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JAI VIGNAN

All about Science - to remove misconceptions and encourage scientific temper

Communicating science to the common people

'To make them see the world differently through the beautiful lense of science'

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WE LOVE SCIENCE HERE BECAUSE IT IS A MANY SPLENDOURED THING

THIS IS A WAR ZONE WHERE SCIENCE FIGHTS WITH NONSENSE AND WINS

“The greatest enemy of knowledge is not ignorance, it is the illusion of knowledge.”

"Being a scientist is a state of mind, not a profession!"

"Science, when it's done right, can yield amazing things".

The Reach of Scientific Research From Labs to Laymen

The aim of science is not only to open a door to infinite knowledge and wisdom but to set a limit to infinite error.

"Knowledge is a Superpower but the irony is you cannot get enough of it with ever increasing data base unless you try to keep up with it constantly and in the right way!" The best education comes from learning from people who know what they are exactly talking about.

Science is this glorious adventure into the unknown, the opportunity to discover things that nobody knew before. And that’s just an experience that’s not to be missed. But it’s also a motivated effort to try to help humankind. And maybe that’s just by increasing human knowledge—because that’s a way to make us a nobler species.

If you are scientifically literate the world looks very different to you.

We do science and science communication not because they are easy but because they are difficult!

“Science is not a subject you studied in school. It’s life. We 're brought into existence by it!"

Links to some important articles :

1. Interactive science series...

a. how-to-do-research-and-write-research-papers-part 13

b. Some Qs people asked me on science and my replies to them...

Part 6, part-10, part-11, part-12, part 14 , part- 8,

part- 1, part-2, part-4, part-5, part-16, part-17, part-18 , part-19 , part-20

part-21 , part-22, part-23, part-24, part-25, part-26, part-27 , part-28

part-29, part-30, part-31, part-32, part-33, part-34, part-35, part-36, part-37,

part-38, part-40, part-41, part-42, part-43, part-44, part-45, part-46, part-47

Part 48, part49, Critical thinking -part 50 , part -51, part-52, part-53

part-54, part-55, part-57, part-58, part-59, part-60, part-61, part-62, part-63

part 64, part-65, part-66, part-67, part-68, part 69, part-70 part-71, part-73 ...

.......306

BP variations during pregnancy part-72

who is responsible for the gender of their children - a man or a woman -part-56

c. some-questions-people-asked-me-on-science-based-on-my-art-and-poems -part-7

d. science-s-rules-are-unyielding-they-will-not-be-bent-for-anybody-part-3-

e. debate-between-scientists-and-people-who-practice-and-propagate-pseudo-science - part -9

f. why astrology is pseudo-science part 15

g. How Science is demolishing patriarchal ideas - part-39

2. in-defence-of-mangalyaan-why-even-developing-countries-like-india need space research programmes

3. Science communication series:

a. science-communication - part 1

b. how-scienitsts-should-communicate-with-laymen - part 2

c. main-challenges-of-science-communication-and-how-to-overcome-them - part 3

d. the-importance-of-science-communication-through-art- part 4

e. why-science-communication-is-geting worse - part 5

f. why-science-journalism-is-not-taken-seriously-in-this-part-of-the-world - part 6

g. blogs-the-best-bet-to-communicate-science-by-scientists- part 7

h. why-it-is-difficult-for-scientists-to-debate-controversial-issues - part 8

i. science-writers-and-communicators-where-are-you - part 9

j. shooting-the-messengers-for-a-different-reason-for-conveying-the- part 10

k. why-is-science-journalism-different-from-other-forms-of-journalism - part 11

l. golden-rules-of-science-communication- Part 12

m. science-writers-should-develop-a-broader-view-to-put-things-in-th - part 13

n. an-informed-patient-is-the-most-cooperative-one -part 14

o. the-risks-scientists-will-have-to-face-while-communicating-science - part 15

p. the-most-difficult-part-of-science-communication - part 16

q. clarity-on-who-you-are-writing-for-is-important-before-sitting-to write a science story - part 17

r. science-communicators-get-thick-skinned-to-communicate-science-wi thout-any-bias - part 18

s. is-post-truth-another-name-for-science-communication-failure?

t. why-is-it-difficult-for-scientists-to-have-high-eqs

u. art-and-literature-as-effective-aids-in-science-communication-and teaching

v.* some-qs-people-asked-me-on-science communication-and-my-replies-to-them

** qs-people-asked-me-on-science-and-my-replies-to-them-part-173

w. why-motivated-perception-influences-your-understanding-of-science

x. science-communication-in-uncertain-times

y. sci-com: why-keep-a-dog-and-bark-yourself

z. How to deal with sci com dilemmas?

