignatures'. With this dataset, the study found no technosignatures—no sign of intelligent life.
''A SETI Survey of the Vela Region using the Murchison Widefield Array: Orders of Magnitude Expansion in Search Space', published in Publications of the Astronomical Society of Australia (PASA) on September 8th, 2020. arxiv.org/pdf/2009.03267.pdf
https://phys.org/news/2020-09-australian-telescope-alien-technology...
Sep 9, 2020
Dr. Krishna Kumari Challa
High Blood Pressure And Diabetes Could Alter Brain Structure, Slowing Down Cognition
https://www.sciencealert.com/study-suggests-diabetes-and-high-blood...
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Terahertz receiver for 6G wireless communications
Future wireless networks of the 6th generation (6G) will consist of a multitude of small radio cells that need to be connected by broadband communication links. In this context, wireless transmission at THz frequencies represents a particularly attractive and flexible solution. Researchers have now developed a novel concept for low-cost terahertz receivers.
https://www.sciencedaily.com/releases/2020/09/200908122517.htm
Sep 9, 2020
Dr. Krishna Kumari Challa
Wringing out Water on the ISS - for Science!
Sep 9, 2020
Dr. Krishna Kumari Challa
Massive halo finally explains stream of gas swirling around the Milky Way
https://phys.org/news/2020-09-massive-halo-stream-gas-swirling.html...
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Physicists explain mysterious dark matter deficiency in galaxy pair
https://phys.org/news/2020-09-physicists-mysterious-dark-deficiency...
https://www.quora.com/q/sciencecommunication/Massive-halo-finally-e...; --check %%%%
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A gold nanoparticle nearly cloaked by a single molecule
https://phys.org/news/2020-09-gold-nanoparticle-cloaked-molecule.ht...
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New Hubble data suggests there is an ingredient missing from current dark matter theories
https://phys.org/news/2020-09-hubble-ingredient-current-dark-theori...
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Engineered 'nanobodies' block SARS-CoV-2 from infecting human cells
Researchers have designed a molecule that sticks tightly to the coronavirus spike protein, preventing the virus from infecting cells. The molecule might someday be used in an aerosolized drug to treat or prevent COVID-19. It's modeled after the simple, compact antibodies found in some animals such as llamas, alpacas, and camels.
Immune cells produce antibodies in response to infection, but it takes time for that response to develop. Lab-made antibodies could knock a virus out before it gains a foothold.
Michael Schoof et al. An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by locking Spike into an inactive conformation, (2020). DOI: 10.1101/2020.08.08.238469
https://phys.org/news/2020-09-nanobodies-block-sars-cov-infecting-h...
Sep 10, 2020
Dr. Krishna Kumari Challa
How hydrogen becomes a metal inside giant planets
Dense metallic hydrogen—a phase of hydrogen which behaves like an electrical conductor—makes up the interior of giant planets. By combining artificial intelligence and quantum mechanics, researchers now have found how hydrogen becomes a metal under the extreme pressure conditions of these planets.
Researchers used machine learning to mimic the interactions between hydrogen atoms in order to overcome the size and timescale limitations of even the most powerful supercomputers. They found that instead of happening as a sudden, or first-order, transition, the hydrogen changes in a smooth and gradual way.
Hydrogen, consisting of one proton and one electron, is both the simplest and the most abundant element in the Universe. It is the dominant component of the interior of the giant planets in our solar system—Jupiter, Saturn, Uranus, and Neptune—as well as exoplanets orbiting other stars.
At the surfaces of giant planets, hydrogen remains a molecular gas. Moving deeper into the interiors of giant planets however, the pressure exceeds millions of standard atmospheres. Under this extreme compression, hydrogen undergoes a phase transition: the covalent bonds inside hydrogen molecules break, and the gas becomes a metal that conducts electricity.
Evidence for supercritical behaviour of high-pressure liquid hydrogen, Nature (2020). DOI: 10.1038/s41586-020-2677-y , www.nature.com/articles/s41586-020-2677-y
https://phys.org/news/2020-09-ai-hydrogen-metal-giant-planets.html?...
