Science, Art, Litt, Science based Art & Science Communication
JAI VIGNAN
All about Science - to remove misconceptions and encourage scientific temper
Communicating science to the common people
'To make them see the world differently through the beautiful lense of science'
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Latest Activity: 3 hours ago
WE LOVE SCIENCE HERE BECAUSE IT IS A MANY SPLENDOURED THING
THIS IS A WAR ZONE WHERE SCIENCE FIGHTS WITH NONSENSE AND WINS
“The greatest enemy of knowledge is not ignorance, it is the illusion of knowledge.”
"Being a scientist is a state of mind, not a profession!"
"Science, when it's done right, can yield amazing things".
The Reach of Scientific Research From Labs to Laymen
The aim of science is not only to open a door to infinite knowledge and wisdom but to set a limit to infinite error.
"Knowledge is a Superpower but the irony is you cannot get enough of it with ever increasing data base unless you try to keep up with it constantly and in the right way!" The best education comes from learning from people who know what they are exactly talking about.
Science is this glorious adventure into the unknown, the opportunity to discover things that nobody knew before. And that’s just an experience that’s not to be missed. But it’s also a motivated effort to try to help humankind. And maybe that’s just by increasing human knowledge—because that’s a way to make us a nobler species.
If you are scientifically literate the world looks very different to you.
We do science and science communication not because they are easy but because they are difficult!
“Science is not a subject you studied in school. It’s life. We 're brought into existence by it!"
Links to some important articles :
1. Interactive science series...
a. how-to-do-research-and-write-research-papers-part 13
b. Some Qs people asked me on science and my replies to them...
Part 6, part-10, part-11, part-12, part 14 , part- 8,
part- 1, part-2, part-4, part-5, part-16, part-17, part-18 , part-19 , part-20
part-21 , part-22, part-23, part-24, part-25, part-26, part-27 , part-28
part-29, part-30, part-31, part-32, part-33, part-34, part-35, part-36, part-37,
part-38, part-40, part-41, part-42, part-43, part-44, part-45, part-46, part-47
Part 48, part49, Critical thinking -part 50 , part -51, part-52, part-53
part-54, part-55, part-57, part-58, part-59, part-60, part-61, part-62, part-63
part 64, part-65, part-66, part-67, part-68, part 69, part-70 part-71, part-73 ...
.......306
BP variations during pregnancy part-72
who is responsible for the gender of their children - a man or a woman -part-56
c. some-questions-people-asked-me-on-science-based-on-my-art-and-poems -part-7
d. science-s-rules-are-unyielding-they-will-not-be-bent-for-anybody-part-3-
e. debate-between-scientists-and-people-who-practice-and-propagate-pseudo-science - part -9
f. why astrology is pseudo-science part 15
g. How Science is demolishing patriarchal ideas - part-39
2. in-defence-of-mangalyaan-why-even-developing-countries-like-india need space research programmes
3. Science communication series:
a. science-communication - part 1
b. how-scienitsts-should-communicate-with-laymen - part 2
c. main-challenges-of-science-communication-and-how-to-overcome-them - part 3
d. the-importance-of-science-communication-through-art- part 4
e. why-science-communication-is-geting worse - part 5
f. why-science-journalism-is-not-taken-seriously-in-this-part-of-the-world - part 6
g. blogs-the-best-bet-to-communicate-science-by-scientists- part 7
h. why-it-is-difficult-for-scientists-to-debate-controversial-issues - part 8
i. science-writers-and-communicators-where-are-you - part 9
j. shooting-the-messengers-for-a-different-reason-for-conveying-the- part 10
k. why-is-science-journalism-different-from-other-forms-of-journalism - part 11
l. golden-rules-of-science-communication- Part 12
m. science-writers-should-develop-a-broader-view-to-put-things-in-th - part 13
n. an-informed-patient-is-the-most-cooperative-one -part 14
o. the-risks-scientists-will-have-to-face-while-communicating-science - part 15
p. the-most-difficult-part-of-science-communication - part 16
q. clarity-on-who-you-are-writing-for-is-important-before-sitting-to write a science story - part 17
r. science-communicators-get-thick-skinned-to-communicate-science-without-any-bias - part 18
s. is-post-truth-another-name-for-science-communication-failure?