A+. sci-com-what-makes-a-story-news-worthy-in-science

B+. is-a-perfect-language-important-in-writing-science-stories

C+. sci-com-how-much-entertainment-is-too-much-while-communicating-sc

D+. sci-com-why-can-t-everybody-understand-science-in-the-same-way

E+. how-to-successfully-negotiate-the-science-communication-maze

4. Health related topics:

a. why-antibiotic-resistance-is-increasing-and-how-scientists-are-tr

b. what-might-happen-when-you-take-lots-of-medicines

c. know-your-cesarean-facts-ladies

d. right-facts-about-menstruation

e. answer-to-the-question-why-on-big-c

f. how-scientists-are-identifying-new-preventive-measures-and-cures-

g. what-if-little-creatures-high-jack-your-brain-and-try-to-control-

h. who-knows-better?

i. mycotoxicoses

j. immunotherapy

k. can-rust-from-old-drinking-water-pipes-cause-health-problems

l. pvc-and-cpvc-pipes-should-not-be-used-for-drinking-water-supply

m. melioidosis

n.vaccine-woes

o. desensitization-and-transplant-success-story

p. do-you-think-the-medicines-you-are-taking-are-perfectly-alright-then revisit your position!

q. swine-flu-the-difficlulties-we-still-face-while-tackling-the-outb

r. dump-this-useless-information-into-a-garbage-bin-if-you-really-ca re about evidence based medicine

s. don-t-ignore-these-head-injuries

t. the-detoxification-scam

u. allergic- agony-caused-by-caterpillars-and-moths

General science:

a.why-do-water-bodies-suddenly-change-colour

b. don-t-knock-down-your-own-life-line

c. the-most-menacing-animal-in-the-world

d. how-exo-planets-are-detected

e. the-importance-of-earth-s-magnetic-field

f. saving-tigers-from-extinction-is-still-a-travail

g. the-importance-of-snakes-in-our-eco-systems

h. understanding-reverse-osmosis

i. the-importance-of-microbiomes

j. crispr-cas9-gene-editing-technique-a-boon-to-fixing-defective-gen

k. biomimicry-a-solution-to-some-of-our-problems

5. the-dilemmas-scientists-face

6. why-we-get-contradictory-reports-in-science

7. be-alert-pseudo-science-and-anti-science-are-on-prowl

8. science-will-answer-your-questions-and-solve-your-problems

9. how-science-debunks-baseless-beliefs

10. climate-science-and-its-relevance

11. the-road-to-a-healthy-life

12. relative-truth-about-gm-crops-and-foods

13. intuition-based-work-is-bad-science

14. how-science-explains-near-death-experiences

15. just-studies-are-different-from-thorough-scientific-research

16. lab-scientists-versus-internet-scientists

17. can-you-challenge-science?

18. the-myth-of-ritual-working

19.science-and-superstitions-how-rational-thinking-can-make-you-work -better

20. comets-are-not-harmful-or-bad-omens-so-enjoy-the-clestial-shows

21. explanation-of-mysterious-lights-during-earthquakes

22. science-can-tell-what-constitutes-the-beauty-of-a-rose

23. what-lessons-can-science-learn-from-tragedies-like-these

24. the-specific-traits-of-a-scientific-mind

25. science-and-the-paranormal

26. are-these-inventions-and-discoveries-really-accidental-and-intuitive like the journalists say?

27. how-the-brain-of-a-polymath-copes-with-all-the-things-it-does

28. how-to-make-scientific-research-in-india-a-success-story

29. getting-rid-of-plastic-the-natural-way

30. why-some-interesting-things-happen-in-nature

31. real-life-stories-that-proves-how-science-helps-you

32. Science and trust series:

a. how-to-trust-science-stories-a-guide-for-common-man

b. trust-in-science-what-makes-people-waver

c. standing-up-for-science-showing-reasons-why-science-should-be-trusted

You will find the entire list of discussions here: http://kkartlab.in/group/some-science/forum

( Please go through the comments section below to find scientific research reports posted on a daily basis and watch videos based on science)

Get interactive...

Please contact us if you want us to add any information or scientific explanation on any topic that interests you. We will try our level best to give you the right information.