Sep 10, 2020
Dr. Krishna Kumari Challa
Gene activation discovery
Human genes spring into action through instructions delivered by the precise order of our DNA, directed by the four different types of individual links, or "bases," coded A, C, G and T.
Nearly 25% of our genes are widely known to be transcribed by sequences that resemble TATAAA, which is called the "TATA box." How the other three-quarters are turned on, or promoted, has remained a mystery due to the enormous number of DNA base sequence possibilities, which has kept the activation information shrouded.
Now, with the help of artificial intelligence, researchers have identified a DNA activation code that's used at least as frequently as the TATA box in humans. Their discovery, which they termed the downstream core promoter region (DPR), could eventually be used to control gene activation in biotechnology and biomedical applications.
The researchers made a pool of 500,000 random versions of DNA sequences and evaluated the DPR activity of each. From there, 200,000 versions were used to create a machine learning model that could accurately predict DPR activity in human DNA.
These results clearly revealed the existence of the DPR motif in human genes. Moreover, the frequency of occurrence of the DPR appears to be comparable to that of the TATA box. In addition, they observed an intriguing duality between the DPR and TATA. Genes that are activated with TATA box sequences lack DPR sequences, and vice versa.
Identification of the human DPR core promoter element using machine learning, Nature (2020). DOI: 10.1038/s41586-020-2689-7 , www.nature.com/articles/s41586-020-2689-7
https://phys.org/news/2020-09-machine-aids-gene-discovery.html?utm_...
Sep 10, 2020
Dr. Krishna Kumari Challa
Sound waves replace human hands in petri dish experiments
Mechanical engineers have demonstrated a set of prototypes for manipulating particles and cells in a Petri dish using sound waves. The devices, known in the scientific community as "acoustic tweezers," are the first foray into making these types of tools, which have thus far been relegated to laboratories with specific equipment and expertise, available for use in a wide array of settings.
Acoustic tweezers are a powerful, versatile set of tools that use sound waves to manipulate bioparticles ranging from nanometer-sized extracellular vesicles to millimeter-sized multicellular organisms. Over the past several decades, the capabilities of acoustic tweezers have expanded from simplistic particle trapping to the precise rotation and translation of cells and organisms in three dimensions.
"Generating multifunctional acoustic tweezers in Petri dishes for contactless, precise manipulation of bioparticles" Science Advances (2020). DOI: 10.1126/sciadv.abb0494
https://phys.org/news/2020-09-human-petri-dish.html?utm_source=nwle...
Sep 10, 2020
Dr. Krishna Kumari Challa
Nobel prize-winning economics of climate change is misleading and dangerous – here’s why
https://theconversation.com/nobel-prize-winning-economics-of-climat...
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https://phys.org/news/2020-09-australia-environmental-scientists-si...
How Australia's environmental scientists are being silenced
https://theconversation.com/research-reveals-shocking-detail-on-how...
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How Bermuda Triangle became a mystery ....
https://theconversation.com/curious-kids-what-is-the-bermuda-triang...
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Nine mistakes we make about the pandemic
From false dichotomies — save lives or save the economy? — to the ‘prevention paradox’ that breeds complacency when public-health measures work, many of us suffer from conceptual errors when it comes to coronavirus.
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Space Could Be Littered With Eerie Transparent Stars Made Entirely of Bosons
https://www.sciencealert.com/there-could-be-transparent-stars-made-...
Sep 10, 2020
Dr. Krishna Kumari Challa
The Most Common Pain Relief Drug in The World Induces Risky Behaviour, Study Suggests
Acetaminophen, also known as paracetamol and sold widely under the brand names Tylenol and Panadol, also increases risk-taking, according to a new study that measured changes in people's behaviour when under the influence of the common over-the-counter medication.
https://academic.oup.com/scan/advance-article/doi/10.1093/scan/nsaa...
https://www.sciencealert.com/the-most-common-pain-relief-drug-in-th...
