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Science Simplified!

                       JAI VIGNAN

All about Science - to remove misconceptions and encourage scientific temper

Communicating science to the common people

'To make  them see the world differently through the beautiful lense of  science'

Members: 22
Latest Activity: 3 hours ago

         WE LOVE SCIENCE HERE BECAUSE IT IS A MANY SPLENDOURED THING

     THIS  IS A WAR ZONE WHERE SCIENCE FIGHTS WITH NONSENSE AND WINS                                               

“The greatest enemy of knowledge is not ignorance, it is the illusion of knowledge.”             

                    "Being a scientist is a state of mind, not a profession!"

                  "Science, when it's done right, can yield amazing things".

         The Reach of Scientific Research From Labs to Laymen

The aim of science is not only to open a door to infinite knowledge and                                     wisdom but to set a limit to infinite error.

"Knowledge is a Superpower but the irony is you cannot get enough of it with ever increasing data base unless you try to keep up with it constantly and in the right way!" The best education comes from learning from people who know what they are exactly talking about.

Science is this glorious adventure into the unknown, the opportunity to discover things that nobody knew before. And that’s just an experience that’s not to be missed. But it’s also a motivated effort to try to help humankind. And maybe that’s just by increasing human knowledge—because that’s a way to make us a nobler species.

If you are scientifically literate the world looks very different to you.

We do science and science communication not because they are easy but because they are difficult!

“Science is not a subject you studied in school. It’s life. We 're brought into existence by it!"

 Links to some important articles :

1. Interactive science series...

a. how-to-do-research-and-write-research-papers-part 13

b. Some Qs people asked me on science and my replies to them...

Part 6part-10part-11part-12, part 14  ,  part- 8

part- 1part-2part-4part-5part-16part-17part-18 , part-19 , part-20

part-21 , part-22part-23part-24part-25part-26part-27 , part-28

part-29part-30part-31part-32part-33part-34part-35part-36part-37,

 part-38part-40part-41part-42part-43part-44part-45part-46part-47

Part 48 part49Critical thinking -part 50 , part -51part-52part-53

part-54part-55part-57part-58part-59part-60part-61part-62part-63

part 64, part-65part-66part-67part-68part 69part-70 part-71part-73 ...

.......306

BP variations during pregnancy part-72

who is responsible for the gender of  their children - a man or a woman -part-56

c. some-questions-people-asked-me-on-science-based-on-my-art-and-poems -part-7

d. science-s-rules-are-unyielding-they-will-not-be-bent-for-anybody-part-3-

e. debate-between-scientists-and-people-who-practice-and-propagate-pseudo-science - part -9

f. why astrology is pseudo-science part 15

g. How Science is demolishing patriarchal ideas - part-39

2. in-defence-of-mangalyaan-why-even-developing-countries-like-india need space research programmes

3. Science communication series:

a. science-communication - part 1

b. how-scienitsts-should-communicate-with-laymen - part 2

c. main-challenges-of-science-communication-and-how-to-overcome-them - part 3

d. the-importance-of-science-communication-through-art- part 4

e. why-science-communication-is-geting worse - part  5

f. why-science-journalism-is-not-taken-seriously-in-this-part-of-the-world - part 6

g. blogs-the-best-bet-to-communicate-science-by-scientists- part 7

h. why-it-is-difficult-for-scientists-to-debate-controversial-issues - part 8

i. science-writers-and-communicators-where-are-you - part 9

j. shooting-the-messengers-for-a-different-reason-for-conveying-the- part 10

k. why-is-science-journalism-different-from-other-forms-of-journalism - part 11

l.  golden-rules-of-science-communication- Part 12

m. science-writers-should-develop-a-broader-view-to-put-things-in-th - part 13

n. an-informed-patient-is-the-most-cooperative-one -part 14

o. the-risks-scientists-will-have-to-face-while-communicating-science - part 15

p. the-most-difficult-part-of-science-communication - part 16

q. clarity-on-who-you-are-writing-for-is-important-before-sitting-to write a science story - part 17

r. science-communicators-get-thick-skinned-to-communicate-science-without-any-bias - part 18

s. is-post-truth-another-name-for-science-communication-failure?

t. why-is-it-difficult-for-scientists-to-have-high-eqs

u. art-and-literature-as-effective-aids-in-science-communication-and teaching

v.* some-qs-people-asked-me-on-science communication-and-my-replies-to-them

 ** qs-people-asked-me-on-science-and-my-replies-to-them-part-173

w. why-motivated-perception-influences-your-understanding-of-science

x. science-communication-in-uncertain-times

y. sci-com: why-keep-a-dog-and-bark-yourself

z. How to deal with sci com dilemmas?

