Scientists achieve breakthrough in culturing corals and sea anemones cells

Researchers have perfected the recipe for keeping sea anemone and coral cells alive in a petri dish for up to 12 days. The new study has important applications to study everything from evolutionary biology to human health.

Cnidarians are emerging model organisms for cell and molecular biology research. Yet, successfully keeping their cells in a laboratory setting has proved challenging due to contamination from the many microorganisms that live within these marine organisms or because the whole tissue survive in a culture environment.

Researchers used two emerging model organisms in developmental and evolutionary biology—the starlet sea anemone (Nematostella vectensis) and cauliflower coral (Pocillopora damicornis)—to find more successful way to grow these cell cultures in a laboratory setting. They tested 175 cell cultures from the two organisms and found that their cells can survive for on average 12 days if they receive an antibiotic treatment before being cultured.

James D. Nowotny et al, Novel methods to establish whole-body primary cell cultures for the cnidarians Nematostella vectensis and Pocillopora damicornis, Scientific Reports (2021). DOI: 10.1038/s41598-021-83549-7

https://phys.org/news/2021-02-scientists-breakthrough-culturing-cor...

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 How reliable are existing studies on microplastics in table salt?

Just as environmentally conscious scientists predicted, our excessive use of plastics is coming back to bite us. Microplastics (MPs), plastic particles smaller than a few millimeters, can now be found everywhere, but more so in seawater. As expected, MPs are harmful to both environment and health, although their exact effects are unclear.

To get a better grasp of the extent of the MP problem, it is necessary to quantify how much we are exposed to them. Table salt has been shown to contain MPs, making it an ideal study target to gauge human exposure to MPs. Although many studies have measured the concentration of MPs in different edible salts, each research group used vastly different methodologies of quantification, causing much variability between the results, and calling into question their validity.

To address this problem, in a study published in the Journal of Hazardous Materials, scientists from Incheon National University, Korea, conducted a systematic review of all published papers on MPs in table salt and analyzed the differences between their methodologies and results in detail.

They found that the concentration of MPs in edible salt according to the literature varied quite a bit, and that measurement and sample-preparation procedures of each study were causing these differences. However, the largest differences were caused by the methods used to identify MPs, the minimum cut-off size and the criteria for the selection of particles. 

When not corrected by different measured minimum MP cutoff sizes, MP content differed from 10 to 600 times among different MP identification methods, with greatest values originating from visual observation and followed by spectroscopy methods

Scientists also found a notable correlation between logarithmic mean abundances of MPs and minimum cut-off size used, regardless of the identification method.

Hee-Jee Lee et al, Variation and Uncertainty of Microplastics in Commercial Table Salts: Critical Review and Validation, Journal of Hazardous Materials (2020). DOI: 10.1016/j.jhazmat.2020.123743

https://phys.org/news/2021-02-salt-reliable-microplastics-table.htm...

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Dancing Roots

Microscopic Wrinkles in Leaves Ward Off Bugs

Crops have advanced a formidable vary of methods to beat back hungry, leaf-chomping bugs. Properly-known defenses embrace foul-tasting toxins, sticky resins and sharp thorns, and now scientists have recognized one more instance: microscopic wrinkles that make leaves more durable to stroll on.

Wrinkles kind in lots of leaves’ cuticles—coatings that restrict water evaporation, mediate gasoline alternate, and shield the plant from pathogens. The brand new analysis, revealed in Royal Society Open Science, finds that together with the cuticle’s inherently slippery floor, its tiny wrinkles additionally assist discourage bugs. The wrinkles most certainly grow to be extra pronounced because the leaf matures and its cuticle builds up, ultimately increasing and buckling.

https://royalsocietypublishing.org/doi/10.1098/rsos.201319

Were it not for humans, woolly mammoths would have lived for 4,000 more years, simulation shows

An international team of researchers has used computer simulations to show that it was likely a combination of climate change and human hunting that led to the extinction of the woolly mammoth. They have written a paper describing their findings, available on the bioRxiv preprint server—in it, they suggest that were it not for human hunters, the mammoths would have lasted another 4,000 years.

the researchers created a simulation showing wooly mammoth populations from approximately 21,000 years ago, to 4,000 years ago—the time when the last of the mammoths died out. To recreate conditions the mammoths faced, the researchers added climate data as well as known human hunting data. They ran their simulation over 90,000 times with slight changes to the factors that might have led to their demise. The simulations showed that the most likely scenario involved climate change pushing the mammoths into smaller environments and hunters finishing them off. Interestingly, the researchers also found that if they removed human hunters from the simulations, the majority of the mammoths held on for another 4,000 years.

 Damien A. Fordham et al. Humans hastened the range collapse and extinction of woolly mammoth, bioRxiv (2021). DOI: 10.1101/2021.02.17.431706

https://phys.org/news/2021-02-humans-woolly-mammoths-years-simulati...

Scientists use Doppler to peer inside cells

Doppler radar improves lives by peeking inside air masses to predict the weather. A Purdue University team is using similar technology to look inside living cells, introducing a method to detect pathogens and treat infections in ways that scientists never have before.

In a new study, the team used Doppler to sneak a peek inside cells and track their metabolic activity in real time, without having to wait for cultures to grow. Using this ability, the researchers can test microbes found in food, water, and other environments to see if they are pathogens, or help them identify the right medicine to treat antibiotic-resistant bacteria.

Researchers worked with immortalized cell lines—cells that will live forever unless you kill them. They exposed the cells to different known pathogens, in this case salmonella and E. coli. They then used the Doppler effect to spy out how the cells reacted. These living cells are called "sentinels," and observing their reactions is called a biodynamic assay.

This strategy is broadly applicable when scientists have isolated an unknown microbe and want to know if it is pathogenic—harmful to living tissues—or not. Such cells may show up in food supply, water sources or even in recently melted glaciers.

Another benefit is the ability to quickly and directly diagnose which bacteria respond to which antibiotics.