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Researchers document the 'life cycle' of a volcano
https://phys.org/news/2020-09-document-life-volcano.html?utm_source...
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German study highlights carbon footprint of video streaming
https://phys.org/news/2020-09-german-highlights-carbon-footprint-vi...
Sep 10, 2020
Dr. Krishna Kumari Challa
Quirky response to magnetism presents quantum physics mystery
https://phys.org/news/2020-09-quirky-response-magnetism-quantum-phy...
https://www.quora.com/q/sciencecommunication/Quirky-response-to-mag... - check %%
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Researchers reveal a much richer picture of the past with new DNA recovery technique
Researchers at McMaster University have developed a new technique to tease ancient DNA from soil, pulling the genomes of hundreds of animals and thousands of plants—many of them long extinct—from less than a gram of sediment.
The DNA extraction method, outlined in the journal Quarternary Research, allows scientists to reconstruct the most advanced picture ever of environments that existed thousands of years ago.
The researchers analyzed permafrost samples from four sites in the Yukon, each representing different points in the Pleistocene-Halocene transition, which occurred approximately 11,000 years ago.
This transition featured the extinction of a large number of animal species such as mammoths, mastodons and ground sloths, and the new process has yielded some surprising new information about the way events unfolded, say the researchers.
Tyler J. Murchie et al, Optimizing extraction and targeted capture of ancient environmental DNA for reconstructing past environments using the PalaeoChip Arctic-1.0 bait-set, Quaternary Research (2020). DOI: 10.1017/qua.2020.59
https://phys.org/news/2020-09-reveal-richer-picture-dna-recovery.ht...
Sep 11, 2020
Dr. Krishna Kumari Challa
At least 28 extinctions prevented by conservation action in recent decades
Conservation action has prevented the global extinction of at least 28 bird and mammal species since 1993, a study has shown.
The species include Puerto Rican Amazon Amazona vittata, Przewalski's Horse Equus ferus, Alagoas Antwren Myrmotherula snowi, Iberian Lynx Lynx pardinus, and Black Stilt Himantopus novaezelandiae, among others.
an international team of scientists have estimated the number of bird and mammal species that would have disappeared forever without the efforts of conservationists in recent decades.
The researchers found that 21-32 bird and 7-16 mammal species extinctions have been prevented since 1993, with the ranges reflecting the uncertainty inherent in estimating what might have happened under hypothetical circumstances.
Bolam, F.C, Mair, L., Angelico, M., Brooks, T.M, Burgman, M., McGowan, P. J. K & Hermes, C. et al. (2020). How many bird and mammal extinctions has recent conservation action prevented? Conservation Letters (2020). DOI: 10.1111/conl.12762
https://phys.org/news/2020-09-extinctions-action-decades.html?utm_s...
Sep 11, 2020
Dr. Krishna Kumari Challa
Study finds humans are behind costly, increasing risk of wildfire to millions of homes
People are starting almost all the wildfires that threaten U.S. homes, according to an innovative new analysis combining housing and wildfire data. Through activities like debris burning, equipment use and arson, humans were responsible for igniting 97% of home-threatening wildfires, a University of Colorado Boulder-led team reported this week in the journal Fire.
Nathan Mietkiewicz et al, In the Line of Fire: Consequences of Human-Ignited Wildfires to Homes in the U.S. (1992–2015), Fire (2020). DOI: 10.3390/fire3030050
https://phys.org/news/2020-09-humans-costly-wildfire-millions-homes...
Sep 11, 2020
Dr. Krishna Kumari Challa
Big 'particle accelerator' in the sky!
The Earth's magnetic field traps high-energy particles. When the first satellites were launched into space, scientists led by James Van Allen unexpectedly discovered the high-energy particle radiation regions, which were later named after its discoverer: the Van Allen Radiation Belts. Visualized, these look like two donut-shaped regions encompassing the planet.
