Science, Art, Litt, Science based Art & Science Communication

Science Simplified!

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JAI VIGNAN

All about Science - to remove misconceptions and encourage scientific temper

Communicating science to the common people

'To make them see the world differently through the beautiful lense of science'

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WE LOVE SCIENCE HERE BECAUSE IT IS A MANY SPLENDOURED THING

THIS IS A WAR ZONE WHERE SCIENCE FIGHTS WITH NONSENSE AND WINS

“The greatest enemy of knowledge is not ignorance, it is the illusion of knowledge.”

"Being a scientist is a state of mind, not a profession!"

"Science, when it's done right, can yield amazing things".

The Reach of Scientific Research From Labs to Laymen

The aim of science is not only to open a door to infinite knowledge and wisdom but to set a limit to infinite error.

"Knowledge is a Superpower but the irony is you cannot get enough of it with ever increasing data base unless you try to keep up with it constantly and in the right way!" The best education comes from learning from people who know what they are exactly talking about.

Science is this glorious adventure into the unknown, the opportunity to discover things that nobody knew before. And that’s just an experience that’s not to be missed. But it’s also a motivated effort to try to help humankind. And maybe that’s just by increasing human knowledge—because that’s a way to make us a nobler species.

If you are scientifically literate the world looks very different to you.

We do science and science communication not because they are easy but because they are difficult!

“Science is not a subject you studied in school. It’s life. We 're brought into existence by it!"

Links to some important articles :

1. Interactive science series...

a. how-to-do-research-and-write-research-papers-part 13

b. Some Qs people asked me on science and my replies to them...

Part 6, part-10, part-11, part-12, part 14 , part- 8,

part- 1, part-2, part-4, part-5, part-16, part-17, part-18 , part-19 , part-20

part-21 , part-22, part-23, part-24, part-25, part-26, part-27 , part-28

part-29, part-30, part-31, part-32, part-33, part-34, part-35, part-36, part-37,

part-38, part-40, part-41, part-42, part-43, part-44, part-45, part-46, part-47

Part 48, part49, Critical thinking -part 50 , part -51, part-52, part-53

part-54, part-55, part-57, part-58, part-59, part-60, part-61, part-62, part-63

part 64, part-65, part-66, part-67, part-68, part 69, part-70 part-71, part-73 ...

.......306

BP variations during pregnancy part-72

who is responsible for the gender of their children - a man or a woman -part-56

c. some-questions-people-asked-me-on-science-based-on-my-art-and-poems -part-7

d. science-s-rules-are-unyielding-they-will-not-be-bent-for-anybody-part-3-

e. debate-between-scientists-and-people-who-practice-and-propagate-pseudo-science - part -9

f. why astrology is pseudo-science part 15

g. How Science is demolishing patriarchal ideas - part-39

2. in-defence-of-mangalyaan-why-even-developing-countries-like-india need space research programmes

3. Science communication series:

a. science-communication - part 1

b. how-scienitsts-should-communicate-with-laymen - part 2

c. main-challenges-of-science-communication-and-how-to-overcome-them - part 3

d. the-importance-of-science-communication-through-art- part 4

e. why-science-communication-is-geting worse - part 5

f. why-science-journalism-is-not-taken-seriously-in-this-part-of-the-world - part 6

g. blogs-the-best-bet-to-communicate-science-by-scientists- part 7

h. why-it-is-difficult-for-scientists-to-debate-controversial-issues - part 8

i. science-writers-and-communicators-where-are-you - part 9

j. shooting-the-messengers-for-a-different-reason-for-conveying-the- part 10

k. why-is-science-journalism-different-from-other-forms-of-journalism - part 11

l. golden-rules-of-science-communication- Part 12

m. science-writers-should-develop-a-broader-view-to-put-things-in-th - part 13

n. an-informed-patient-is-the-most-cooperative-one -part 14

o. the-risks-scientists-will-have-to-face-while-communicating-science - part 15

p. the-most-difficult-part-of-science-communication - part 16

q. clarity-on-who-you-are-writing-for-is-important-before-sitting-to write a science story - part 17

r. science-communicators-get-thick-skinned-to-communicate-science-wi thout-any-bias - part 18

s. is-post-truth-another-name-for-science-communication-failure?

t. why-is-it-difficult-for-scientists-to-have-high-eqs

u. art-and-literature-as-effective-aids-in-science-communication-and teaching

v.* some-qs-people-asked-me-on-science communication-and-my-replies-to-them

** qs-people-asked-me-on-science-and-my-replies-to-them-part-173

w. why-motivated-perception-influences-your-understanding-of-science

x. science-communication-in-uncertain-times

y. sci-com: why-keep-a-dog-and-bark-yourself

z. How to deal with sci com dilemmas?