 Honggu Choi et al, Doppler imaging detects bacterial infection of living tissue, Communications Biology (2021). DOI: 10.1038/s42003-020-01550-8

https://phys.org/news/2021-02-scientists-doppler-peer-cells.html?ut...

https://www.youtube.com/watch?v=mwr-wF_IMeU

https://www.youtube.com/watch?v=9nzkF0hmy04

https://www.youtube.com/watch?v=I1Bdp2tMFsY

Study suggests habitat loss is leading to inbreeding of Indian tigers

While Indian tigers have the highest genetic variation compared to other subspecies of the feline across the world, their populations continue to be fragmented by loss of habitat, leading to inbreeding and potential loss of this diversity, says a new study.

 Habitat loss from human activities leads to tigers being "hemmed into their own protected area. Now, they can only mate with the other tigers in their own population. Over time, this will result in inbreeding, they will end up mating with their relatives. This  inbreeding might compromise their fitness and their ability to survive.

While genetic diversity across a population improves their chances of survival in the future, the study said population fragmentation of tigers can decrease this variation, and endanger them further.

https://academic.oup.com/mbe/advance-article/doi/10.1093/molbev/msa...

In the study, the scientists sequenced whole genomes from 65 individual tigers from four subspecies of the feline, and conducted a variety of population genomic analyses that quantify genetic variability. They investigated the partitioning of genetic variation, possible impacts of inbreeding, and demographic history, and possible signatures of local adaptation.

While the total genomic variation in Indian tigers was higher than in other subspecies, the study found that several individual tigers in the country had low variation, suggesting possible inbreeding.

https://www.thehindu.com/sci-tech/energy-and-environment/study-sugg...

How an ancient virus spread the ability to remember

A protein in your brain behaves like a virus, infecting your cells with memories

Forming a protective shell, Arc moves from neuron to neuron

X-factor to help antibiotics regain their spark

Researchers find a single-celled slime mold with no nervous system that remembers food locations

Having a memory of past events enables us to take smarter decisions about the future. Researchers now identified the basis for forming memories in the slime mold Physarum polycephalum—despite its lack of a nervous system.

The ability to store and recover information gives an organism a clear advantage when searching for food or avoiding harmful environments, and has been traditionally linked to organisms that have a nervous system. A new study challenges this view by uncovering the surprising abilities of a highly dynamic,single-celled organism to store and retrieve information about its environment.

The slime mold Physarum polycephalum has been puzzling researchers for many decades. Existing at the crossroads between the kingdoms of animals, plants and fungi, this unique organism provides insight into the early evolutionary history of eukaryotes. Its body is a giant single cell made up of interconnected tubes that form intricate networks. This single amoeba-like cell may stretch several centimeters or even meters, featuring as the largest cell on earth in the Guinness Book of World Records.

The striking abilities of the slime mold to solve complex problems such as finding the shortest path through a maze earned it the attribute "intelligent," intrigued the research community and kindled questions about decision making on the most basic levels of life. The decision-making ability of Physarum is especially fascinating given that its tubular network constantly undergoes fast reorganization—growing and disintegrating its tubes—while completely lacking an organizing center. The researchers discovered that the organism weaves memories of food encounters directly into the architecture of the network-like body and uses the stored information when making future decisions.

Researchers followed the migration and feeding process of the organism and observed a distinct imprint of a food source on the pattern of thicker and thinner tubes of the network long after feeding. Given P. polycephalum's highly dynamic network reorganization, the persistence of this imprint sparked the idea that the network architecture itself could serve as memory of the past.

The researchers combined microscopic observations of the adaption of the tubular network with theoretical modeling. An encounter with food triggers the release of a chemical that travels from the location where food was found throughout the organism and softens the tubes in the network, making the whole organism reorient its migration towards the food.

The gradual softening is where the existing imprints of previous food sources come into play and where information is stored and retrieved. Past feeding events are embedded in the hierarchy of tube diameters, specifically in the arrangement of thick and thin tubes in the network. For the softening chemical that is now transported, the thick tubes in the network act as highways in traffic networks, enabling quick transport across the whole organism. Previous encounters imprinted in the network architecture weigh into the decision about the future direction of migration.

Mirna Kramar et al. Encoding memory in tube diameter hierarchy of living flow network, Proceedings of the National Academy of Sciences (2021). DOI: 10.1073/pnas.2007815118

https://phys.org/news/2021-02-single-celled-slime-mold-nervous-food...

Caterpillar silences tomato's cry for help, scientists find

"Silencing the alarm."

Scientists found that a caterpillar called the tomato fruit worm not only chomps on tomatoes and their leaves, but also deposits enzyme-laden saliva on the plant, interfering with its ability to cry for help.

 It has been shown time and time again that when under attack, plants can emit chemical distress signals, causing their peers to mount some sort of defense. A classic example is the smell of a freshly mown lawn, which prompts the release of protective compounds in nearby blades of grass that have yet to be cut.

In some cases, plant distress signals can even summon help from other species. That's what happens with the tomato. When caterpillars nibble on the plant's leaves, the leaf pores release volatile chemicals that are detected by a type of parasite: a wasp that lays eggs inside caterpillars. 

So can the caterpillars strike back? In a series of experiments, researchers found that the answer was yes, illustrating a previously unknown strategy in nature's age-old contest between predator and prey.

The key is the enzyme in the caterpillar's saliva, which inhibits the opening of pores in tomato-plant leaves. That means the leaves are less able to release the distress signals, and presumably less able to attract wasps that could come to the rescue.

 Po‐An Lin et al. Silencing the alarm: an insect salivary enzyme closes plant stomata and inhibits volatile release, New Phytologist (2021). DOI: 10.1111/nph.17214

https://phys.org/news/2021-02-horror-movie-caterpillar-silences-tom...

Swift Links Neutrino to Star-destroying Black Hole

https://fb.watch/3Yp8kldIDt/

A single male lyrebird can mimic the sound of an entire flock

The masters of imitation appear to have vocal talents more profound than previously appreciated

Coronavirus transmission through the placenta: Baby infected with coronavirus in the womb

A pregnant woman with suspected COVID-19 was rushed by ambulance to Skåne University Hospital, in Malmo, Sweden, suffering from sudden severe abdominal pain. The doctors noticed that the unborn infant had an abnormally low heart rate, which can be a sign that the baby is not getting enough oxygen.

The doctors performed an emergency caesarean section and delivered the baby within minutes. Blood tests from the baby confirmed it had severely low oxygen, and throat swabs showed that both mother and baby were suffering from COVID.