 A+. sci-com-what-makes-a-story-news-worthy-in-science

 B+. is-a-perfect-language-important-in-writing-science-stories

C+. sci-com-how-much-entertainment-is-too-much-while-communicating-sc

D+. sci-com-why-can-t-everybody-understand-science-in-the-same-way

E+. how-to-successfully-negotiate-the-science-communication-maze

4. Health related topics:

a. why-antibiotic-resistance-is-increasing-and-how-scientists-are-tr

b. what-might-happen-when-you-take-lots-of-medicines

c. know-your-cesarean-facts-ladies

d. right-facts-about-menstruation

e. answer-to-the-question-why-on-big-c

f. how-scientists-are-identifying-new-preventive-measures-and-cures-

g. what-if-little-creatures-high-jack-your-brain-and-try-to-control-

h. who-knows-better?

i. mycotoxicoses

j. immunotherapy

k. can-rust-from-old-drinking-water-pipes-cause-health-problems

l. pvc-and-cpvc-pipes-should-not-be-used-for-drinking-water-supply

m. melioidosis

n.vaccine-woes

o. desensitization-and-transplant-success-story

p. do-you-think-the-medicines-you-are-taking-are-perfectly-alright-then revisit your position!

q. swine-flu-the-difficlulties-we-still-face-while-tackling-the-outb

r. dump-this-useless-information-into-a-garbage-bin-if-you-really-care about evidence based medicine

s. don-t-ignore-these-head-injuries

t. the-detoxification-scam

u. allergic- agony-caused-by-caterpillars-and-moths

General science: 

a.why-do-water-bodies-suddenly-change-colour

b. don-t-knock-down-your-own-life-line

c. the-most-menacing-animal-in-the-world

d. how-exo-planets-are-detected

e. the-importance-of-earth-s-magnetic-field

f. saving-tigers-from-extinction-is-still-a-travail

g. the-importance-of-snakes-in-our-eco-systems

h. understanding-reverse-osmosis

i. the-importance-of-microbiomes

j. crispr-cas9-gene-editing-technique-a-boon-to-fixing-defective-gen

k. biomimicry-a-solution-to-some-of-our-problems

5. the-dilemmas-scientists-face

6. why-we-get-contradictory-reports-in-science

7. be-alert-pseudo-science-and-anti-science-are-on-prowl

8. science-will-answer-your-questions-and-solve-your-problems

9. how-science-debunks-baseless-beliefs

10. climate-science-and-its-relevance

11. the-road-to-a-healthy-life

12. relative-truth-about-gm-crops-and-foods

13. intuition-based-work-is-bad-science

14. how-science-explains-near-death-experiences

15. just-studies-are-different-from-thorough-scientific-research

16. lab-scientists-versus-internet-scientists

17. can-you-challenge-science?

18. the-myth-of-ritual-working

19.science-and-superstitions-how-rational-thinking-can-make-you-work-better

20. comets-are-not-harmful-or-bad-omens-so-enjoy-the-clestial-shows

21. explanation-of-mysterious-lights-during-earthquakes

22. science-can-tell-what-constitutes-the-beauty-of-a-rose

23. what-lessons-can-science-learn-from-tragedies-like-these

24. the-specific-traits-of-a-scientific-mind

25. science-and-the-paranormal

26. are-these-inventions-and-discoveries-really-accidental-and-intuitive like the journalists say?