A+. sci-com-what-makes-a-story-news-worthy-in-science

B+. is-a-perfect-language-important-in-writing-science-stories

C+. sci-com-how-much-entertainment-is-too-much-while-communicating-sc

D+. sci-com-why-can-t-everybody-understand-science-in-the-same-way

E+. how-to-successfully-negotiate-the-science-communication-maze

4. Health related topics:

a. why-antibiotic-resistance-is-increasing-and-how-scientists-are-tr

b. what-might-happen-when-you-take-lots-of-medicines

c. know-your-cesarean-facts-ladies

d. right-facts-about-menstruation

e. answer-to-the-question-why-on-big-c

f. how-scientists-are-identifying-new-preventive-measures-and-cures-

g. what-if-little-creatures-high-jack-your-brain-and-try-to-control-

h. who-knows-better?

i. mycotoxicoses

j. immunotherapy

k. can-rust-from-old-drinking-water-pipes-cause-health-problems

l. pvc-and-cpvc-pipes-should-not-be-used-for-drinking-water-supply

m. melioidosis

n.vaccine-woes

o. desensitization-and-transplant-success-story

p. do-you-think-the-medicines-you-are-taking-are-perfectly-alright-then revisit your position!

q. swine-flu-the-difficlulties-we-still-face-while-tackling-the-outb

r. dump-this-useless-information-into-a-garbage-bin-if-you-really-ca re about evidence based medicine

s. don-t-ignore-these-head-injuries

t. the-detoxification-scam

u. allergic- agony-caused-by-caterpillars-and-moths

General science:

a.why-do-water-bodies-suddenly-change-colour

b. don-t-knock-down-your-own-life-line

c. the-most-menacing-animal-in-the-world

d. how-exo-planets-are-detected

e. the-importance-of-earth-s-magnetic-field

f. saving-tigers-from-extinction-is-still-a-travail

g. the-importance-of-snakes-in-our-eco-systems

h. understanding-reverse-osmosis

i. the-importance-of-microbiomes

j. crispr-cas9-gene-editing-technique-a-boon-to-fixing-defective-gen

k. biomimicry-a-solution-to-some-of-our-problems

5. the-dilemmas-scientists-face

6. why-we-get-contradictory-reports-in-science

7. be-alert-pseudo-science-and-anti-science-are-on-prowl

8. science-will-answer-your-questions-and-solve-your-problems

9. how-science-debunks-baseless-beliefs

10. climate-science-and-its-relevance

11. the-road-to-a-healthy-life

12. relative-truth-about-gm-crops-and-foods

13. intuition-based-work-is-bad-science

14. how-science-explains-near-death-experiences

15. just-studies-are-different-from-thorough-scientific-research

16. lab-scientists-versus-internet-scientists

17. can-you-challenge-science?

18. the-myth-of-ritual-working

19.science-and-superstitions-how-rational-thinking-can-make-you-work -better

20. comets-are-not-harmful-or-bad-omens-so-enjoy-the-clestial-shows

21. explanation-of-mysterious-lights-during-earthquakes

22. science-can-tell-what-constitutes-the-beauty-of-a-rose

23. what-lessons-can-science-learn-from-tragedies-like-these

24. the-specific-traits-of-a-scientific-mind

25. science-and-the-paranormal

26. are-these-inventions-and-discoveries-really-accidental-and-intuitive like the journalists say?

27. how-the-brain-of-a-polymath-copes-with-all-the-things-it-does

28. how-to-make-scientific-research-in-india-a-success-story

29. getting-rid-of-plastic-the-natural-way

30. why-some-interesting-things-happen-in-nature

31. real-life-stories-that-proves-how-science-helps-you

32. Science and trust series:

a. how-to-trust-science-stories-a-guide-for-common-man

b. trust-in-science-what-makes-people-waver

c. standing-up-for-science-showing-reasons-why-science-should-be-trusted

You will find the entire list of discussions here: http://kkartlab.in/group/some-science/forum

( Please go through the comments section below to find scientific research reports posted on a daily basis and watch videos based on science)

Get interactive...

Please contact us if you want us to add any information or scientific explanation on any topic that interests you. We will try our level best to give you the right information.