Now, a new study led by researchers from GFZ German Research Center for Geosciences shows that electrons in the radiation belts can be accelerated to very high speeds locally. The study shows that magnetosphere works as a very efficient particle accelerator, speeding up electrons to so-called ultra-relativistic energies.
To better understand the origin of the Van Allen Belts, in 2012, NASA launched the Van Allen Probes twin spacecraft to traverse this most harsh environment and conduct detailed measurements in this hazardous region. The measurements included a full range of particles moving at different speeds and in different directions, and plasma waves. Plasma waves are similar to the waves that we see on the water surface, but are invisible to the naked eye. They can be compared to ripples in the electric and magnetic field.
Recent observations revealed that the energy of electrons in the belts can go up to so called ultra-relativistic energies. These electrons, with temperatures above 100 billion degrees Fahrenheit, move so quickly that their energy of motion is much higher than their energy of rest given by Einstein's famous formula E=mc2. They are so fast that the time significantly slows down for these particles.
Scientists were surprised to find these ultra-relativistic electrons and assumed that such high energies can be only reached by a combination of two processes: the inward transport of particles from the outer regions of the magnetosphere, which accelerates them, and a local acceleration of particles by plasma waves.
However, the new study shows that electrons reach such incredible energies locally, in the heart of the belts, by taking all this energy from plasma waves. This process turns out to be extremely efficient. The unexpected discovery of how acceleration of particles to ultra-relativistic energies operates in the near-Earth space may help scientists understand the fundamental processes of acceleration on the sun, near outer planets, and even in the distant corners of the universe, where space probes cannot reach.
Hayley Allison, Yuri Shprits: "Local heating of radiation belt electrons to ultra-relativistic energies" Nature Communications, DOI: 10.1038/s41467-020-18053-z
https://phys.org/news/2020-09-giant-particle-sky.html?utm_source=nw...
Sep 11, 2020
Dr. Krishna Kumari Challa
The Astounding Fact About The Universe - Neil Degrasse Tyson
How do vaccines work?
Sep 11, 2020
Dr. Krishna Kumari Challa
"Using noise to fight noise":
Sick of city din? Try 'noise-cancelling headphones' for your flat
https://techxplore.com/news/2020-09-sick-city-din-noise-cancelling-...
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5 ways our immune responses to COVID vaccines are unique
https://theconversation.com/5-ways-our-immune-responses-to-covid-va...
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Carbon-rich exoplanets may be made of diamonds
When stars and planets are formed, they do so from the same cloud of gas, so their bulk compositions are similar. A star with a lower carbon to oxygen ratio will have planets like Earth, comprised of silicates and oxides with a very small diamond content (Earth's diamond content is about 0.001%).
But exoplanets around stars with a higher carbon to oxygen ratio than our sun are more likely to be carbon-rich.Researchers hypothesized that these carbon-rich exoplanets could convert to diamond and silicate, if water (which is abundant in the universe) were present, creating a diamond-rich composition.
H. Allen-Sutter et al, Oxidation of the Interiors of Carbide Exoplanets, The Planetary Science Journal (2020). DOI: 10.3847/PSJ/abaa3e
https://phys.org/news/2020-09-carbon-rich-exoplanets-diamonds.html?...
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Sep 11, 2020
Dr. Krishna Kumari Challa
Terroir: can a crop’s environment shape a food’s smell and taste? Scientists explore whether terroir leaves a lasting imprint
https://www.sciencenews.org/article/terroir-food-crops-environment-...
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More than 90% of protected areas are disconnected
https://phys.org/news/2020-09-areas-disconnected.html?utm_source=nw...
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To repair a damaged heart, three cells are better than one
https://medicalxpress.com/news/2020-09-heart-cells.html?utm_source=...
Sep 11, 2020
Dr. Krishna Kumari Challa
Infection higher in hospital cleaners than ICU staff: report
Intensive care medics were significantly less likely to have been infected with COVID-19 than cleaners and other healthcare workers in departments deemed lower risk, according to a study of several British hospitals at the peak of the pandemic.