t. why-is-it-difficult-for-scientists-to-have-high-eqs
u. art-and-literature-as-effective-aids-in-science-communication-and teaching
v.* some-qs-people-asked-me-on-science communication-and-my-replies-to-them
** qs-people-asked-me-on-science-and-my-replies-to-them-part-173
w. why-motivated-perception-influences-your-understanding-of-science
x. science-communication-in-uncertain-times
y. sci-com: why-keep-a-dog-and-bark-yourself
z. How to deal with sci com dilemmas?
A+. sci-com-what-makes-a-story-news-worthy-in-science
B+. is-a-perfect-language-important-in-writing-science-stories
C+. sci-com-how-much-entertainment-is-too-much-while-communicating-sc
D+. sci-com-why-can-t-everybody-understand-science-in-the-same-way
E+. how-to-successfully-negotiate-the-science-communication-maze
4. Health related topics:
a. why-antibiotic-resistance-is-increasing-and-how-scientists-are-tr
b. what-might-happen-when-you-take-lots-of-medicines
c. know-your-cesarean-facts-ladies
d. right-facts-about-menstruation
e. answer-to-the-question-why-on-big-c
f. how-scientists-are-identifying-new-preventive-measures-and-cures-
g. what-if-little-creatures-high-jack-your-brain-and-try-to-control-
h. who-knows-better?
k. can-rust-from-old-drinking-water-pipes-cause-health-problems
l. pvc-and-cpvc-pipes-should-not-be-used-for-drinking-water-supply
m. melioidosis
o. desensitization-and-transplant-success-story
p. do-you-think-the-medicines-you-are-taking-are-perfectly-alright-then revisit your position!
q. swine-flu-the-difficlulties-we-still-face-while-tackling-the-outb
r. dump-this-useless-information-into-a-garbage-bin-if-you-really-care about evidence based medicine
s. don-t-ignore-these-head-injuries
u. allergic- agony-caused-by-caterpillars-and-moths
General science:
a.why-do-water-bodies-suddenly-change-colour
b. don-t-knock-down-your-own-life-line
c. the-most-menacing-animal-in-the-world
d. how-exo-planets-are-detected
e. the-importance-of-earth-s-magnetic-field
f. saving-tigers-from-extinction-is-still-a-travail
g. the-importance-of-snakes-in-our-eco-systems
h. understanding-reverse-osmosis
i. the-importance-of-microbiomes
j. crispr-cas9-gene-editing-technique-a-boon-to-fixing-defective-gen
k. biomimicry-a-solution-to-some-of-our-problems
5. the-dilemmas-scientists-face
6. why-we-get-contradictory-reports-in-science
7. be-alert-pseudo-science-and-anti-science-are-on-prowl
8. science-will-answer-your-questions-and-solve-your-problems
9. how-science-debunks-baseless-beliefs
10. climate-science-and-its-relevance
11. the-road-to-a-healthy-life
12. relative-truth-about-gm-crops-and-foods
13. intuition-based-work-is-bad-science
14. how-science-explains-near-death-experiences
15. just-studies-are-different-from-thorough-scientific-research
16. lab-scientists-versus-internet-scientists
17. can-you-challenge-science?
18. the-myth-of-ritual-working
19.science-and-superstitions-how-rational-thinking-can-make-you-work-better
20. comets-are-not-harmful-or-bad-omens-so-enjoy-the-clestial-shows
21. explanation-of-mysterious-lights-during-earthquakes
22. science-can-tell-what-constitutes-the-beauty-of-a-rose
23. what-lessons-can-science-learn-from-tragedies-like-these
24. the-specific-traits-of-a-scientific-mind
25. science-and-the-paranormal
26. are-these-inventions-and-discoveries-really-accidental-and-intuitive like the journalists say?