Our mail ID: kkartlabin@gmail.com

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Comment by Dr. Krishna Kumari Challa on July 14, 2020 at 6:59am: Human sperm stem cells grown in lab, an early step toward infertility treatment

https://phys.org/news/2020-07-human-sperm-stem-cells-grown.html?utm...

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https://phys.org/news/2020-07-materials-extra-thin-chips.html?utm_s...

New materials for extra thin computer chips

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https://phys.org/news/2020-07-micro-lab-chip-blood-minutes.html?utm...

A micro-lab on a chip detects blood type within minutes

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Comment by Dr. Krishna Kumari Challa on July 14, 2020 at 6:57am: Turning off 'junk DNA' may free stem cells to become neurons

For every cell in the body there comes a time when it must decide what it wants to do for the rest of its life. In an article published in the journal PNAS, NIH researchers report for the first time that ancient viral genes that were once considered "junk DNA" may play a role in this process. The article describes a series of preclinical experiments that showed how some human endogenous retrovirus (HERV-K) genes inscribed into chromosomes 12 and 19 may help control the differentiation, or maturation, of human stem cells into the trillions of neurons that are wired into our nervous systems.

Over the course of evolution, the human genome has absorbed thousands of human endogenous retrovirus genes. As a result, nearly eight percent of the DNA that lines our chromosomes includes remnants of these genes. Although once thought to be inactive, or "junk", recent studies have shown that these genes may be involved in human embryonic development, the growth of some tumors, and nerve damage during multiple sclerosis.

Previously, researchers showed that amyotrophic lateral sclerosis (ALS) may be linked to activation of the HERV-K gene. In this study, the team showed that deactivation of the gene may free stem cells to become neurons.

The researchers performed most of their experiments on blood cells, drawn from healthy volunteers at the NIH's Clinical Center, that they genetically transformed into induced pluripotent stem cells, which can then turn into any cell type in the body. Surprisingly, they found that the surfaces of the stem cells were lined with high levels of HERV-K, subtype HML-2, an envelope protein, that viruses often use to latch onto and infect cells. These proteins progressively disappeared as the cells were served two rounds of "cocktails." One round nudged the cells into an intermediate, neural stem cell state followed by a second round that pushed the cells into finally becoming neurons. The researchers sped up this process by turning off HERV-K, HML-2 genes in the stem cells or by treating the cells with antibodies against the HML-2 protein. In contrast, they delayed neural differentiation by artificially overloading the cells with the HML-2 genes. Finally, the team discovered that interactions on the stem cell surfaces between HML-2 and another immune cell protein called CD98HC may restrain differentiation by triggering internal chemical reactions that are known to control cell growth and tumors. In the future, the team plans to explore how HERV-K genes may shape the wiring of a nervous system.

Wang, T. et al., Regulation of stem cell function and neuronal differentiation by HERV-K via mTOR pathway, PNAS (2020). DOI: 10.1073/pnas.2002427117

https://phys.org/news/2020-07-junk-dna-free-stem-cells.html?utm_sou...

Comment by Dr. Krishna Kumari Challa on July 14, 2020 at 6:48am: Hidden in our genes: Discovering the fate of cell development

As cells develop, changes in how our genes interact determines their fate. Differences in these genetic interactions can make our cells robust to infection from viruses or make it possible for our immune cells to kill cancerous ones.

Understanding how these gene associations work across the development of human tissue and organs is important for the creation of medical treatments for complex diseases as broad as cancer, developmental disorders, or heart disease.

A new technology called single-cell RNA-sequencing has made it possible to study the behavior of genes in human and mammal cells at an unprecedented resolution and promises to accelerate scientific and medical discoveries.

A team of international collaborators from China, the US and the UK, University of Sydney scientists have developed an analytical approach for this single-cell sequencing, which is able to test for broad changes in gene behavior within human tissue. It has been called single-cell higher-order testing, or scHOT.

Published today in Nature Methods, the team has demonstrated the effectiveness of this method by identifying genes in mice whose variability change in cells during embryonic liver development.

scHOT is a powerful new tool that will uncover hidden gene associations in our cells and facilitate the full exploitation of these cutting-edge single-cell technologies to make important biological discoveries.

This research will help to uncover hidden gene associations in our cells providing a new way to view and describe biological complexity.

Investigating higher-order interactions in single-cell data with scHOT, Nature Methods (2020). DOI: 10.1038/s41592-020-0885-x

https://phys.org/news/2020-07-hidden-genes-fate-cell.html?utm_sourc...