The research also found that people of black, Asian and minority ethnicity were nearly twice as likely to have been infected as white colleagues.
It follows several studies suggesting race, income and allocation of personal protective equipment (PPE) create biases in the burden of infections.
Researchers said the results could be because those working in intensive therapy units (ITU) were prioritised for the highest level of masks and other equipment.
SARS-CoV-2 seroprevalence and asymptomatic viral carriage in healthcare workers: a cross-sectional study, Thorax (2020). DOI: 10.1136/thoraxjnl-2020-215414
https://medicalxpress.com/news/2020-09-infection-higher-hospital-cl...
Sep 12, 2020
Dr. Krishna Kumari Challa
Researchers quantify worldwide loss of phosphorus due to soil erosion for the first time
Phosphorus is essential for agriculture, yet this important plant nutrient is increasingly being lost from soils around the world. The primary cause is soil erosion, reports an international research team.
The world's food production depends directly on phosphorus. However, this plant nutrient is not unlimited, originating from finite geological reserves.
Erosion flushes mineral-bound phosphorus out of agricultural soils into wetlands and water bodies, where the excess of nutrients (called eutrophication) harms the aquatic plant and animal communities. The researchers were able to validate their calculations using globally published measurement data on phosphorus content in rivers: The elevated phosphorus content in waters mirrors the calculated loss of phosphorus in the soil in the respective region.
Mineral fertilizers can replace the lost phosphorus in the fields, but not all countries are equally able to use them.
Christine Alewell et al. Global phosphorus shortage will be aggravated by soil erosion, Nature Communications (2020). DOI: 10.1038/s41467-020-18326-7
https://phys.org/news/2020-09-quantify-worldwide-loss-phosphorus-du...
Sep 12, 2020
Dr. Krishna Kumari Challa
https://www.livescience.com/65117-do-elephant-tusks-or-rhino-horns-....
Do Elephant Tusks or Rhino Horns Ever Grow Back?
Elephant tusks do not grow back, but rhino horns do.
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scientists have developed a non-invasive technique for unraveling the complex dynamics generated by spinal cord circuits to unprecedented detail, a first in functional magnetic resonance imaging that may one day help diagnose spinal cord dysfunction or injury.
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Children born to mothers who had diabetes during pregnancy may age faster biologically and be at an increased risk for obesity and high blood pressure
Sep 12, 2020
Dr. Krishna Kumari Challa
Computational modelling explains why blues and greens are brightest colous in nature
Researchers have shown why intense, pure red colors in nature are mainly produced by pigments, instead of the structural color that produces bright blue and green hues.
The researchers, from the University of Cambridge, used a numerical experiment to determine the limits of matt structural color—a phenomenon which is responsible for some of the most intense colors in nature—and found that it extends only as far as blue and green in the visible spectrum. The results, published in PNAS, could be useful in the development of non-toxic paints or coatings with intense color that never fades.
Structural color, which is seen in some bird feathers, butterfly wings or insects, is not caused by pigments or dyes, but internal structure alone. The appearance of the color, whether matt or iridescent, will depending on how the structures are arranged at the nanoscale.
Ordered, or crystalline, structures result in iridescent colors, which change when viewed from different angles. Disordered, or correlated, structures result in angle-independent matt colors, which look the same from any viewing angle. Since structural color does not fade, these angle-independent matt colors would be highly useful for applications such as paints or coatings, where metallic effects are not wanted.
In addition to their intensity and resistance to fading, a matt paint which uses structural color would also be far more environmentally-friendly, as toxic dyes and pigments would not be needed.
Gianni Jacucci et al, The limitations of extending nature's color palette in correlated, disordered systems, Proceedings of the National Academy of Sciences (2020). DOI: 10.1073/pnas.2010486117
https://phys.org/news/2020-09-blues-greens-brightest-colous-nature....
Sep 12, 2020
Dr. Krishna Kumari Challa
How plants ensure regular seed spacing
https://phys.org/news/2020-09-regular-seed-spacing.html?utm_source=...