Using throat swabs from the mother and the newborn, the genome of the virus was sequenced to confirm the possibility that the infant had been infected with COVID while still in the womb.

 a few days later, new genetic sequencing showed that the baby’s virus population had changed and contained a mutated version of the virus along with the original virus strain from the mother. To the best of our knowledge, this is the first case of a genetic change of the coronavirus in the unique setting of mother-to-foetus transmission before birth.

Although it is common for viruses to mutate, this mutation (called A107G) happened just five days after the baby was delivered. The genetic changes may have been stimulated by the baby coming in contact with the external environment outside the mother’s womb. However, it was surprising how quickly this single mutation occurred.

The most important findings were the changes seen in the placenta. The placenta takes blood and nutrients to the foetus and takes away waste and is critical for the growth and wellbeing of the foetus. Half the tissue was damaged. There was widespread inflammation, and  coronavirus protein was found on both the mother’s and foetus’s side of the placenta. Also found was coronavirus protein in all areas that were damaged by inflammation.

 with thousands of pregnant women infected worldwide, mother-to-baby transmission in the womb seems to be a rare complication of COVID during pregnancy.

Scientists think that this is because of the placental barrier that protects the baby in the womb from most infections. Also, the vital receptor needed for coronavirus entry into cells, called an ACE-2 receptor, only exists in low levels in the placenta.

In rare cases, coronavirus can damage the placenta – leading to a lack of oxygen in the unborn child – even if the mother has a mild case of COVID in late pregnancy. 

we should rethink how we monitor pregnant women who have COVID, and they should be considered a more important risk group than we do today.

https://theconversation.com/baby-infected-with-coronavirus-in-the-w...

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Carbon Capture Research 

Huge, Global Study of Plastic Toys Finds Over 100 Substances That May Harm Children

The potential health risks of chemicals used in plastic toys have had scientists concerned for years, but new research reveals just how widespread the risk of harm to children remains.

In an international study, researchers assessed the chemical compositions of toys and estimated levels of human exposure to the substances, ultimately finding over 100 "Chemicals of Concern" in plastic toy materials that could pose a non-negligible health risk to children.

Out of 419 chemicals found in hard, soft, and foam plastic materials used in children toys, researchers identified 126 substances that can potentially harm children's health either via cancer or non-cancer effects, including 31 plasticisers, 18 flame retardants, and 8 fragrances.

According to the researchers, while laws in many countries regulate the use of certain potentially toxic chemicals in plastic toys, there is no consistent approach internationally, and current protections don't adequately prohibit the vast extent of potentially harmful substances that toys are made from

In addition, some toxic and banned additives are still found in plastic toys also on regulated markets, for example in case of recycling contaminated plastics, unawareness by producers, or absence of regulations in the producing country.

https://www.sciencedirect.com/science/article/pii/S0160412020321498

https://www.sciencealert.com/plastic-toy-study-finds-over-100-subst...

Biomass-based plastics

The Oldest Known Mummification 'Recipe' Has Been Unearthed, And It's Intense

In an exciting discovery, researchers have discovered an original 'how to' manual, hidden inside an ancient text, which explains the crucial steps to embalming and creating a mummy.

The guide to mummification has been found on a 3,500-year-old piece of papyrus called the Papyrus Louvre-Carlsberg manuscript, so called because half of it, primarily containing medical information.

Among the details that Schiødt has teased out of the document is a list of instructions for embalming the face of the deceased person, which was done with a piece of red linen coated in a special plant-based solution.

The solution included aromatic substances as well as binders for holding the mixture together, and the saturated cloth was intended to keep the face protected from insects and bacteria while also smelling sweet. This process hasn't been documented before, but does match up with some of the mummified remains that have been found.

This manuscript also lays out the full 70-day schedule for embalming, split into two halves: a 35-day drying period and a 35-day wrapping period, which were themselves divided into four-day intervals. Common treatments to the body included applying a mixture called natron, after the removal of the organs and the brain. 

https://news.ku.dk/all_news/2021/02/ancient-egyptian-manual-reveals...

https://www.sciencealert.com/the-oldest-known-mummification-recipe-...

People Are Accidentally Poisoning Themselves Trying to Treat COVID With a Horse Drug

People are trying to treat and prevent COVID-19 by taking ivermectin, a medication commonly used to de-worm horses – and they are poisoning themselves in the process.

The buzz around ivermectin has been generated by the FLCCC, the Front Line COVID-19 Critical Care Alliance (FLCCC), which formed at the start of the pandemic. It comprises critical care workers who previously bonded over the controversial use of vitamin C for sepsis, MedPage Today reported.

US regulators say there is not enough robust evidence or safety data to recommend ivermectin as a cure, treatment, or preventative medicine for COVID-19.

While the FLCCC has held press conferences saying studies show the drug could fight against the novel coronavirus, public health agencies and many experts say the research is lacking. 

Ivermectin can be tolerated in small doses but can poison an adult in large quantities 

https://www.businessinsider.com.au/coronavirus-people-are-accidenta...

Structure and dynamics of key receptor in migraine pain determined, paving way for better treatment options

A research team determined the shape and kinetics of an important cell surface (membrane) receptor called calcitonin gene-related peptide (CGRP), which has long been implicated in migraine. The researchers  determined the structure of the receptor alone and in combination with its natural target molecule (CGRP). This gives us a clear understanding of how the receptor works during its normal function in the body. The work has been published in the journal Science.

Future studies will expand the investigations towards potential drug targets.

Tracy M. Josephs et al. Structure and dynamics of the CGRP receptor in apo and peptide-bound forms, Science (2021). DOI: 10.1126/science.abf7258

Migraine is more than a simple headache; more than 3 million migraineurs—more than 60% of whom are women—have at least one attack per year. A smaller subset experience chronic migraine, defined by migraine pain that occurs 15 days or more per month, for three or months in a row. While sufferers experience many different symptoms of varying intensity—usually nausea, dizziness, sensitivity to light and sound, and intense pain on one or both sides of the head—the physiological process of migraine onset and pain is different from other types of headache, such as muscle tension or sinus pain. While migraine was long believed to be a neurovascular disorder that involved dilation of vessels in the skull, face and cerebral membrane, research has excluded vasodilation as a factor in this type of pain. More recent work has identified increased CGRP in the trigeminal se... that results in headache.

https://medicalxpress.com/news/2021-03-dynamics-key-receptor-migrai...