Comment by Dr. Krishna Kumari Challa on July 14, 2020 at 6:33am: Human lungs rejected for transplant recovered using novel technique

A multidisciplinary team has demonstrated that injured human donor lungs declined for transplant can be recovered by cross-circulation between the human lung and a xenogeneic host (Connecting donated human lungs to pigs).

The new technique, described in a study published recently in Nature Medicine, has the potential to increase the supply of donor lungs available for transpalnt, saving the lives of people who would otherwise die while waiting on the transplant list.

Lungs are the least-used solid organ for transplant because only 20% of donor lungs are considered to be in sufficient condition for transplantation. If we could improve the 20% acceptance rate and increase it to 40% or 50% acceptance rate, we would essentially eliminate our waitlist and we would actually be able to open up transplantation to more people.

The team proved in earlier published research that a cross-circulation technique using an animal model can not only support but rehabilitate animal lungs for up to four days. The current research extends that success to human lungs considered too damaged for transplant, preserving them for 24 hours using the xenogeneic platform.

Lung disease is the third leading cause of death globally, and transplantation is the only definitive cure for patients who are in the end stage of the disease. The current standard of care for donor lungs is ex vivo lung perfusion (EVLP), a mechanical support system that can preserve lungs for up to eight hours but has limited means to rehabilitate them. The study demonstrated that a lung that failed to improve on EVLP could be rehabilitated using the xenogeneic platform.

The xenogeneic platform offers scientists two immediate research pathways. First, it offers a new option for transplanting lungs previously considered too damaged for transplant. Secondly, the xenogeneic platform allows lungs to be preserved to test further therapeutic interventions as well as investigations in drug discovery, testing and delivery. Further, the cross-circulation platform may be used to recover other human organs and tissue, including livers, hearts and kidneys as well as limbs.

The cross-species cross-circulation allowed a human lung that failed after its six hours of standard perfusion to heal enough to meet transplant requirements and theoretically help a lung patient, though no transplant was done.

For the current experiments, they connected pigs and human lungs with common problems found after donation: swelling from excess fluid, traumatic injury, damage from inhaled gastric fluids. All the organs had gone through six hours of perfusion before being declined for transplant. For the experiments, immune suppression drugs were infused into the pigs to prevent rejection of the human lung.

While connected to the pigs, the organs’ cells and function were monitored. After 24 hours, the lungs had improved and would likely continue to get better, according to the researchers.

Xenogeneic cross-circulation for extracorporeal recovery of injured human lungs , Nature Medicine (2020). DOI: 10.1038/s41591-020-0971-8

https://medicalxpress.com/news/2020-07-human-lungs-transplant-recov...

Comment by Dr. Krishna Kumari Challa on July 13, 2020 at 9:17am: https://www.sciencemag.org/news/2013/04/when-does-your-baby-become-...

When Does Your Baby Become Conscious?

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Why the h-index is a bogus measure of academic impact

$$ https://theconversation.com/why-the-h-index-is-a-bogus-measure-of-a...

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https://phys.org/news/2020-07-scientists-theorized-neutrinoless-pro...

Scientists demonstrate a new experiment in the search for theorized 'neutrinoless' proc

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https://phys.org/news/2020-07-junk-dna-free-stem-cells.html?utm_sou...

Turning off 'junk DNA' may free stem cells to become neurons

For every cell in the body there comes a time when it must decide what it wants to do for the rest of its life. In an article published in the journal PNAS, NIH researchers report for the first time that ancient viral genes that were once considered "junk DNA" may play a role in this process. The article describes a series of preclinical experiments that showed how some human endogenous retrovirus (HERV-K) genes inscribed into chromosomes 12 and 19 may help control the differentiation, or maturation, of human stem cells into the trillions of neurons that are wired into our nervous systems.

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https://phys.org/news/2020-07-power-dna.html?utm_source=nwletter&am...

Power of DNA to store information gets an upgrade

Comment by Dr. Krishna Kumari Challa on July 13, 2020 at 8:43am: People with high cholesterol should eliminate carbs, not saturated fat

** For decades, people diagnosed with familial hypercholesterolemia have been instructed to minimize their consumption of saturated fats to lower cholesterol and reduce their risks of heart disease. But a new study published in the prestigious journal BMJ Evidence-Based Medicine found no evidence to support those claims.

Familial hypercholesterolemia is a genetic disorder that causes people to have cholesterol levels 2-4 times higher than the average person. Organizations, including the American Heart Association, have suggested they avoid eating food from animal sources, such as meat, eggs and cheese, and to avoid coconut oil. An international team of experts on heart disease and diet, including five cardiologists, reviewed dietary guidelines for people with familial hypercholesterolemia. They say they couldn't find any justification for health experts to recommend a low saturated fat diet.

