Patients who suffer heart attack have more micro and nanoplastic in their blood

Nanoplastics in artery clogging

Image credit: American Heart Association

People who suffered a serious heart attack had higher levels of micro- and nanoplastics in their blood compared with patients diagnosed with chronic ischemic heart disease and those with normal blood vessels supplying the heart, according to a study published in the European Heart Journal this week.
Patients with ST-elevation myocardial infarction showed higher prevalence and diversity of micro- and nanoplastics in coronary and peripheral blood than patients with chronic coronary disease or normal coronaries, with polyethylene predominating. Microplastic presence correlated with smoking, long-term PM2.5 exposure, and elevated inflammatory markers, indicating an association between plastic exposure, systemic inflammation, and acute cardiovascular events without establishing causality.
The study also revealed that people who smoke and people exposed to higher levels of air pollution had higher levels of micro- and nanoplastics in their blood.

The researchers say the study adds to growing evidence that environmental pollution may affect cardiovascular health.
Among those who had heart attacks, micro- and nanoplastics were detected in 84% of patients, compared with 40% of patients with chronic ischemic heart disease and 32% of patients with normal coronary arteries. Heart attack patients had a greater variety of plastic types in their blood. The most common type of plastic was polyethylene, which is commonly used in packaging and consumer products.

Patients exposed to higher long-term levels of air pollution (PM2.5/particles measuring 2.5 μm or less in diameter) were more likely to have microplastics in their blood, and smokers were six times more likely to have microplastics in their blood. All patients who smoked and were exposed to higher air pollution levels had plastics in their blood, compared with only 12.5% of patients who did not smoke and were not exposed to higher levels of air pollution.
The findings suggest that smoking might make it easier for micro- and nanoplastics to enter the bloodstream via the lungs. Air pollution may act in a similar way.
The emerging clinical evidence now suggests a potential link between NMPs and cardiovascular disease. In patients undergoing carotid endarterectomy, NMPs were detected within atherosclerotic plaques, and their presence was associated with an increased risk of myocardial infarction, stroke and all-cause mortality.

Micro- and nano-plastics in the coronary circulation and air pollution exposure in ischaemic heart disease presentation, European Heart Journal (2026). DOI: 10.1093/eurheartj/ehag447