Animals fake death for long periods to escape predators

Many animals feign death to try to escape their predators, with some individuals in prey species remaining motionless, if in danger, for extended lengths of time.

Charles Darwin recorded a beetle that remained stationary for 23 minutes—however the University of Bristol has documented an individual antlion larvae pretending to be dead for an astonishing 61 minutes. Of equal importance, the amount of time that an individual remains motionless is not only long but unpredictable. This means that a predator will be unable to predict when a potential prey item will move again, attract attention, and become a meal.

Predators are hungry and cannot wait indefinitely. Similarly, prey may be losing opportunities to get on with their lives if they remain motionless for too long. Thus, death-feigning might best be thought of as part of a deadly game of hide and seek in which prey might gain most by feigning death if alternative victims are readily available.

The study, published today in science journal Biology Letters, involved evaluating the benefits of death-feigning in terms of a predator visiting small populations of conspicuous prey. Researchers used computer simulations that utilise the marginal value theorem, a classical model in optimization.

 Hide-and-seek strategies and post-contact immobility, Biology Letters (2021). royalsocietypublishing.org/doi … .1098/rsbl.2020.0892

https://phys.org/news/2021-03-animals-fake-death-periods-predators....

Color blindness-correcting contact lenses

Imagine seeing the world in muted shades—gray sky, gray grass. Some people with color blindness see everything this way, though most can't see specific colors. Tinted glasses can help, but they can't be used to correct blurry vision. And dyed contact lenses currently in development for the condition are potentially harmful and unstable. Now, in ACS Nano, researchers report infusing contact lenses with gold nanoparticles to create a safer way to see colors.

Color blindness-correcting contact lenses

Imagine seeing the world in muted shades—gray sky, gray grass. Some people with color blindness see everything this way, though most can't see specific colors.

Now researchers report infusing contact lenses with gold nanoparticles to create a safer way to see colors.

Some daily activities, such as determining if a banana is ripe, selecting matching clothes or stopping at a red light, can be difficult for those with colour blindness. Most people with this genetic disorder have trouble discriminating red and green shades, and red-tinted glasses can make those colors more prominent and easier to see. However, these lenses are bulky and the lens material cannot be made to fix vision problems. Thus, researchers have shifted to the development of special tinted contact lenses. Although the prototype hot-pink dyed lenses improved red-green color perception in clinical trials, they leached dye, which led to concerns about their safety. Gold nanocomposites are nontoxic and have been used for centuries to produce "cranberry glass" because of the way they scatter light. 

To make the contact lenses, the researchers evenly mixed gold nanoparticles into a hydrogel polymer, producing rose-tinted gels that filtered light within 520-580 nm, the wavelengths where red and green overlap. The most effective contact lenses were those with 40 nm-wide gold nano particles, because in tests, these particles did not clump or filter more color than necessary. In addition, these lenses had water-retention properties similar to those of commercial ones and were not toxic to cells growing in petri dishes in the lab. Finally, the researchers directly compared their new material to two commercially available pairs of tinted glasses, and their previously developed hot-pink dyed contact lens. The gold nanocomposite lenses were more selective in the wavelengths they blocked than the glasses. The new lenses matched the wavelength range of the dyed contact lenses, suggesting the gold nanocomposite ones would be suitable for people with red-green color issues without the potential safety concerns. The researchers say that the next step is to conduct clinical trials with human patients to assess comfort.

Ahmed E. Salih et al. Gold Nanocomposite Contact Lenses for Color Blindness Management, ACS Nano (2021). DOI: 10.1021/acsnano.0c09657

https://phys.org/news/2021-03-blindness-correcting-contact-lenses.h...

How 'green' are environmentally friendly fireworks?

Fireworks are used in celebrations around the world, including Independence Day in the U.S., the Lantern Festival in China and the Diwali Festival in India. However, the popular pyrotechnic displays emit large amounts of pollutants into the atmosphere, sometimes causing severe air pollution. Now, researchers reporting in ACS' Environmental Science & Technology have estimated that, although so-called environmentally friendly fireworks emit 15-65% less particulate matter than traditional fireworks, they still significantly deteriorate air quality.

Environmentally friendly fire works aren’t really that friendly!

Fireworks are used in celebrations around the world. However, the popular pyrotechnic displays emit large amounts of pollutants into the atmosphere, sometimes causing severe air pollution. Now, researchers reporting in ACS' Environmental Science & Technology have estimated that, although so-called environmentally friendly fireworks emit 15-65% less particulate matter than traditional fireworks, they still significantly deteriorate air quality.

Fireworks displays can cause health problems, such as respiratory ailments, because they release high levels of air pollutants, including particulate matter (PM), sulfur dioxide, heavy metals and perchlorates. As a result, some cities have banned their use. But because the displays are an important aspect of many traditional celebrations, researchers and manufacturers have tried to develop more environmentally friendly pyrotechnics, including those with smokeless charges and sulfur-free propellants. Although research suggests that these fireworks emit less pollutants, their impact on air quality has not been evaluated.

Now researchers wanted to see how green these fire works are.

The researchers estimated emissions of PM2.5, which is PM with a diameter of 2.5 μm and smaller, from the 160,000 environmentally friendly fireworks set off during the display, as well as emissions from traditional fireworks. They used information on the wind direction, wind speed, temperature and chemical composition of the fireworks to simulate the size, trajectory and peak PM2.5 values for the smoke plume resulting from the event. Then, they compared their simulated values with actual data on PM2.5 concentrations measured at 75 monitoring stations throughout the city following the fireworks display.

In agreement with the team's predictions, the data showed that the fireworks smoke plume began as a narrow band that traveled northward before being fully dispersed, with peak PM2.5 levels similar to the predictions. The researchers used their validated simulation to estimate that the use of environmentally friendly fireworks produces a much smaller, shorter-lasting plume, with 15-65% of the PM2.5 emissions of a display using traditional fireworks. However, the peak concentration of PM2.5 still greatly exceeds WHO guidelines.

This led the researchers to conclude that the number of "green" fireworks used at one time should be restricted.