Following a low-carb diet is most effective for people at increased risk of heart disease, such as those who are overweight, hypertensive and diabetic. Their findings are consistent with another paper recently published in the Journal of the American College of Cardiology, which provided strong evidence that food that raises blood sugar, such as bread, potatoes and sweets, should be minimized, rather than tropical oils and animal-based food.

David M Diamond et al, Dietary Recommendations for Familial Hypercholesterolaemia: an Evidence-Free Zone, BMJ Evidence-Based Medicine (2020). DOI: 10.1136/bmjebm-2020-111412

https://medicalxpress.com/news/2020-07-people-high-cholesterol-carb...

Comment by Dr. Krishna Kumari Challa on July 12, 2020 at 1:01pm: Exaggerated risk of transmission of COVID-19 by fomites

Disinfecting surfaces 'not as necessary as we thought'

https://www.cbc.ca/news/health/coronavirus-surfaces-groceries-packa...

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(20)...

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https://www.businessinsider.in/science/environment/news/pink-climat...

Pink is the shade of climate change with mountains and lakes changing colour across the globe

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https://theconversation.com/death-by-irony-the-mystery-of-the-mouse...

‘Death by irony’: The mystery of the mouse that died of smoke inhalation, but went nowhere near a fire

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https://www.news.com.au/technology/science/campaign-begins-to-derai...

Campaign begins to derail COVID-19 vaccination before it’s even developed

Thousands of scientists are working around the clock to find a coronavirus vaccine. At the same time, groups are already trying to derail it.

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https://medicalxpress.com/news/2020-07-complications-covid-von-will...

Complications from COVID-19 may depend on von Willebrand factor in the blood

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** https://medicalxpress.com/news/2020-07-covid-ten-meters.html?utm_so...

Researchers: COVID-19 spreads ten meters or more by breathing

Comment by Dr. Krishna Kumari Challa on July 12, 2020 at 6:29am: Neptune's Moons Are Caught in One of The Strangest Orbits Ever Seen

https://www.sciencealert.com/neptune-s-moons-are-caught-in-one-of-t...

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https://www.sciencealert.com/our-atmosphere-chimes-in-time-with-ast...

Scientists Detect Earth's Atmosphere 'Ringing' Like a Bell

Just as the Moon tugs at our planet's seas, contributing to oceanic tidal waves, it also pulls at our atmosphere along with the Sun, creating waves in the sky.

A new study now demonstrates how some types of 'sky waves' resonate around Earth, much like how sound waves resonate inside a bell.

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https://www.sciencealert.com/scientists-are-planning-to-make-a-sing...

Scientists Are Planning How to Make a Single Authoritative List of All Species

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https://www.the-scientist.com/news-opinion/saliva-tests-how-they-wo...

Saliva Tests: How They Work and What They Bring to COVID-19

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https://www.quantamagazine.org/how-your-heart-influences-what-you-p...

How Your Heart Influences What You Perceive and Fear

The heartbeat and other bodily processes play a surprising role in shaping perception and cognition.

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https://theconversation.com/type-2-diabetes-eating-a-diet-rich-in-f...

Type 2 diabetes: eating a diet rich in fruit and vegetables daily lowers risk, study shows

Comment by Dr. Krishna Kumari Challa on July 11, 2020 at 10:54am: $$The mathematical strategy that could transform coronavirus testing

Four charts show how pooling samples from many people can save time or resources.

https://www.nature.com/articles/d41586-020-02053-6?utm_source=Natur...

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https://massivesci.com/articles/hydrothermal-vent-reactor-geology-m...

Scientists recreated ancient Earth’s ocean hell to figure out how life began

The experiment also suggests that extraterrestrial life could also emerge on Mars, Europa, and Enceladus

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https://massivesci.com/articles/gingko-tree-longevity-gene-activity...

The genes of 600-year-old ginkgo trees are just as active as their teenage counterparts

Ancient trees reveal the secret to their virtual immortality

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https://www.scientificamerican.com/article/climate-denial-spreads-o...

Climate Denial Spreads on Facebook as Scientists Face Restrictions

The company recently overruled its scientific fact-checking group, which had flagged information as misleading

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https://www.scientificamerican.com/article/stingers-have-achieved-o...

Stingers Have Achieved Optimal Pointiness, Physicists Show

A single equation describes the shapes of stingers, spikes and spines throughout the natural world

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