27. how-the-brain-of-a-polymath-copes-with-all-the-things-it-does

28. how-to-make-scientific-research-in-india-a-success-story

29. getting-rid-of-plastic-the-natural-way

30. why-some-interesting-things-happen-in-nature

31. real-life-stories-that-proves-how-science-helps-you

32. Science and trust series:

a. how-to-trust-science-stories-a-guide-for-common-man

b. trust-in-science-what-makes-people-waver

c. standing-up-for-science-showing-reasons-why-science-should-be-trusted

You will find the entire list of discussions here: http://kkartlab.in/group/some-science/forum

( Please go through the comments section below to find scientific research  reports posted on a daily basis and watch videos based on science)

Get interactive...

Please contact us if you want us to add any information or scientific explanation on any topic that interests you. We will try our level best to give you the right information.

Our mail ID: kkartlabin@gmail.com

Discussion Forum

How much CO₂ does your flight really produce? How to know if carbon footprint claims are accurate

Started by Dr. Krishna Kumari Challa. Last reply by Dr. Krishna Kumari Challa 5 hours ago. 1 Reply

When two people book the same flight, they can get wildly different carbon footprints from online calculators. Many carbon calculators leave out big chunks of climate impact or rely on oversimplified…Continue

The importance of snakes in our eco-systems

Started by Dr. Krishna Kumari Challa. Last reply by Dr. Krishna Kumari Challa yesterday. 5 Replies

Crawly creepy creatures. Big eyes and protruding tongues. Hissing sounds and hoods in ready to attack poses.What would people do if they came across such things? Take a stick and hit them repeatedly…Continue

Humans are evolved for nature, not cities, say anthropologists

Started by Dr. Krishna Kumari Challa. Last reply by Dr. Krishna Kumari Challa yesterday. 1 Reply

This mismatch is creating lots of problems for us and we need to change our thinking and behaviour.A new paper by evolutionary anthropologists argues that modern life has outpaced human evolution.…Continue

Phytomining: A fern that makes rare earth elements!

Started by Dr. Krishna Kumari Challa. Last reply by Dr. Krishna Kumari Challa Nov 14. 1 Reply

Credit: Environmental Science & Technology (2025). DOI:…Continue

Comment Wall

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You need to be a member of Science Simplified! to add comments!

Comment by Dr. Krishna Kumari Challa on August 12, 2020 at 5:43am

Enzyme discovered in the gut could lead to new disease biomarker

https://phys.org/news/2020-08-enzyme-gut-disease-biomarker.html?utm...

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Immunotherapy-resistant cancers eliminated in mouse study

Immunotherapy has revolutionized cancer treatment by stimulating the patient's own immune system to attack cancer cells, yielding remarkably quick and complete remission in some cases. But such drugs work for less than a quarter of patients because tumors are notoriously adept at evading immune assault.

A new study in mice by researchers  has shown that the effects of a standard immunotherapy drug can be enhanced by blocking the protein TREM2, resulting in complete elimination of tumors. The findings, which are published Aug. 11 in the journal Cell, point to a potential new way to unlock the power of immunotherapy for more .

Cell (2020). DOI: 10.1016/j.cell.2020.07.013

https://medicalxpress.com/news/2020-08-immunotherapy-resistant-canc...

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 Using physics to improve root canal efficiency

https://phys.org/news/2020-08-physics-root-canal-efficiency.html?ut...

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Research exposes new vulnerability for SARS-CoV-2

https://phys.org/news/2020-08-exposes-vulnerability-sars-cov-.html?...

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 Making masks and PPE with hydrophilic surfaces, could reduce infection risk

https://phys.org/news/2020-08-masks-ppe-hydrophilic-surfaces-infect...

Comment by Dr. Krishna Kumari Challa on August 12, 2020 at 5:41am

How boundaries become bridges in evolution

There's a paradox within the theory of evolution: The life forms that exist today are here because they were able to change when past environments disappeared. Yet, organisms evolve to fit into specific environmental niches.

Ever-increasing specialization and precision should be an evolutionary dead end, but that is not the case. How the ability to fit precisely into a current setting is reconciled with the ability to change is the most fundamental question in evolutionary biology. There are two general possible solutions, according to researchers. First, the mechanisms that enable organisms to fit well into their current environment and the mechanisms that enable change in adaptations are distinct—the latter are suppressed as organisms fit better and better into their current setting and activated only when the environment changes. The second is that the mechanisms that make organisms fit into current environments are themselves modified during evolution.