"Are Environmentally Friendly Fireworks Really "Green" for Air Quality? A Study from the 2019 National Day Fireworks Display in Shenzhen" Environmental Science & Technology (2021). pubs.acs.org/doi/abs/10.1021/acs.est.0c03521

Expect more extreme short-duration thunderstorms caused by global w...

Climate experts have revealed that rising temperatures will intensify future rainfall extremes at a much greater rate than average rainfall, with largest increases to short thunderstorms.

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How do you know where volcanic ash will end up?

When the Eyjafjallajökull volcano in Iceland erupted in April 2010, air traffic was interrupted for six days and then disrupted until May. Until then, models from the nine Volcanic Ash Advisory Centres (VAACs) around the world, which aimed at predicting when the ash cloud interfered with aircraft routes, were based on the tracking of the clouds in the atmosphere.

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New approach to removing toxins from wastewater

The New York State Center for Clean Water Technology (CCWT) at Stony Brook University has made a series of critical discoveries regarding a new approach to protecting Long Island's drinking water, groundwater, and surface waters. Some of the discoveries involve the likely human carcinogen, 1,4-dioxane, which has been found at higher levels in Long Island drinking water than anywhere else in the U.S.

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Think all your plastic is being recycled? New research shows it can...

We all know it's wrong to toss your rubbish into the ocean or another natural place. But it might surprise you to learn some plastic waste ends up in the environment, even when we thought it was being recycled.

Think all your plastic is being recycled? New research shows it can end up in the ocean

Some plastic waste ends up in the environment, even when we thought it was being recycled. Plastic waste most commonly leaks into the environment at the country to which it's shipped. Plastics which are of low value to recyclers, such as lids and polystyrene foam containers, are most likely to end up polluting the environment.

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Plastic waste collected for recycling is often sold for reprocessing in Asia. There, the plastics are sorted, washed, chopped, melted and turned into flakes or pellets. These can be sold to manufacturers to create new products.

The global recycled plastics market is dominated by two major plastic types:

polyethylene terephthalate (PET), which in 2017 comprised 55% of the recyclable plastics market. It's used in beverage bottles and takeaway food containers and features a "1" on the packaging

high-density polyethylene (HDPE), which comprises about 33% of the recyclable plastics market. HDPE is used to create pipes and packaging such as milk and shampoo bottles, and is identified by a "2."

The next two most commonly traded types of plastics, each with 4% of the market, are:

• polypropylene or "5," used in containers for yoghurt and spreads
• low-density polyethylene known as "4," used in clear plastic films on packaging.

The remaining plastic types comprise polyvinyl chloride (3), polystyrene (6), other mixed plastics (7), unmarked plastics and "composites." Composite plastic packaging is made from several materials not easily separated, such as long-life milk containers with layers of foil, plastic and paper.

This final group of plastics is not generally sought after as a raw material in manufacturing, so has little value to recyclers.

https://theconversation.com/think-all-your-plastic-is-being-recycle...

Coronavirus: what happens when a person is simultaneously infected with two variants?

Scientists in Brazil recently reported that two people were simultaneously infected with two different variants of SARS-CoV-2, the virus that causes COVID-19. This co-infection seemed to have no effect on the severity of patients’ illness, and both recovered without needing to be hospitalised.

Although this is one of the few such cases recorded with SARS-CoV-2 – and the study is yet to be published in a scientific journal – scientists have observed infections with multiple strains with other respiratory viruses, such as influenza. This has raised questions about how these viruses may interact in an infected person, and what it could mean for generating new variants.

The detection of multiple variants in a person could be the result of co-infection by the different variants, or the generation of mutations within the patient after the initial infection. One way to discriminate these two scenarios is by comparing the sequences of the variants circulating in the population with those in the patient. In the Brazilian study mentioned above, the variants identified corresponded to different lineages that had been previously detected in the population, implying co-infection by the two variants.

It is important to note that this requires the two viruses to infect the same cell. Even if a person is infected with several variants, if they replicate in different parts of the body, they will not interact with each other. Indeed, this was seen in patients, where different quasi-species of coronaviruses were found in the upper and lower respiratory tracts, suggesting that viruses in these sites were not directly mixing with each other.

The evidence so far does not suggest that infection with more than one variant leads to more severe disease. And although possible, very few cases of co-infection have been reported. More than 90% of the infections in the UK currently are by B117 – the so-called Kent variant. With such a high prevalence of one variant in the population, co-infections are not likely to occur. Still, monitoring this landscape allows scientists to track the emergence of these new variants of concern and understand and respond to any changes in their transmission or vaccine efficacy.

https://theconversation.com/coronavirus-what-happens-when-a-person-...

Velcro-like cellular proteins key to tissue strength

 Where do bodily tissues get their strength? New CU Boulder research provides important new clues to this long-standing mystery, identifying how specialized proteins called cadherins join forces to make cells stick and stay stuck together. The findings, publishing this week in the Proceedings of the National Academy of Sciences, could lead to more life-like artificial tissues and tumor busting drugs. Better understanding these proteins allows for the design of more effective engineered tissues that better mimic biological materials as well as cancer therapeutics that are more efficient and target-specific.

For example: If a cancer treatment could block a specific interaction of these cadherin proteins, it could potentially slow tumor growth by stopping or slowing the formation of new blood vessels in tumors.

Cadherin proteins are important in our bodies because they facilitate the binding and adhesion of cells in neural, cardiac, placental and skin tissues, among others, helping them maintain their function and shape.

These large, rod-like proteins in the cell membrane mediate information between the inside and outside of the cell. Where they stick out, they can bond with other cadherin proteins from the same cell, as well as those from other cells.

Like Velcro, the study found, the more pieces stick together, the stronger the bond and the longer it lasts. This amplified strength not only between proteins which exist on the same cell, but between proteins located on different cells—creating bonds 30 times stronger than the sum of their individual strengths. And once the bonding begins, these bonds become progressively stronger and stronger.

https://www.pnas.org/content/118/10/e2019845118

https://www.colorado.edu/today/2021/03/01/velcro-cellular-proteins-...

Researchers discover new way to halt excessive inflammation

Researchers have discovered a new way to 'put the brakes' on excessive inflammation by regulating a type of white blood cell that is critical for our immune system. The discovery has the potential to protect the body from unchecked damage caused by inflammatory diseases.