27. how-the-brain-of-a-polymath-copes-with-all-the-things-it-does
28. how-to-make-scientific-research-in-india-a-success-story
29. getting-rid-of-plastic-the-natural-way
30. why-some-interesting-things-happen-in-nature
31. real-life-stories-that-proves-how-science-helps-you
32. Science and trust series:
a. how-to-trust-science-stories-a-guide-for-common-man
b. trust-in-science-what-makes-people-waver
c. standing-up-for-science-showing-reasons-why-science-should-be-trusted
You will find the entire list of discussions here: http://kkartlab.in/group/some-science/forum
( Please go through the comments section below to find scientific research reports posted on a daily basis and watch videos based on science)
Get interactive...
Please contact us if you want us to add any information or scientific explanation on any topic that interests you. We will try our level best to give you the right information.
Our mail ID: kkartlabin@gmail.com
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Scientists solve a 100-year-old mystery about cancer
In 1921, German physician Otto Warburg observed that cancer cells harvest energy from glucose sugar in a strangely inefficient manner: rather than "burn" it using oxygen, cancer cells do what yeast do—they ferment it. This oxygen-independent process occurs quickly, but leaves much of the energy in glucose untapped.
Various hypotheses to explain the Warburg effect have been proposed over the years, including the idea that cancer cells have defective mitochondria—their "energy factories"—and therefore cannot perform the controlled burning of glucose. But none of these explanations has withstood the test of time. (Cancer cells' mitochondria work just fine, for example.)
Now a research team offers a new answer, based on a hefty set of genetic and biochemical experiments and published January 21 in the journal Science.It comes down to a previously unappreciated link between Warburg metabolism and the activity of a powerhouse enzyme in the cell called PI3 kinase. PI3 kinase is a key signaling molecule that functions almost like a commander-in-chief of cell metabolism. Most of the energy-costly cellular events in cells, including cell division, occur only when PI3 kinase gives the cue. As cells shift to Warburg metabolism, the activity of PI3 kinase is increased, and in turn, the cells' commitment to divide is strengthened. It's a bit like giving the commander-in-chief a megaphone.The findings revise the commonly accepted view among biochemists that sees metabolism as secondary to cell signaling. They also suggest that targeting metabolism could be an effective way to thwart cancer growth.
As with immune cells, cancer cells may employ Warburg metabolism as a way to sustain the activity of this signaling pathway and therefore ensure their continued growth and division.
The results raise the intriguing possibility that doctors could curb cancer growth by blocking the activity of LDHA—the Warburg "switch."
Ke Xu et al, Glycolysis fuels phosphoinositide 3-kinase signaling to bolster T cell immunity, Science (2021). DOI: 10.1126/science.abb2683
https://medicalxpress.com/news/2021-01-scientists-year-old-mystery-...
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S. Africa virus strain poses 're-infection risk': study
The coronavirus variant detected in South Africa poses a "significant re-infection risk" and raises concerns over vaccine effectiveness, according to preliminary research Wednesday, as separate studies suggested the British strain would likely be constrained by immunisations. Several new variants -- each with a cluster of genetic mutations -- have emerged in recent weeks, sparking fears over an increase in infectiousness as well as suggestions that the virus could begin to elude immune response, whether from prior infection or a vaccine. These new variants, detected from Britain, South Africa and Brazil, have mutations to the virus' spike protein, which enables the virus to latch onto human cells and therefore plays a key role in driving infections. But it is one mutation in particular -- known as E484K and present in the variants detected in South Africa and Brazil but not the one from Britain -- that has experts particularly worried about immunity "escape".
They found that it was resistant to neutralising antibodies built up from prior infection, but said more research was needed into the effectiveness of other parts of the immune response.
The 501Y.V2 lineage, which contains nine spike mutations and rapidly emerged in South Africa during the second half of 2020, is largely resistant to neutralising antibodies elicited by infection with previously circulating lineages. This suggests that, despite the many people who have already been infected with SARS-CoV-2 globally and are presumed to have accumulated some level of immunity, new variants such as 501Y.V2 pose a significant re-infection risk.
