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Comment by Dr. Krishna Kumari Challa on September 28, 2020 at 9:40am

Metformin treatment linked to slowed cognitive decline

Metformin is the first-line treatment for most cases of type 2 diabetes and one of the most commonly prescribed medications worldwide, with millions of individuals using it to optimize their blood glucose levels.

A new research study, conducted over six years 

 has revealed an additional effect: individuals with type 2 diabetes who used metformin experienced slower cognitive decline with lower dementia rates than those who did not use the medication.

The findings provide new hope for a means of reducing the risk of dementia in individuals with type 2 diabetes, and potentially those without diabetes who number nearly 47 million people worldwide.

Diabetes Care (2020). DOI: 10.2337/dc20-0892

https://medicalxpress.com/news/2020-09-metformin-treatment-linked-c...

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Scientists discover why tarantulas come in vivid blues and greens

https://phys.org/news/2020-09-scientists-tarantulas-vivid-blues-gre...

Comment by Dr. Krishna Kumari Challa on September 28, 2020 at 9:30am

Comment by Dr. Krishna Kumari Challa on September 28, 2020 at 9:27am

Ecologists confirm Alan Turing's theory for fairy circles

Fairy circles are one of nature's greatest enigmas and most visually stunning phenomena. An international research team has now, for the first time, collected detailed data to show that Alan Turing's model explains the striking vegetation patterns of the Australian fairy circles. In addition, the researchers showed that the grasses that make up these patterns act as "eco-engineers" to modify their own hostile and arid environment, thus keeping the ecosystem functioning.

Researchers used drone technology, spatial statistics, quadrat-based field mapping, and continuous data-recording from a field-weather station. With the drone and a multispectral camera, the researchers mapped the "vitality status" of the Triodia grasses (how strong and how well they grew) in five one-hectare plots and classified them into high- and low-vitality.

The systematic and detailed fieldwork enabled, for the first time in such an ecosystem, a comprehensive test of the 'Turing pattern' theory. Turing's concept was that in certain systems, due to random disturbances and a 'reaction-diffusion' mechanism, interaction between just two diffusible substances was enough to allow strongly patterned structures to spontaneously emerge. Physicists have used this model to explain the striking skin patterns in zebrafish or leopards for instance.

The data show that the unique gap pattern of the Australian fairy circles, which occur only in a small area east of the town of Newman, emerges from ecohydrological biomass-water feedbacks from the grasses. In fact, the fairy circles—with their large diameters of 4m, clay crusts from weathering and resultant water run-off—are a critical extra source of water for the dryland vegetation. Clumps of grasses increased shading and water infiltration around the nearby roots. With increasing years after fire, they merged more and more at the periphery of the vegetation gaps to form a barrier so that they could maximize their water uptake from the fairy circle's runoff. The protective plant cover of grasses could reduce soil-surface temperatures by about 25°C at the hottest time of the day, which facilitates the germination and growth of new grasses. In summary, the scientists found evidence both at the scale of the landscape and at much smaller scales that the grasses, with their cooperative growth dynamics, redistribute the water resources, modulate the physical environment, and thus function as "ecosystem engineers" to modify their own environment and better cope with the arid conditions.

Stephan Getzin et al, Bridging ecology and physics: Australian fairy circles regenerate following model assumptions on ecohydrological feedbacks, Journal of Ecology (2020). DOI: 10.1111/1365-2745.13493

https://phys.org/news/2020-09-ecologists-alan-turing-theory-austral...

Comment by Dr. Krishna Kumari Challa on September 28, 2020 at 6:59am

Antifungal preventive drugs reduce mortality risk following lung transplantation: Study

The retrospective study, published in the Annals of the American Thoracic Society, is the largest ever to evaluate the effectiveness of antifungal preventive drugs in lung transplant recipients who are particularly susceptible to invasive fungal infections. These infections are associated with a nearly threefold increase in mortality for lung transplant recipients.

The study showed that  the risk of death within the first year posttransplant is about twice as high in patients not receiving antifungal preventive treatment, compared with those receiving treatment.

https://www.atsjournals.org/doi/abs/10.1513/AnnalsATS.202003-267OC

Comment by Dr. Krishna Kumari Challa on September 28, 2020 at 6:16am

White supremacists believe in genetic ‘purity’. Science shows no such thing exists

Science does not support the idea of pure races with ancient origins. In the past few years, genetic sequencing of ancient and modern humans and related species has given us a flood of new information about how human populations have evolved.