Excessive inflammation is a prominent feature of many diseases such as multiple sclerosis, arthritis and inflammatory bowel diseases.

When immune cells (white blood cells) in our body called macrophages are exposed to potent infectious agents, powerful inflammatory proteins known as cytokines are produced to fight the invading infection. However, if these cytokine levels get out of control, significant tissue damage can occur.

The researchers have found that a protein called Arginase-2 works through the energy source of macrophage cells, known as mitochondria, to limit inflammation. Specifically they have shown for the first time that Arginase-2 is critical for decreasing a potent inflammatory cytokine called IL-1.

This discovery could allow researchers to develop new treatments that target the Arginase-2 protein and protect the body from unchecked damage caused by inflammatory diseases.

Nature Communications (2021). DOI: 10.1038/s41467-021-21617-2

https://medicalxpress.com/news/2021-03-halt-excessive-inflammation....

'Fungal ghosts' protect skin, fabric from toxins, radiation

The idea of creating selectively porous materials has captured the attention of chemists for decades. Now, new research from Northwestern University shows that fungi may have been doing exactly this for millions of years.

When scientists set out to synthesize melanin that would mimic that which was formed by certain fungi known to inhabit unusual, hostile environments including spaceships, dishwashers and even Chernobyl, they did not initially expect the materials would prove highly porous— a property that enables the material to store and capture molecules.

 Journal of the American Chemical Society 

https://phys.org/news/2021-03-fungal-ghosts-skin-fabric-toxins.html...

An intelligent soft material that curls under pressure or expands when stretched

This is a fact!

Many women complain that they 're not being considered or overlooked for awards and prizes including the Nobel prize (1) in science just because of their gender. I recently found an interesting thing. I got a national award for science communication. During the award giving ceremony, Indian science and Tech secretary told us an interesting story.

Department of Science and Technology, India, gives prizes for the best PhD write up to train and make the budding scientists better at science communication. This year, they removed the names before sending the articles for assessment. And magic, magic, magic, magic. All the prize winners are women! Not even a single man got it.

What did we learn from it? Patriarchal mindsets are definitely impeding womens' chances of winning awards and prizes in science! Once you change the situation where there is no way to learn for the judge whether the person who is being judged is male or female, there is a better chance for women to win!

Footnotes:

1. Why more women don’t win Nobel prizes in science

Eyeless roundworms sense color
Roundworms don't have eyes or the light-absorbing molecules required to see. Yet, new research shows they can somehow sense color. The study, published on March 5 in the journal Science, suggests worms use this ability to assess the risk of feasting on potentially dangerous bacteria that secrete blue toxins. The researchers pinpointed two genes that contribute to this spectral sensitivity and are conserved across many organisms, including humans.
So a 1 mm tiny worm, Caenorhabditis elegans, with neither eyes nor the molecular machinery used by eyes to detect colors can identify and avoid a toxic bacterium based, in part, on its blue color! They can smell, taste, sense touch, react to temperature, and even escape or change their feeding patterns in response to bright, blue light.

https://news.mit.edu/2021/eyeless-roundworms-sense-color-0304

Scientists read 300-year-old letters without opening them

The letters had been folded using a mysterious technique.

Unopened letters more than 300 years old that were folded using mysterious techniques have now been read for the first time without opening them, a new study finds.

For centuries, before mass-produced envelopes started proliferating in the 1830s, most letters across the globe were sent using letterlocking, a method of folding letters to become their own envelopes. These intricate techniques also often served to help recipients detect if mail had been tampered with.

For example, during research in the Vatican Secret Archives, conservator Jana Dambrogio at the MIT Libraries unearthed Renaissance letters with odd slits and sliced-off corners. She discovered these were signs these documents were originally locked with a slice of paper slid through a slit and closed with a wax seal. Such letters could not be opened without ripping the paper, which would reveal to intended recipients if someone else had read the letters first.

After studying 250,000 historical letters, Dambrogio and her colleagues devised the first system to categorize letterlocking techniques, a kind of periodic table based on how these strategies creased sheets. "Letterlocking is a 10,000-year-old technology -- as long as people have tried to build security into their correspondences, you've had letterlocking, from cuneiform tablets all the way to bitcoin paper wallets.

Until now, scientists could only read these "letterpackets" by cutting them open, often damaging the documents. Although such work naturally focused on the letter's contents, this came at the cost of research into letterlocking itself, about which much remains unknown. "These folding sequences, they're just like a sneeze -- they're ephemeral. The minute you open them, you lose evidence of them.

Now scientists have devised a way to both read letterlocked texts without opening them and reconstruct the complex folds, tucks and slits used to secure them. 

The scientists investigated the Brienne Collection, a postmaster's trunk holding more than 3,000 undelivered letters, including 577 letterpackets that were never opened. The letters were sent from all over Europe to The Hague between 1680 and 1706, the era that saw the Salem witch trials unfold, Newton reveal his laws of motion and gravitation, and Louis XIV move his court to Versailles.

The researchers first analyzed four letterpackets with high-resolution X-ray scans to generate 3D models of the documents. Next, they used a new computational algorithm to identify and separate different layers of the folded letters and recognize text written on them. Finally, the algorithm virtually unfolded the letters, not only making the writing visible, but also recording the crease patterns so the researchers could re-create the letterlocking process step by step.

This new strategy helped the scientists read unopened letterlocked text for the first time. 

https://www.nature.com/articles/s41467-021-21326-w

Scientists discover why blood type may matter for COVID infection

A new study provides further evidence that people with certain blood types may be more likely to contract COVID-19.

Specifically, it found that the new coronavirus (SARS-CoV-2) is particularly attracted to the blood group A antigen found on respiratory cells.

The researchers focused on a protein on the surface of the SARS-CoV-2 virus called the receptor binding domain (RBD), which is the part of the virus that attaches to the host cells. That makes it an important target for scientists trying to learn how the virus infects people.

In this laboratory study, the team assessed how the SARS-CoV-2 RBD interacted with respiratory and red blood cells in A, B and O blood types.

The results showed that the SARS-CoV-2 RBD had a strong preference for binding to blood group A found on respiratory cells, but had no preference for blood group A red blood cells, or other blood groups found on respiratory or red cells.