Our mail ID: kkartlabin@gmail.com

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Comment by Dr. Krishna Kumari Challa on December 30, 2020 at 9:29am: **Using wood to build satellites

Japanese company Sumitomo Forestry has announced a joint development project with Kyoto University to test the idea of using wood as a component in satellite construction. As part of the announcement, officials with Sumitomo Forestry told reporters that work on the project will begin with experiments designed to test different types of wood in extreme environments.

Some of the major components in most satellites include aluminum, Kevlar and aluminum alloys, which are able to withstand both temperature extremes and constant bombardment by radiation—all in a vacuum. Unfortunately, these characteristics also allow satellites to remain in orbit long after their usefulness has ended, resulting in constant additions to the space junk orbiting the planet.

https://techxplore.com/news/2020-12-japanese-pairing-wood-satellite...

Comment by Dr. Krishna Kumari Challa on December 30, 2020 at 8:25am: Did you know that in 1110, the Moon Vanished from our view. Here are the answers to the Q why:

We know this event happened because researchers have drilled and analysed ice cores - samples taken from deep within ice sheets or glaciers, which have trapped sulphur aerosols produced by volcanic eruptions reaching the stratosphere and settling back on the surface.

Ice can thus preserve evidence of volcanism over incredibly long timescales, but pinpointing the precise date of an event that shows up in the layers of an ice core is still tricky business.

In this case, scientists had assumed the sulphurous deposit was left by a major eruption unleashed in 1104 by Iceland's Hekla, a volcano sometimes called the 'Gateway to Hell'. Since the thin strip of ice ranks among the largest sulfate deposition signals of the last millennium, it sounds plausible.

All the evidence, taken together, suggests a 'forgotten' cluster of volcanic eruptions in 1108 to 1110 unleashed terrible consequences on humanity. We're only rediscovering them now.

https://www.nature.com/articles/s41598-020-63339-3

https://www.sciencealert.com/in-1110-the-moon-vanished-from-the-sky...

Comment by Dr. Krishna Kumari Challa on December 30, 2020 at 6:50am: Albert Einstein's brain was removed within seven and a half hours of his death. His brain has attracted attention because of his supposed reputation as one of the foremost geniuses of the 20th century.
Einstein's autopsy was conducted in the lab of Thomas Stoltz Harvey. The story is interesting. Einstein did not want his brain or body to be studied. Harvey took the brain anyway, without permission from Einstein or his family, dissected and studied it.
Although several things were attributed to his brain structure, experts say these studies are flawed. Because all human brains are unique and different from others in some ways. Therefore, assuming unique features in Einstein's brain were connected with his genius goes beyond the evidence. Moreover, correlating unusual brain features with any characteristic requires studying many brains with those features, and scanning the brains of many very capable scientists would be better research than investigating the brains of just one or two geniuses.

So we don't give much importance to any of the things mentioned about Einstein's brain. Flawed research doesn't need our attention.

The strange afterlife of Einstein's brain

Comment by Dr. Krishna Kumari Challa on December 29, 2020 at 12:49pm: Anti-counterfeiting tech by NUS researchers does reliable AI authentication under extreme conditions

Comment by Dr. Krishna Kumari Challa on December 29, 2020 at 11:02am: German care home workers accidentally given five times covid vaccine dose

Eight care home workers in Germany were accidentally injected with five doses of the COVID-19 vaccine, local authorities said Monday—but are suffering no serious ill effects so far.

https://medicalxpress.com/news/2020-12-german-home-workers-vaccine-...

https://www.thelocal.de/20201228/german-care-home-workers-accidenta...

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The triumph of science

Number of americans willing to get COVID-19 vaccine continues to rise

When queried in polls conducted earlier this year, only about half of American adults said they planned to get any vaccine against the new coronavirus. But after a largely successful rollout this month of two safe and effective shots, many of those initial doubters now say they'll line up to get their vaccine doses when their turn comes.

Vaccine polls earlier showed vaccine acceptance rates rising from about 50% this summer to more than 60% and, in one poll, 73%. Resistance is fading slowly among most groups.

That last number approaches the threshold scientists have deemed necessary for herd immunity, where enough of a population is immune and the spread of the coronavirus begins to recede.

This change is due to the fantastic stats associated with the vaccines, according to skeptics. Media campaigns, including on-camera moments with politicians and scientists—such as Vice President Mike Pence, President-Elect Joe Biden and Dr. Anthony Fauci—all rolling up their sleeves for the shots may have also helped boost acceptance.

People say ... "the news that it was 95% effective sold me". The side effects sound like what you get after a bad night of drinking and you hurt the next day. Well, we've had many of those and can deal with that to get rid of the face masks and covid infection nightmare.

https://medicalxpress.com/news/2020-12-americans-covid-vaccine-1.ht...