Distinguishing between these possibilities is challenging because in  we necessarily study processes that occurred in the past, the events that we missed. So, instead, we infer what we missed from comparisons of species that exist today. Although this approach can tell us how well the current organisms fit into their current environment, it cannot tell us how they got here."

Ultimately, the first scenario was supported by the researchers' work. The mechanisms that make organisms locally fit and those responsible for change are distinct and occur sequentially in evolution.

 Ahva L. Potticary et al, Turning induced plasticity into refined adaptations during range expansion, Nature Communications (2020). DOI: 10.1038/s41467-020-16938-7

https://phys.org/news/2020-08-boundaries-bridges-evolution.html?utm...

Comment by Dr. Krishna Kumari Challa on August 12, 2020 at 5:37am

Storing energy in red bricks

Red bricks—some of the world's cheapest and most familiar building materials—can be converted into  storage units that can be charged to hold electricity, like a battery, according to new research

https://techxplore.com/news/2020-08-energy-red-bricks.html?utm_sour...

Comment by Dr. Krishna Kumari Challa on August 12, 2020 at 5:34am

Digital content on track to equal half Earth's mass by 2245

https://phys.org/news/2020-08-digital-content-track-equal-earth.htm...

Comment by Dr. Krishna Kumari Challa on August 11, 2020 at 7:19am

How Our Exhalations Help Spread Pathogens Such as SARS-CoV-2

Lydia Bourouiba, an expert in fluid dynamics and disease transmission at MIT, explains how the physics of sneezes and coughs leads to the spread of respiratory pathogens such as COVID-19.  

https://www.the-scientist.com/news-opinion/how-our-exhalations-help...

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Self-Experimentation in the Time of COVID-19: Scientists are taking their own vaccines

Confidence in their abilities? Or proving their trust-worthyness?

https://www.the-scientist.com/news-opinion/self-experimentation-in-...

Comment by Dr. Krishna Kumari Challa on August 11, 2020 at 6:19am

How pulse oxytometer works and how it discriminates ...

How a Popular Medical Device Encodes Racial Bias

Pulse oximeters give biased results for people with darker skin. The consequences could be serious.

To picture what’s happening inside a pulse ox—as health care providers call it—start by thinking about what’s happening inside your body. Blood saturated with oxygen is bright crimson thanks to iron-containing hemoglobin, which picks up the gas molecules from your lungs to deliver them to your organs. In the absence of oxygen, the same hemoglobin dims to a cold purple-red. The oximeter detects this chromatic chemistry by shining two lights—one infrared, one red—through your finger and sensing how much comes through on the other side. Oxygen-saturated hemoglobin absorbs more infrared light and also allows more red light to pass through than its deoxygenated counterpart. Adjusting for certain technicalities using your pulse, the device reads out the color of your blood several times a second.

To “see” your blood, though, the light must pass through your skin. This should give us pause, since a range of technologies based on color sensing are known to reproduce racial bias. Photographic film calibrated for white skin, for example, often created distorted images of nonwhite people until its built-in assumptions started to be acknowledged and reworked in the 1970s; traces of racial biases remain in photography still today. Similar disparities have surfaced around several health devices, including Fitbits. How had designers managed to avoid such problems in the case of the oximeter, I wondered? As I dug deeper, I couldn’t find any record that the problem ever was fully fixed. Most oximeters on the market today were initially calibrated primarily for light skin, and they still often reproduce subtle errors for nonwhite people.

https://bostonreview.net/science-nature-race/amy-moran-thomas-how-p...

Comment by Dr. Krishna Kumari Challa on August 11, 2020 at 6:07am

The Tragic Physics of the Deadly Explosion in Beirut 

A blast injury specialist explores the chemistry—and history—of explosions like the one captured in videos that swept across the world.
Comment by Dr. Krishna Kumari Challa on August 11, 2020 at 5:57am

Breakthrough technology purifies water using the power of sunlight

https://techxplore.com/news/2020-08-breakthrough-technology-purifie...