The SARS-CoV-2 RBD's preference to recognize and attach to the blood type A antigen found in the lungs of people with blood type A may provide insight into the potential link between blood group A and COVID-19 infection, according to the authors of the study. It was published March 3 in the journal Blood Advances.

https://ashpublications.org/bloodadvances/article/5/5/1305/475250/T...

https://medicalxpress.com/news/2021-03-scientists-blood-covid-infec...

Astrocytes derived from patients with bipolar disorder malfunction

Brain cells called astrocytes derived from the induced pluripotent stem cells of patients with bipolar disorder offer suboptimal support for neuronal activity. In a paper in the journal Stem Cell Reports, researchers show that this malfunction can be traced to an inflammation-promoting molecule called interleukin-6 (IL-6), which is secreted by astrocytes. The results highlight the potential role of astrocyte-mediated inflammatory signaling in the psychiatric disease, although further investigation is needed.

Artificial ‘brain’ reveals why we can’t always believe our eyes

Researchers have captured the first detailed images of newborn babies’ lungs as they take their first breaths.

Economic benefits of protecting nature now outweigh those of exploiting it, global data reveal

The economic benefits of conserving or restoring natural sites "outweigh" the profit potential of converting them for intensive human use, according to the largest-ever study comparing the value of protecting nature at particular locations with that of exploiting it.

A research team  analysed dozens of sites—from Kenya to Fiji and China to the UK—across six continents. A previous breakthrough study in 2002 only had information for five sites.

For the latest study, scientists calculated the monetary worth of each site's "ecosystem services", such as carbon storage and flood protection, as well as likely dividends from converting it for production of goods such as crops and timber.

The team initially concentrated on 24 sites and compared their "nature-focused" and "alternative" states by working out the annual net value of a range of goods and services for each site under each state, then projected the data over the next 50 years.

A major economic benefit of natural habitats comes from their regulation of the greenhouse gases driving climate change, including the sequestration of carbon.

 The economic consequences of conserving or restoring sites for nature, Nature Sustainability (2021). DOI: 10.1038/s41893-021-00692-9 , dx.doi.org/10.1038/s41893-021-00692-9

https://phys.org/news/2021-03-economic-benefits-nature-outweigh-exp...

Do photosynthetic complexes use quantum coherence to increase their...

In a new report now published on Science Advances, Elinor Zerah Harush and Yonatan Dubi in the departments of chemistry and nanoscale science and technology, at the Ben-Gurion University of the Negev, Israel, discussed a direct evaluation of the effects of quantum coherence on the efficiency of three natural photosynthetic complexes. The open quantum systems approach allowed the researchers to simultaneously identify the quantum-nature and efficiency under natural physiological conditions. These systems resided in a mixed quantum-classical regime, which they characterized using dephasing-assisted transport. The efficiency was minimal at best therefore the presence of quantum coherence did not play a substantial role in the process. The efficiency was also independent of any structural parameters, suggesting the role of evolution during structural design for other uses.

--

How the growth of ice depends on the fluid dynamics underneath

Researchers of the Toschi group of Eindhoven University of Technology think the water phase change problem with considering the water density anomaly is of great importance relating to common natural phenomena. Their research plan is firstly to understand the physics fundamentals, that is, the coupled problem of the stably and unstably stratified layers with considering the density anomaly.

At Dubai airport, travelers' eyes become their passports

Dubai's airport, the world's busiest for international travel, can already feel surreal, with its cavernous duty-free stores, artificial palm trees, gleaming terminals, water cascades and near-Arctic levels of air conditioning.

Now, the key east-west transit hub is rolling out another addition from the realm of science fiction—an iris-scanner that verifies one's identity and eliminates the need for any human interaction when entering or leaving the country.

That's because the airport debuted a new "smart tunnel" that uses biometric technology, instead of human checks, to allow some air travelers to complete passport control in just 15 seconds.

It's the latest artificial intelligence program the United Arab Emirates has launched amid the surging coronavirus pandemic, contact-less technology the government promotes as helping to stem the spread of the virus. But the efforts also have renewed questions about mass surveillance in the federation of seven sheikhdoms, which experts believe has among the highest per capita concentrations of surveillance cameras in the world.

Dubai's airport started offering the program to all passengers last month. On Sunday, travelers stepped up to an iris scanner after checking in, gave it a good look and breezed through passport control within seconds. Gone were the days of paper tickets or unwieldy phone apps.

In recent years, airports across the world have accelerated their use of timesaving facial recognition technology to move passengers to their flights. But Dubai's iris scan improves on the more commonplace automated gates seen elsewhere, authorities said, connecting the iris data to the country's facial recognition databases so the passenger needs no identifying documents or boarding pass.

Now, all the procedures have become 'smart,' around five to six seconds

 Iris biometrics are considered more reliable than surveillance cameras that scan people's faces from a distance without their knowledge or consent.

https://techxplore.com/news/2021-03-dubai-airport-eyes-passports.ht...

https://phys.org/news/2018-10-dubai-airport-biometric-tech.html

How to cut onions without crying using science

Humidity in breath makes cotton masks more effective at slowing the spread of COVID-19

Researchers have come up with a better way to test which fabrics work best for masks that are meant to slow the spread of COVID-19. By testing those fabrics under conditions that mimic the humidity of a person's breath, the researchers have obtained measurements that more accurately reflect how the fabrics perform when worn by a living, breathing person.

The new measurements show that under humid conditions, the filtration efficiency—a measure of how well a material captures particles—increased by an average of 33% in cotton fabrics. Synthetic fabrics performed poorly relative to cotton, and their performance did not improve with humidity. The material from medical-procedure masks also did not improve with humidity, though it performed in roughly the same range as cottons.

The filtration efficiency of cotton fabrics increases in humid conditions because cotton is hydrophilic, meaning it likes water. By absorbing small amounts of the water in a person's breath, cotton fibers create a moist environment inside the fabric. As microscopic particles pass through, they absorb some of this moisture and grow larger, which makes them more likely to get trapped.

Most synthetic fabrics, on the other hand, are hydrophobic, meaning they dislike water. These fabrics do not absorb moisture, and their filtration efficiency does not change in humid conditions.

Christopher D. Zangmeister et al, Hydration of Hydrophilic Cloth Face Masks Enhances the Filtration of Nanoparticles, ACS Applied Nano Materials (2021). DOI: 10.1021/acsanm.0c03319

https://phys.org/news/2021-03-humidity-cotton-masks-effective-covid...

