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Comment by Dr. Krishna Kumari Challa on February 7, 2015 at 9:01am

Recent infections may curb risk of rheumatism
Recent gut and urinary tract infections may curb the risk of developing rheumatoid arthritis, suggests a new study from Karolinska Institutet published online in the journal Annals of the Rheumatic Diseases. According to the researchers, one possible explanation could lie in the way in which these infections alter the types of bacteria resident in the gut (microbiome).

The research team set out to look at the impact of different types of infection on the risk of developing rheumatoid arthritis in almost 6500 people living in south and central Sweden.
All participants were asked whether they had had any gut, urinary tract, or genital infections in the preceding two years. They were also asked if they had had prostatitis (inflamed prostate), or antibiotic treatment for sinusitis, tonsillitis/other throat infection, or pneumonia during this time.

Gut, urinary tract, and genital infections within the preceding two years were each associated with a significantly lowered risk of developing rheumatoid arthritis: 29 percent, 22 percent, and 20 percent, respectively. Further, having all three types of infection in the preceding two years was linked to a 50 percent lower risk, after taking account of influential factors.

By contrast, no such associations were found for recent respiratory infections and pneumonia. Factoring in smoking and socioeconomic background made no difference to the overall findings. However, since this is an observational study researchers point out that no definitive conclusions can be drawn about cause and effect.
Conclusions Gastrointestinal and urogenital infections, but not respiratory infections, are associated with a significantly lowered risk of RA. The results indicate that infections in general do not affect the risk for RA, but that certain infections, hypothetically associated with changes in the gut microbiome, could diminish the risk.
http://ard.bmj.com/content/early/2015/01/16/annrheumdis-2014-206493

Comment by Dr. Krishna Kumari Challa on February 7, 2015 at 8:57am

Psychobiotics: How gut bacteria mess with your mind

WE HAVE all experienced the influence of gut bacteria on our emotions. Just think how you felt the last time you had a stomach bug. Now it is becoming clear that certain gut bacteria can positively influence our mood and behaviour. The way they achieve this is gradually being uncovered, raising the possibility of unlocking new ways to treat neurobehavioural disorders such as depression and obsessive-compulsive disorder (OCD).

We acquire our intestinal microbes immediately after birth, and live in an important symbiotic relationship with them. There are far more bacteria in your gut than cells in your body, and their weight roughly equals that of your brain. These bacteria have a vast array of genes, capable of producing hundreds if not thousands of chemicals, many of which influence your brain.
http://www.newscientist.com/article/mg22129530.400-psychobiotics-ho...|NSNS|2015-0702-AUS-febemi2_apac|evergreen&utm_medium=EMP&utm_source=NSNS&utm_campaign=FebEMi2_APAC&utm_content=evergreen

Comment by Dr. Krishna Kumari Challa on February 7, 2015 at 8:35am

AVIAN INFLUENZA
Are Wild Birds to Blame?
Almost as soon as H5N1 avian influenza began its deadly sweep across Asia, people fingered migratory birds as likely culprits in its spread. Migrating birds offer an obvious way to connect the dots of H5N1 outbreaks along the east coast of Asia and, in just the past few months, its unexpected cross-continent jump to Siberia, Kazakhstan, and Turkey. Moreover, researchers have long known that these birds commonly harbor less virulent flu viruses, and many wild birds mingle with Asia's free-ranging domestic poultry, which have been decimated by H5N1.

But avian experts have been almost universally skeptical that wild birds are spreading the virus. One reason is that sampling of tens of thousands of birds has failed to turn up a single healthy wild bird carrying the pathogenic strain of H5N1, which has caused the death of more than 100 million domestic birds—and at least 60 humans—in Asia. Evidence so far suggests that H5N1 kills wild ducks and geese nearly as efficiently as it does chickens. “Dead ducks don't fly” has been the refrain, as avian experts point out that sick and dying birds simply can't spread viruses very far. Instead, epidemiologists investigating the virus's jump, even to geographically far-flung regions, keep turning up evidence suggesting that the poultry trade and other human activities are responsible.