The researchers added that this might also affect the use of convalescent plasma as a treatment for Covid-19. They also suggested it could have "implications" for vaccines developed based on immune responses to the virus's spike protein.
https://researchnews.cc/news/4730/S--Africa-virus-strain-poses--re-...
Sci-COM : Storytelling can be a powerful tool for science
Credible science communication and storytelling are not mutually exclusive — they can be great allies.
In contrast with straight communication of experimental results, telling individual research stories portrays science as a human-driven endeavour, full of successes, uncertainties, missteps and failures, which in turn promotes transparency. What really matters is what story is being told and by whom.
https://www.nature.com/articles/d41586-021-00108-w?utm_source=Natur...
Bubble micro-robots!
Prostate cancer is one of the most common cancers among men. Patients are determined to have prostate cancer primarily based on PSA, a cancer factor in blood. However, as diagnostic accuracy is as low as 30%, a considerable number of patients undergo additional invasive biopsy and thus suffer from resultant side effects, such as bleeding and pain.
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A new technique allowed researchers to observe in greater detail how heat alters keratin proteins, helping in their search for ingredients that can prevent heat-damaged hair.
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Scottish bacteriologist Alexander Fleming's discovery of penicillin, the world's first antibiotic, saved countless lives. But even as the bacteria killer first hit the U.S. market—in the closing months of World War II—Fleming warned the world about what penicillin might unleash.
Pathogenic bacteria in humans are developing resistance to antibiotics much faster than expected. Now, computational research shows that one reason could be significant genetic transfer between bacteria in our ecosystems and to humans. This work has also led to new tools for resistance researchers.
Completely different species of bacteria can spread resistance genes to each other through plasmids—small DNA molecules where bacteria store some of their genes outside the chromosome. When two bacterial cells come into contact, they can copy plasmids to each other. This is called conjugation, and it is the most important mechanism for spreading antibiotic resistance.
In recent years, we've seen that resistance genes spread to human pathogens to a much greater degree than anyone expected.
Many of the genes appear to have originated in a wide array of bacterial species and environments, such as soil, water and plant bacteria. This has been difficult to explain, because although conjugation is very common, we've thought that there was a distinct limitation for which bacterial species can transfer plasmids to each other. Plasmids belong to different mobility groups, or MOB groups, so they can't transfer between just any bacterial species.
The results show, among other things, that:
The last part means that there may be transfer mechanisms between large numbers of bacterial species and environments where we previously believed there were barriers.
Jan Zrimec, Multiple plasmid origin‐of‐transfer regions might aid the spread of antimicrobial resistance to human pathogens, MicrobiologyOpen (2020). DOI: 10.1002/mbo3.1129
https://phys.org/news/2021-01-antibiotic-resistance-easily.html?utm...
Scientists are reporting troubling signs that some recent mutations of the virus that causes COVID-19 may modestly curb the effectiveness of two current vaccines, although they stress that the shots still protect against the disease.
Researchers expressed concern Wednesday about the preliminary findings, in large part because they suggest that future mutations could undermine vaccines.
A different, more limited study out Wednesday gave encouraging news about one vaccine's protection against some of the mutations.
One way vaccines work is to prompt the immune system to make antibodies that block the virus from infecting cells. The Rockefeller researchers got blood samples from 20 people who had received either the Moderna or Pfizer vaccine and tested their antibodies against various virus mutations in the lab.
With some, the antibodies didn't work as well against the virus—activity was one-to-threefold less, depending on the mutation. It's a small difference but it is definitely a difference. The antibody response is "not as good" at blocking the virus.
Earlier research established that the two vaccines are about 95% effective in preventing COVID-19 illness.
The latest findings were posted late Tuesday on an online website for researchers.
We don't want people thinking that the current vaccine is already outdated. That's absolutely not true. There's still immunity here ... a good level of protection but the mutations "do in fact reduce how well our immune response is recognizing the virus."