Bacterial film separates water from oil

Researchers have demonstrated that a slimy, yet tough, type of biofilm that certain bacteria make for protection and to help them move around can also be used to separate water and oil. The material may be useful for applications such as cleaning contaminated waters.

They reported the findings of an experiment in which they used a material produced by the bacteria Gluconacetobacter hansenii as a filter to separate water from an oil mixture.

The biofilm the bacteria make and release into their environment is made of cellulose, which is the same material that gives plants a sturdy structure in their cell walls. However, when bacteria make cellulose, it has a tightly packed, crystalline structure. It's one of the purest, if not the purest, forms of cellulose out there. The bacteria make the film to protect themselves.

The material was effective at removing water, and it 's sturdy. The oil doesn't want to go through the membrane; it has a repulsive effect to it. It's super fat-hating.

Researchers see a variety of potential applications for the material in situations where you need to recover water from an oily mixture—whether it be to clean water contaminated with a textile dye or for environmental remediation.

Zahra Ashrafi et al. Bacterial Superoleophobic Fibrous Matrices: A Naturally Occurring Liquid-Infused System for Oil–Water Separation, Langmuir (2021). DOI: 10.1021/acs.langmuir.0c02717

https://phys.org/news/2021-03-bacterial-oil.html?utm_source=nwlette...

How trees secretly talk to each other

Scientists develop new magnetic nanomaterial for counterfeit money prevention

An international research team  has developed a new iron-cobalt-nickel nanocomposite with tunable magnetic properties. The nanocomposite could be used to protect money and securities from counterfeiting. 

The new iron-cobalt-nickel nanocomposite was obtained by chemical precipitation, followed by a reduction process.

The new composite was observed to possess high value of coercivity, which makes the technology applicable e.g. to magnetic rubbers and different magnetically coupled devices. Another potential application is protecting money and securities from counterfeiting.

Tien Hiep Nguyen et al, Impact of Iron on the Fe–Co–Ni Ternary Nanocomposites Structural and Magnetic Features Obtained via Chemical Precipitation Followed by Reduction Process for Various Magnetically Coupled Devices Applications, Nanomaterials (2021). DOI: 10.3390/nano11020341

https://phys.org/news/2021-03-scientists-magnetic-nanomaterial-coun...

Bacteria know how to exploit quantum mechanics, study finds

Photosynthetic organisms harvest light from the sun to produce the energy they need to survive. A new paper published by University of Chicago researchers reveals their secret: exploiting quantum mechanics.

Before this study, the scientific community saw quantum signatures generated in biological systems and asked the question, were these results just a consequence of biology being built from molecules, or did they have a purpose?" said Greg Engel, Professor of Chemistry and senior author on the study. "This is the first time we are seeing biology actively exploiting quantum effects.

The scientists studied a type of microorganism called green sulfur bacteria. These bacteria need light to survive, but even small amounts of oxygen can damage their delicate photosynthetic equipment. So they must develop ways to minimize the damage when the bacterium does encounter oxygen.

To study this process, researchers tracked the movement of energy through a photosynthetic protein under different conditions—with oxygen around, and without.

They found that the bacterium uses a quantum mechanical effect called vibronic mixing to move energy between two different pathways, depending on whether or not there's oxygen around. Vibronic mixing involves vibrational and electronic characteristics in molecules coupling to one another. In essence, the vibrations mix so completely with the electronic states that their identities become inseparable. This bacterium uses this phenomenon to guide energy where it needs it to go.

If there's no oxygen around and the bacterium is safe, the bacterium uses vibronic mixing by matching the energy difference between two electronic states in an assembly of molecules and proteins called the FMO complex, with the energy of the vibration of a bacteriochlorophyll molecule. This encourages the energy to flow through the 'normal' pathway toward the photosynthetic reaction center, which is packed full of chlorophyll.

But if there is oxygen around, the organism has evolved to steer the energy through a less direct path where it can be quenched. (Quenching energy is similar to putting a palm on a vibrating guitar string to dissipate energy.) This way, the bacterium loses some energy but saves the entire system.

Jacob S. Higgins et al, Photosynthesis tunes quantum-mechanical mixing of electronic and vibrational states to steer exciton energy transfer, Proceedings of the National Academy of Sciences (2021). DOI: 10.1073/pnas.2018240118

https://phys.org/news/2021-03-bacteria-exploit-quantum-mechanics.ht...

Face masks are a ticking plastic timebomb

Recent studies estimate that we use an astounding 129 billion face masks globally every month—that is 3 million a minute. Most of them are disposable face masks made from plastic microfibers.

With increasing reports on inappropriate disposal of masks, it is urgent to recognize this potential environmental threat and prevent it from becoming the next plastic problem.

Disposable masks are plastic products, that cannot be readily biodegraded but may fragment into smaller plastic particles, namely micro- and nanoplastics that widespread in ecosystems.

The enormous production of disposable masks is on a similar scale as plastic bottles, which is estimated to be 43 billion per month. However, different from plastic bottles, (of which app. 25 pct. is recycled), there is no official guidance on mask recycle, making it more likely to be disposed of as solid waste

If not disposed of for recycling, like other plastic wastes, disposable masks can end up in the environment, freshwater systems, and oceans, where weathering can generate a large number of micro-sized particles (smaller than 5 mm) during a relatively short period (weeks) and further fragment into nanoplastics (smaller than 1 micrometer).

"A newer and bigger concern is that the masks are directly made from microsized plastic fibers (thickness of ~1 to 10 micrometers). When breaking down in the environment, the mask may release more micro-sized plastics, easier and faster than bulk plastics like plastic bags.

How can you solve it?

Researchers recommend these solutions:

1. Set up mask-only trash cans for collection and disposal
2. consider standardization, guidelines, and strict implementation of waste management for mask wastes
3. replace disposable masks with reusable face masks like cotton masks
4. consider development of biodegradable disposal masks.

Elvis Genbo Xu et al, Preventing masks from becoming the next plastic problem, Frontiers of Environmental Science & Engineering (2021). DOI: 10.1007/s11783-021-1413-7

https://phys.org/news/2021-03-masks-plastic-timebomb.html?utm_sourc...