Now, however, evidence implicating wild birds is starting to convince even some of the doubters. “Until about 2 months ago, I was pretty skeptical on whether wild birds were playing a role,” says David Suarez, a virologist with the U.S. Department of Agriculture's (USDA's) Southeast Poultry Research Laboratory in Athens, Georgia. “But now I feel that there is much stronger evidence that wild birds are spreading the virus.” What changed his mind, he says, was the death of 100 or so ducks, gulls, geese, and swans from H5N1 at a remote lake in Mongolia that he believes can't be explained by human activities. And, he and others add, in an unexpected twist, it's beginning to look as though the culprits might not be the long-suspected migratory waterfowl but another yet-unidentified wild species.

The implications are huge. If wild birds are carrying the disease, says Suarez, “it will be difficult or impossible to control the spread from country to country.” Nailing down the answer became even more urgent last week with the confirmation that H5N1 has now entered Europe.
http://www.sciencemag.org/content/310/5747/426.full?sid=2cf74c06-2d...

Comment by Dr. Krishna Kumari Challa on February 6, 2015 at 7:16am

A study, published in the journal Science recently, used a mathematical model to simulate the changes that take place during desertification and matched the theoretical results with real observations in termite-inhabited regions on the edge of deserts. And it was found that mounds of soil made by termites when they build their high-rise nests have been found to hold back the encroachment of deserts in dry, savannah grasslands threatened with desertification.
The ground surrounding termite mounds store nutrients and water better than it otherwise would, which allows plants to grow and flourish while the empty, termite-free land further away dries out, the researchers said.

A study discovered that the myriad of tiny underground tunnels created by termites when they build their multi-storey nests allow rainwater to penetrate the soil which helps to slow the spread of deserts in the dry grasslands of Africa, South America and Asia.

“The rain is the same everywhere, but because termites allow water to penetrate the soil better, the plants grow on or near the mounds as if there were more rain.
So, termites stop desertification! Termite mounds are a boon to ecology!

Comment by Dr. Krishna Kumari Challa on February 5, 2015 at 9:13am

Unconscious thought not so smart after all

Study on decision-making stokes controversy over power of distracted mind.
If you have to make a complex decision, will you do a better job if you absorb yourself in, say, a crossword puzzle instead of ruminating about your options? The idea that unconscious thought is sometimes more powerful than conscious thought is attractive, and echoes ideas popularized by books such as writer Malcolm Gladwell’s best-selling Blink.

Science pours in from Rosetta comet mission
GM microbes created that can’t escape the lab
Crunch time for pet theory on dark matter

But within the scientific community, ‘unconscious-thought advantage’ (UTA) has been controversial. Now Dutch psychologists have carried out the most rigorous study yet of UTA — and find no evidence for it.

Their conclusion, published this week in Judgement and Decision Making, is based on a large experiment that they designed to provide the best chance of capturing the effect should it exist, along with a sophisticated statistical analysis of previously published data.
http://www.nature.com/news/unconscious-thought-not-so-smart-after-a...

Comment by Dr. Krishna Kumari Challa on February 5, 2015 at 8:04am

Scientists unlock one of Nature’s best-kept secrets: How plants make natural medicines
Scientists at the John Innes Centre have discovered how plants make valuable natural products we rely on today for use as medicines, flavours and scents. This discovery has the potential to pave the way for the creation of entirely new drugs, flavourings and cosmetic ingredients.

Most plant-derived drugs, scents and flavours contain hydrocarbon rings in their structures – and until now exactly how Nature makes them has remained a mystery.

Recent work by a team of scientists at the John Innes Centre, led by Dr Paul O'Maille, resulted in the discovery of the origins of these cyclic or ring forming reactions in plants – which yield medicines like artemisinin: the most potent antimalarial drug, as well as flavours such as ginger and scents like bergamot.

The key to their success was breeding enzymes, the protein machinery that catalyses chemical reactions in plants. In particular they focused on enzymes that catalysed the formation of terpenes: the most diverse class of predominantly cyclic (ring-containing) natural products. By breeding a pair of enzymes, one that makes linear, less complex terpenes with one that makes cyclic terpenes, Dr Melissa Salmon, the lead author on the paper, was able to localize the trait of cyclization in the protein structure.
This research was published recently in Nature Communications.

Comment by Dr. Krishna Kumari Challa on February 5, 2015 at 6:50am

A team of researchers from MIT and the University of Liege, in Belgium, have shown through high-speed images of raindrops splashing down on leaves that raindrops can act as a dispersing agent of contaminated droplets from one plant to another.