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Could there be a form of life inside stars?
https://phys.org/news/2020-09-life-stars.html?utm_source=nwletter&a...
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Wildlife in 'catastrophic decline' due to human destruction, scientists warn
https://www.bbc.com/news/science-environment-54091048?utm_source=Na...
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The Science Behind Mysterious Orange Skies
https://www.forbes.com/sites/marshallshepherd/2020/09/10/the-scienc...
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Dark matter clumps in galaxy clusters bend light surprisingly well
Not only is the mysterious substance invisible, but it’s also not all where we thought it was
https://www.sciencenews.org/article/dark-matter-clumps-galaxy-clust...
Sep 12, 2020
Dr. Krishna Kumari Challa
Halving the risk of infection following surgery
Surgeons could dramatically reduce the risk of infection after an operation by simply changing the antiseptic they use.
New analysis by the University of Leeds and the University of Bern of more than 14,000 operations has found that using alcoholic chlorhexidine gluconate (CHG) halves the risk of infection in certain types of surgery when compared to the more commonly used povidone-iodine (PVI).
Infection after surgery could result in a range of issues including readmission to hospital and possibly further surgery.
https://www.eurekalert.org/pub_releases/2020-09/uol-htr091120.php
Sep 12, 2020
Dr. Krishna Kumari Challa
Filtering out toxic chromium from water
Sep 13, 2020
Dr. Krishna Kumari Challa
What We Don't Know About Parasites in Our Changing World Could Be Deadly
https://www.sciencealert.com/what-we-don-t-know-about-parasites-in-...
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Robot takes contact-free measurements of patients' vital signs
Sep 13, 2020
Dr. Krishna Kumari Challa
Opening eyes to a frontier in vision restoration
researchers have developed miniaturised, wireless electronic implants that sit on the surface of the brain and have the capacity to restore vision.
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Living Planet report reveals 68% decline in global wildlife populat...
The WWF’s Living Planet Report 2020 presents a comprehensive overview of the state of our natural world as captured by the Living Planet Index (LPI). Almost 21,000 populations of over 4,000 vertebrate species were tracked between 1970 and 2016, with contributions from over 125 experts from around the world.
The Living Planet Report 2020 underlines how humanity’s increasing destruction of nature is having catastrophic impacts not only on wildlife populations, but on human health and all aspects of our lives.
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There’s no evidence that blue-light blocking glasses help with sleep
https://theconversation.com/theres-no-evidence-that-blue-light-bloc...
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The Fate of Schrödinger's Cat Probably Isn't in The Hands of Gravity, Experiment Finds
https://www.sciencealert.com/new-experiment-shows-the-fate-of-schro...
Sep 14, 2020
Dr. Krishna Kumari Challa
Math Shows How Famed Indus Valley Civilization May Have Been Toppled by Climate Change
There are competing hypotheses around the decline of the Indus Valley Civilization in South Asia some 3,000 years ago, but a new mathematical proof has identified that climate change could have been responsible.
Mathematical scientist Nishant Malik from the Rochester Institute of Technology crunched the numbers and found new evidence to back up the idea that shifting monsoon seasons and increasing drought might have helped bring about the collapse of the Bronze Age empire.
By analysing the presence of a particular isotope in stalagmites in a North Indian cave – which should reveal the amount of water that fell as rain over time – scientists have previously been able to estimate monsoon rainfall in the region over the past 5,700 years.
In the new research, Malik was able to identify patterns in this data showing a major shift in monsoon patterns as the civilization began to rise, and then a reverse shift that matched its decline.
Uncovering transitions in paleoclimate time series and the climate driven demise of an ancient civilization
Sep 14, 2020
Dr. Krishna Kumari Challa
New fossil ape is discovered in India
A 13-million-year-old fossil unearthed in northern India comes from a newly discovered ape, the earliest known ancestor of the modern-day gibbon. The discovery fills a major void in the ape fossil record and provides important new evidence about when the ancestors of today's gibbon migrated to Asia from Africa. This discovery fills major gaps in the hominoid fossil record.