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Transgender and gender diverse people up to six times more likely to be autistic – new study

https://theconversation.com/transgender-and-gender-diverse-people-u...

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Heatwaves don’t just give you sunburn – they can harm your mental health too

https://theconversation.com/heatwaves-dont-just-give-you-sunburn-th...

Comment by Dr. Krishna Kumari Challa on August 11, 2020 at 5:44am

New treatment targets found for blinding retinal disease

When the eye isn't getting enough oxygen in the face of common conditions like premature birth or diabetes, it sets in motion a state of frenzied energy production that can ultimately result in blindness, and now scientists have identified new points where they may be able to calm the frenzy and instead enable recovery.  
In this high-energy environ, both the endothelial cells that will form new blood vessels in the retina—which could improve oxygen levels—and nearby microglia—a type of macrophage that typically keeps watch over the retina—prefer glycolysis as a means to turn glucose into their fuel.
 scientists have shown that in retinal disease, the excessive byproducts of this inefficient fuel production system initiate a crescendo of crosstalk between these two cell types. The talk promotes excessive inflammation and development of the classic mass of leaky, dysfunctional capillaries that can obstruct vision and lead to retinal detachment. 
The major byproduct of glycolysis is lactate, which also can be used as a fuel, for example, by our muscles in a strenuous workout. Microglia also need some lactate from the endothelial cells. But in disease, the lactate is in definite oversupply, which instead supports this destructive conversation between cells
This is a major problem : loss of vision because of compromised oxygen for a variety of reasons. This additional insight into how that process destroys vision, will enable us to find better ways to intervene.

In a low-oxygen environ, endothelial cells produce not only a lot of lactate, but also factors that encourage nearby microglia to be more active, and to use glycolysis to get more active.

In reality, microglia don't need the encouragement because they already also seem to prefer this method of energy production. But the extra lactate sent their way does spur them to produce even more energy and consequently even more lactate

The normally supportive immune cells also start overproducing inflammation-promoting factors like cytokines and growth factors that promote blood vessel growth or angiogenesis, which, in a vicious loop, further turns up glycolysis by the endothelial cells, which are now inclined to proliferate excessively.

"The reciprocal interaction between macrophages and (endothelial cells) promotes a feed-forward relationship that strongly augments angiogenesis," they write.

The destructive bottom line is termed pathological angiogenesis, a major cause of irreversible blindness in people of all ages, the scientists say, with problems like diabetic retinopathy, retinopathy of prematurity and age related macular degenration.

Our eyes clearly do not have sufficient oxygen, and they end up trying to generate more blood vesselsthrough this process called pathological angiogenesis, which is really hard to control.

Zhiping Liu et al. Glycolysis links reciprocal activation of myeloid cells and endothelial cells in the retinal angiogenic niche, Science Translational Medicine (2020). DOI: 10.1126/scitranslmed.aay1371

https://medicalxpress.com/news/2020-08-treatment-retinal-disease.ht...

Comment by Dr. Krishna Kumari Challa on August 11, 2020 at 5:36am

Medicine: 

Gulf War illness, chronic fatigue syndrome distinct illnesses, study suggests

https://medicalxpress.com/news/2020-08-gulf-war-illness-chronic-fat...

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How to get more cancer-fighting nanoparticles to where they are needed

https://phys.org/news/2020-08-cancer-fighting-nanoparticles.html?ut...

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Nanocatalysts that remotely control chemical reactions inside living cells

The enzymes responsible for catalytic reactions in our body's biological reactions are difficult to use for diagnosis or treatment as they react only to certain molecules or have low stability. Many researchers anticipate that if these issues are ameliorated or if artificial catalysts are developed to create a synergetic effect by meeting the enzymes in the body, there will be new ways to diagnose and treat diseases. In particular, if artificial catalysts that respond to external stimuli such as magnetic fields are developed, new treatment methods that remotely control bioreactions from outside the body can become a reality.

https://phys.org/news/2020-08-nanocatalysts-remotely-chemical-react...

 

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