Comment by Dr. Krishna Kumari Challa on February 4, 2015 at 9:43am

Mercury levels in Hawaiian Yellowfin tuna – known as ahi on the plate – are on the rise, scientists report February 2 in Environmental Toxicology and Chemistry.

Data collected in 1998 and 2008 showed that mercury levels increased at a rate of about 3.8 percent per year, the researchers say. A tuna about 75 kilograms in size might have had about 0.4 parts per million of mercury in its body in 1998. In 2008, the same-sized fish would have had around 0.6 parts per million.

The tuna’s increase in toxic baggage mirrors increasing levels of mercury pollution from human activities, such as burning coal in power plants and mining.
http://onlinelibrary.wiley.com/doi/10.1002/etc.2883/abstract

Comment by Dr. Krishna Kumari Challa on February 4, 2015 at 9:06am

Is there a The Best Position For Birth?
The time honored tradition of elevating women 15 degrees during birth does not actually reduce venous compression, study says.
New research is challenging what many obstetricians and physician anesthesiologists believe is the best way to position women during labor. According to a study published in Anesthesiology, the traditional practice of positioning women on their side does not effectively reduce compression of the inferior vena cava, a large vein located near the abdominal area that returns blood to the heart, as previously thought. "It is widely believed that lying women flat on their back during labor can lead to dangerously low blood pressure caused by the compression of both the inferior vena cava and the aorta due to the weight of the fetus," said Dr. Hideyuki Higuchi, study author from Tokyo Women's Medical University. "It is accepted by many physicians that positioning women on their side, with hips tilted at 15 degrees, during childbirth reduces this complication. However, our research found no evidence of aortic compression in pregnant women in any position and the recommended degree of tilt that most physicians follow did not reduce compression of the inferior vena cava at all. This is the first study to challenge this antiquated practice." In the study, magnetic resonance images (MRI) of ten pregnant women at full term and ten non-pregnant women were obtained for measurement of the abdominal aorta, the largest artery in the abdominal cavity, and the inferior vena cava. Measurements were taken while the women laid flat on their back and while tilted at 15, 30, and 45 degrees. Foam was placed under the right side of the study participants to achieve the desired amount of tilt. The study found that abdominal aortic blood volume did not differ significantly between pregnant and non-pregnant women regardless of the position in which they were placed. Conversely, inferior vena cava blood volume was significantly lower in pregnant women than in non-pregnant women when the women were positioned flat on their back, indicating almost complete compression of the vein. Inferior vena cava blood volume did not increase at 15 degrees, but partially increased at 30 degrees. An accompanying editorial commented favorably on the study's results, but offered a word of caution: "Although it would be great to be able to conclude by saying all of our patients in the delivery room should be placed in at least 30 degrees left lateral tilt after regional anesthetic, I have serious doubts that our obstetric colleagues would find it a reasonable position for cesarean delivery, particularly in obese patients," said editorial author Dr. Craig Palmer from the University of Arizona College of Medicine. "There quite probably are patients for whom the modest (15 degree) tilt we apply has a salutary effect. However, I will have to be less dogmatic about the practice. Kudos to the authors of this study for revisiting an 'ancient' practice, applying current technology to the matter, and shedding new light on an old routine." The article can be found at: Higuchi et al. (2015) Effect of Lateral Tilt Angle on the Volume of the Abdominal Aorta and Inferior Vena Cava in Pregnant and Nonpregnant Women Determined by Magnetic Resonance Imaging.
Source: American Society of Anesthesiologists.

Comment by Dr. Krishna Kumari Challa on February 4, 2015 at 8:39am

Gravitational waves discovery now officially dead

Combined data from South Pole experiment BICEP2 and Planck probe point to Galactic dust as confounding signal.
A team of astronomers that last year reported evidence for gravitational waves from the early Universe has now withdrawn the claim. A joint analysis of data recorded by the team's BICEP2 telescope at the South Pole and by the European spacecraft Planck has revealed that the signal can be entirely attributed to dust in the Milky Way rather than having a more ancient, cosmic origin.

The European Space Agency (ESA) announced the long-awaited results on January 30, a day after a summary of it had been unintentionally posted online by French members of the Planck satellite team and then widely circulated before it was taken down.
http://www.nature.com/news/gravitational-waves-discovery-now-offici...

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