The fossil, a complete lower molar, belongs to a previously unknown genus and species (Kapi ramnagarensis) and represents the first new fossil ape species discovered at the famous fossil site of Ramnagar, India, in nearly a century.
New Middle Miocene Ape (Primates: Hylobatidae) from Ramnagar, India Fills Major Gaps in the Hominoid Fossil Record, Proceedings of the Royal Society B (2020). rspb.royalsocietypublishing.or … .1098/rspb.2020.1655
https://phys.org/news/2020-09-fossil-ape-india.html?utm_source=nwle...
Sep 14, 2020
Dr. Krishna Kumari Challa
Ancient volcanoes once boosted ocean carbon, but humans are now far outpacing them
https://phys.org/news/2020-09-ancient-volcanoes-boosted-ocean-carbo...
https://www.quora.com/q/sciencecommunication/Ancient-volcanoes-once...; - check%%
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Gene-edited livestock 'surrogate sires' successfully made fertile
For the first time, scientists have created pigs, goats and cattle that can serve as viable "surrogate sires," male animals that produce sperm carrying only the genetic traits of donor animals.
could speed the spread of desirable characteristics in livestock and improve food production for a growing global population. It also would enable breeders in remote regions better access to genetic material of elite animals from other parts of the world and allow more precision breeding in animals such as goats where using artificial insemination is difficult.
Michela Ciccarelli el al., "Donor-derived spermatogenesis following stem cell transplantation in sterile NANOS2 knockout males," PNAS (2020). www.pnas.org/cgi/doi/10.1073/pnas.2010102117
https://phys.org/news/2020-09-gene-edited-livestock-surrogate-sires...
Sep 15, 2020
Dr. Krishna Kumari Challa
Hints of life on Venus: Scientists detect phosphine molecules in high cloud decks
An international team of astronomers yesterday (14th sept., 2020) announced the discovery of a rare molecule—phosphine—in the clouds of Venus. On Earth, this gas is only made industrially, or by microbes that thrive in oxygen-free environments.
Astronomers have speculated for decades that high clouds on Venus could offer a home for microbes—floating free of the scorching surface, but still needing to tolerate very high acidity. The detection of phosphine molecules, which consist of hydrogen and phosphorus, could point to this extra-terrestrial 'aerial' life.
To create the observed quantity of phosphine on Venus, terrestrial organisms would only need to work at about 10% of their maximum productivity.
Greaves, J.S., Richards, A.M.S., Bains, W. et al. Phosphine gas in the cloud decks of Venus. Nat Astron (2020). doi.org/10.1038/s41550-020-1174-4
https://phys.org/news/2020-09-hints-life-venus-scientists-phosphine...
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Collective quantum effect: When electrons keep together
https://phys.org/news/2020-09-quantum-effect-electrons.html?utm_sou...
https://www.quora.com/q/sciencecommunication/Collective-quantum-eff...; - check%%
Sep 15, 2020
Dr. Krishna Kumari Challa
Animals' magnetic 'sixth' sense may come from bacteria, new paper suggests
Scientists hypothesis to the Q why some animals have a magnetic 'sixth' sense, such as sea turtles' ability to return to the beach where they were born: the magnetic sense comes from a symbiotic relationship with magnetotactic bacteria.
Magnetotactic bacteria are a special type of bacteria whose movement is influenced by magnetic fields, including the Earth's.
Animals that sense Earth's magnetic field include sea turtles, birds, fish and lobsters. Sea turtles, for example, can use the ability for navigation to return to the beach where they were born.
Learning how organisms interact with magnetic fields can improve humans' understanding of how to use Earth's magnetic fields for their own navigation purposes. It can also inform ecological research into the effects of human modifications of the magnetic environment, such as constructing power lines, on biodiversity. Research into the interaction of animals with magnetic fields can also aid the development of therapies that use magnetism for drug delivery.