We've got an arms race between the vaccines and the virus. The slower we roll out vaccine around the world, the more opportunities we give this virus to escape" and develop mutations
https://www.biorxiv.org/content/10.1101/2021.01.15.426911v1
https://medicalxpress.com/news/2021-01-covid-mutations-dampen-vacci...
Scientists are reporting troubling signs that some recent mutations of the virus that causes COVID-19 may modestly curb the effectiveness of two current vaccines, although they stress that the shots still protect against the disease.
Researchers expressed concern Wednesday about the preliminary findings, in large part because they suggest that future mutations could undermine vaccines. The research tested coronaviruses from the United Kingdom, South Africa and Brazil, and was led by Rockefeller University in New York with scientists from the National Institutes of Health and elsewhere.
A different, more limited study out Wednesday gave encouraging news about one vaccine's protection against some of the mutations.
One way vaccines work is to prompt the immune system to make antibodies that block the virus from infecting cells. The Rockefeller researchers got blood samples from 20 people who had received either the Moderna or Pfizer vaccine and tested their antibodies against various virus mutations in the lab.
With some, the antibodies didn't work as well against the virus—activity was one-to-threefold less, depending on the mutation.
It's a small difference but it is definitely a difference. The antibody response is "not as good" at blocking the virus.
Earlier research established that the two vaccines are about 95% effective in preventing COVID-19 illness.
The latest findings were posted late Tuesday on an online website for researchers
https://medicalxpress.com/news/2021-01-covid-mutations-dampen-vacci...
Attine ants are farmers, and they grow fungus as food. Pseudonocardia and Streptomyces bacteria are their farmhands, producing metabolites that protect the crop from pathogens. Surprisingly, these metabolites lack common structural features across bacteria from different geographic locations, even though the ants share a common ancestor. Now, researchers report in ACS Central Science they have identified the first shared antifungal compound among many of these bacteria across Brazil. The compound could someday have medical applications.
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Warnings about misinformation are now regularly posted on Twitter, Facebook, and other social media platforms, but not all of these cautions are created equal. New research from Rensselaer Polytechnic Institute shows that artificial intelligence can help form accurate news assessments—but only when a news story is first emerging.
We know that there are many things left to discover, such as blue jets, elves and red sprites. These bizarre-sounding things are very difficult to observe from the surface of the Earth. As a new Nature paper reports, however, the European Atmosphere-Space Interactions Monitor (ASIM) observatory on the International Space Station is helping scientists find answers.
Looking down on Earth's weather from the International Space Station 400 km above, ASIM's enhanced perspective is shedding new light on weather phenomena and their characteristics.
The collection of optical cameras, photometers and an X- and gamma-ray detector was installed on the Space Station in 2018. It is designed to look for electrical discharges originating in stormy weather conditions that extend above thunderstorms into the upper atmosphere.
And now, for the first time for an ESA International Space Station experiment, ASIM's findings have been published in Nature as front-page article. The paper describes a sighting of five intense blue flashes in a cloud top, one generating a 'blue jet' into the stratosphere.
A blue jet is a form of lightning that shoots upwards from thunderstorm clouds. They can reach as far 50 km into the stratosphere and last less than a second. The space storm-hunter measured a blue jet that was kicked off with and intense five 10-microsecond flash in a cloud near the island of Naru in the Pacific Ocean.
The flash also generated equally fantastic-sounding 'elves'. Elves are rapidly expanding rings of optical and UV emissions at the bottom of the ionosphere. Here, electrons, radio waves and the atmosphere interact to form these emissions.
Capturing these phenomena using ASIM's highly sensitive tools is vital for scientists researching weather systems on Earth.
Observation of the onset of a blue jet into the stratosphere, Nature (2021). DOI: 10.1038/s41586-020-03122-6 , www.nature.com/articles/s41586-020-03122-6
https://phys.org/news/2021-01-genesis-blue-lightning-stratosphere-i...
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