Comment by Dr. Krishna Kumari Challa on December 29, 2020 at 9:11am: Gut cells sound the alarm when parasites invade

To effectively combat an infection, the body first has to sense it's been invaded, then the affected tissue must send out signals to corral resources to fight the intruder. Knowing more about these early stages of pathogen recognition and response may provide scientists with crucial clues when it comes to preventing infections or treating inflammatory diseases resulting from overactive immunity.

When scientists looked for the very first "danger" signals emitted by a host infected with the parasite, they traced them not to an immune cell, as might have been expected, but to epithelial cells lining the intestines, where Cryptosporidium sets up shop during an infection. Known as enterocytes, these cells take up nutrients from the gut, and here they were shown to alert the body to danger via the molecular receptor NLRP6, which is a component of what's known as the inflammasome.

You can think about the inflammasome as an alarm system in a house.

Earlier researchers have focused on immune cells, like macrophages and dendritic cells, as being the first to detect foreign invaders, but this new finding underscores that cells not normally thought of as part of the immune system—in this case intestinal epithelial cells—are playing key roles in how how an immune response gets launched.

There is a growing body of literature that is really appreciating what epithelial cells are doing to help the immune system sense pathogens. They seem to be a first line of defense against infection.

Adam Sateriale el al., "The intestinal parasite Cryptosporidium is controlled by an enterocyte intrinsic inflammasome that depends on NLRP6," PNAS (2020). www.pnas.org/cgi/doi/10.1073/pnas.2007807118

https://medicalxpress.com/news/2020-12-gut-cells-alarm-parasites-in...

Comment by Dr. Krishna Kumari Challa on December 28, 2020 at 9:16am: Anti-diarrhea drug drives cancer cells to cell death

Scientists two years ago found evidence indicating that the anti-diarrhea drug loperamide could be used to induce cell death in glioblastoma cell lines. They have now deciphered its mechanism of action and, in doing so, are opening new avenues for the development of novel treatment strategies.

In certain types of tumor cells, administration of loperamide leads to a stress response in the endoplasmic reticulum (ER), the cell organelle responsible for key steps in protein synthesis in the body. The stress in the ER triggers its degradation, followed by self-destruction of the cells. This mechanism, known as autophagy-dependent cell death occurs when cells undergo hyperactivated autophagy. Normally, autophagy regulates normal metabolic processes and breaks down and recycles the valuable parts of damaged or superfluous cell components thus ensuring the cell's survival, for example in the case of nutrient deficiency. In certain tumor cells, however, hyperactivation of autophagy destroys so much cell material that they are no longer capable of surviving.

The loperamide-induced death of glioblastoma cells could help in the development of new therapeutic approaches for the treatment of this severe form of cancer.

Svenja Zielke et al, ATF4 links ER stress with reticulophagy in glioblastoma cells, Autophagy (2020). DOI: 10.1080/15548627.2020.1827780

https://medicalxpress.com/news/2020-12-anti-diarrhea-drug-cancer-ce...

Comment by Dr. Krishna Kumari Challa on December 28, 2020 at 8:43am: New SARS-CoV-2 neutralizing antibody enters clinical phase

Cologne University Hospital (UKK), University of Marburg (UMR), the German Center for Infection Research (DZIF) and Boehringer Ingelheim announced the initiation of Phase 1/2a clinical investigation of BI 767551, a new SARS-CoV-2 neutralizing antibody. By combining UKK, UMR and DZIFs expertise in virology, immunology and clinical investigation with Boehringer Ingelheims expertise in developing and manufacturing therapeutic antibodies, the partners developed BI 767551 as a potential new therapeutic and preventive/prophylactic option for fighting COVID-19. Virus neutralizing antibodies are expected to become an important line of defense against SARS-CoV-2, complementing vaccines and nonpharmaceutical interventions. They are being investigated as a therapy option for individuals with mild or severe infections, but also as prevention or prophylaxis in non-infected people with a high risk of infection or at risk .

Comment by Dr. Krishna Kumari Challa on December 28, 2020 at 7:29am: 10 times science made a sucky year suck less

Clapping seals, Great conjunction, COVID-19 vaccines, stink flirting...here's the amazing science of 2020.

https://www.livescience.com/10-times-science-made-sucky-year-suck-l...

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Top science and technology achievements of India in 2020

http://timesofindia.indiatimes.com/articleshow/79825076.cms?utm_sou...