In the article, the researchers review the arguments for and against the hypothesis, present evidence published in support that has arisen in the past few years, as well as offer new supportive evidence of their own.
Their new evidence comes from microbes ( Metagenomic Rapid Annotations using Subsystems Technology database), the magnetotactic bacteria that had been found in animal samples. Scientists found for the first time, that magnetotactic bacteria are associated with many animals, including a penguin species, loggerhead sea turtles, bats and Atlantic right whales.
the hypothesis that animals use magnetic bacteria in a symbiotic way to gain a magnetic sense warrants further exploration but still needs more evidence before anything conclusive can be stated.
Eviatar Natan et al, Symbiotic magnetic sensing: raising evidence and beyond, Philosophical Transactions of the Royal Society B: Biological Sciences (2020). DOI: 10.1098/rstb.2019.0595
https://phys.org/news/2020-09-animals-magnetic-sixth-bacteria-paper...
Sep 15, 2020
Dr. Krishna Kumari Challa
Bioactive nano-capsules to hijack cell behaviour to treat diseases
Many diseases are caused by defects in signaling pathways of body cells. In the future, bioactive nanocapsules could become a valuable tool for medicine to control these pathways. Researchers have taken an important step in this direction: They succeed in having several different nanocapsules work in tandem to amplify a natural signaling cascade and influence cell behaviour.
Andrea Belluati et al, Bioactive Catalytic Nanocompartments Integrated into Cell Physiology and Their Amplification of a Native Signaling Cascade, ACS Nano (2020). DOI: 10.1021/acsnano.0c05574
https://phys.org/news/2020-09-bioactive-nano-capsules-hijack-cell-b...
Sep 15, 2020
Dr. Krishna Kumari Challa
Boron nitride nanofilms might replace antibiotics for protection against bacterial and fungal infections
Material scientists have presented antibacterial nano-coatings based on boron nitride, which are highly effective against microbial pathogens (up to 99.99%). They can become a safe alternative to the usual antibiotics in implantology since they do not have typical negative side effects.
Due to the significant increase in the number of surgical procedures around the world, scientists are addressing the problem of microbial infections caused by implants. It is especially serious during orthopedic and dental operations. It is no secret that concomitant drug therapy for inflammation around implants often leads to side effects due to the characteristic properties of the antibiotics, as well as the required high doses.
A group of scientists from has proposed a non-standard solution to the problem by investigating the interaction of antibiotic-resistant gram-negative bacteria Escherichia coli (E.coli) and a nanofilm consisting of a structured boron nitride surface. It turned out that such a coating inactivates 100% of bacterial cells after 24 hours.
Kristina Y. Gudz et al. Pristine and Antibiotic-Loaded Nanosheets/Nanoneedles-Based Boron Nitride Films as a Promising Platform to Suppress Bacterial and Fungal Infections, ACS Applied Materials & Interfaces (2020). DOI: 10.1021/acsami.0c10169
https://phys.org/news/2020-09-boron-nitride-nanofilms-antibiotics-b...
Sep 15, 2020
Dr. Krishna Kumari Challa
Physicists 'trick' photons into behaving like electrons using a 'synthetic' magnetic field
Scientists have discovered an elegant way of manipulating light using a 'synthetic' Lorentz force—which in nature is responsible for many fascinating phenomena including the Aurora Borealis.
A team of theoretical physicists from the University of Exeter has pioneered a new technique to create tuneable artificial magnetic fields, which enable photons to mimic the dynamics of charged particles in real magnetic fields.
The team believe the new research, published in leading journal Nature Photonics, could have important implications for future photonic devices as it provides a novel way of manipulating light below the diffraction limit.
Mann, C., Horsley, S.A.R. & Mariani, E. Tunable pseudo-magnetic fields for polaritons in strained metasurfaces. Nat. Photonics (2020). doi.org/10.1038/s41566-020-0688-8 , www.nature.com/articles/s41566-020-0688-8
https://phys.org/news/2020-09-physicists-photons-electrons-syntheti...
Sep 15, 2020