The evidence reveals a history of ongoing genetic mingling, due to interbreeding between different populations and even species. Humans from different groups had children together, and even with Neanderthals and members of other now-extinct hominin species.

This mingling occurred constantly in the long process of human migration across the globe. Europeans inhabit one region of a large genetic continuum and are no more or less “pure” than any other population.

https://theconversation.com/white-supremacists-believe-in-genetic-p...

Comment by Dr. Krishna Kumari Challa on September 28, 2020 at 6:02am

Seven Warning Signs of Bogus Science

1. The discoverer pitches the claim directly to the media.

2. The discoverer says that a powerful establishment is trying to suppress his or her work.

3. The scientific effect involved is always at the very limit of detection.

4. Evidence for a discovery is anecdotal.

5. The discoverer says a belief is credible because it has endured for centuries.

6. The discoverer has worked in isolation.

7. The discoverer must propose new laws of nature to explain an observation.

https://quackwatch.org/related/signs/

Comment by Dr. Krishna Kumari Challa on September 28, 2020 at 5:56am

Body fat deep below the surface is a toxic risk, especially for your heart

BMI can’t provide information about the shape and size of potentially dangerous internal fat deposits, known as “visceral fat”. Over recent years it’s become apparent visceral fat can lead to disease, and good fat can turn into toxic fat when there is too much.

Various organs seem to accumulate visceral fat. This can be a problem because it can create and release damaging molecules and hormones into the blood. These are transported in the bloodstream, potentially causing health complications in distant parts of the body.

For example, toxic fat can release proteins that blunt the body’s sensitivity to insulin. Blood glucose levels then rise, potentially causing diabetes in the long term. Visceral fat can also stimulate uncontrolled cell growth and replication, potentially triggering some forms of cancer. A fatty liver is associated with metabolic diseases, and excess kidney fat interferes with the body’s fluid balance.

The heart is especially vulnerable

https://theconversation.com/body-fat-deep-below-the-surface-is-a-to...

Comment by Dr. Krishna Kumari Challa on September 27, 2020 at 10:54am

A Man Has Died After Eating Bags of Black Licorice Daily

A man in Massachusetts died after eating too much black licorice, which contains a compound known to be toxic in large doses, according to a new report. The 54-year-old man was in a fast food restaurant when he suddenly gasped, began shaking and lost consciousness, according to the report Emergency medical personnel found that the man was experiencing ventricular fibrillation, a life-threatening heart rhythm problem. The man received CPR and briefly regained consciousness before being rushed to the hospital. A discussion with the man's family revealed that he had a poor diet, consuming one to two large packages of soft candy every day, and little else. A few weeks earlier, the man had switched from eating red, fruit-flavored candy to black licorice candy. Black licorice often contains a compound called glycyrrhizin, which is derived from licorice root. Consuming too much licorice root or candies flavored with licorice root can be dangerous because glycyrrhizin lowers the body's potassium levels. This, in turn, can lead to high blood pressure and abnormal heart rhythms.

In the man's case, very low potassium levels led to his heart problems. The man received treatment to restore his potassium levels, along with multiple other treatments in the intensive care unit, including being placed on a ventilator. Despite these efforts, the man died 32 hours after arriving at the hospital. 

Although the death is an "extreme case," eating just 2 ounces of black licorice a day for two weeks can cause heart rhythm problems, particularly for people ages 40 and older.

https://www.livescience.com/black-licorice-death.html

https://www.sciencealert.com/man-dies-from-eating-black-licorice-da...

Comment by Dr. Krishna Kumari Challa on September 26, 2020 at 11:05am

Autopsies Show Varied Forms of Heart Damage in COVID-19 Patients

The multifarious nature of the damage means treatments for cardiac issues during infection will require tailored approaches.

https://www.the-scientist.com/news-opinion/autopsies-show-varied-fo...

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Physicists Argue That Black Holes From the Big Bang Could Be the Dark Matter

It was an old idea of Stephen Hawking’s: Unseen “primordial” black holes might be the hidden dark matter. It fell out of favor for decades, but a new series of studies has shown how the theory can work.

https://www.quantamagazine.org/black-holes-from-the-big-bang-could-...

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https://theconversation.com/from-psychopaths-to-everyday-sadists-wh...

Some 6% of people are sadists. Brian Goff/Shutterstock

From psychopaths to ‘everyday sadists’: why do humans harm the harmless

Comment by Dr. Krishna Kumari Challa on September 26, 2020 at 9:57am

Possible signs of life on Venus

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