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Comment by Dr. Krishna Kumari Challa on October 2, 2017 at 11:18am

A team in China has taken a new approach to fixing disease genes in human embryos. The researchers created cloned embryos with a genetic mutation for a potentially fatal blood disorder, and then precisely corrected the DNA to show how the condition might be prevented at the earliest stages of development.

The report, published on 23 September in Protein & Cell, is the latest in a series of experiments to edit genes in human embryos. And it employs an impressive series of innovations, scientists say. Rather than replacing entire sections of genes, the team, led by Junjiu Huang at Sun Yat-sen University in Guangzhou, China, tweaked individual DNA letters, or bases, using a precision gene-editing technology developed in the United States.

Liang, P. et al. Protein Cell https://doi.org/10.1007/s13238-017-0475–6 (2017)

Comment by Dr. Krishna Kumari Challa on October 1, 2017 at 10:54am

Quantum video chat links scientists

Ultrasecure quantum video chats are now possible across the globe.

In a demonstration of the world’s first intercontinental quantum link, scientists held a long-distance videoconference on September 29 between Austria and China. To secure the communication, a Chinese satellite distributed a quantum key, a secret string of numbers used to encrypt the video transmission so that no one could eavesdrop on the conversation. In the call, chemist Chunli Bai, president of the Chinese Academy of Sciences in Beijing, spoke with quantum physicist Anton Zeilinger, president of the Austrian Academy of Sciences in Vienna.

“It’s a huge achievement,” says quantum physicist Thomas Jennewein of the University of Waterloo in Canada, who was not involved with the project. “It’s a major step to show that this approach could be viable.”

Using a technique known as quantum key distribution, scientists share secret strings of numbers while ensuring that no eavesdroppers can intercept the code undetected. Those quantum keys are then used to encrypt information sent via traditional internet connections. Decoding the transmission requires the same key used for encryption, foiling would-be snoops.

- Science news.org

Comment by Dr. Krishna Kumari Challa on September 30, 2017 at 7:08am

Tropical forests have flipped from sponges to sources of carbon dioxide

The world’s tropical forests are exhaling — and it’s not a sigh of relief. Instead of soaking up climate-warming gases on balance, these so-called “lungs of the planet” are beginning to release them.

A new study based on analyses of satellite imagery of tropical Asia, Africa and the Americas suggests that tropical forests contribute more carbon dioxide to the atmosphere than they remove. Much of that carbon contribution is due to deforestation, the conversion of forests to urban spaces such as farms or roads. But more than two-thirds comes from a less visible source: a decline in the number and diversity of trees in remaining forests, researchers report online September 28 in Science.

Intact forests can be degraded or disturbed by selective logging, environmental change, wildfires or disease.

In total, the researchers found, tropical forests emit 862 teragrams of carbon to the atmosphere annually — more than all cars in the United States did in 2015 — and absorb only 436 teragrams of carbon each year. Of that net loss of carbon to the atmosphere, 69 percent is from degraded forests and the rest from deforestation.

Some 60 percent of those carbon emissions came from tropical America, including the Amazon Basin. Africa’s tropical forests were responsible for about 24 percent of the carbon loss, and Asia’s forests for 16 percent.

The results are a wake-up call that there is an opportunity for improvement.

Comment by Dr. Krishna Kumari Challa on September 23, 2017 at 11:36am

Comment by Dr. Krishna Kumari Challa on September 12, 2017 at 6:24am

Climate change threatens 33% of all parasites. Good news? Bad news, according to scientists! Read why...

Because parasites play an important part in our Eco-system!

The study published in the journal Science Advances was completed with the help of the U.S. National Parasite Collection, as well as specialized databases of ticks, fleas, bee mites, and feather mites. What's more, 17 researchers from eight countries spent years tracking down different parasite specimens in order to understand the species' habitat and needs.

By using climate forecasts to determine how the 457 parasite species will react to the changing climate, researchers found they are evidently among the most threatened life forms on Earth with regards to climate change, even more so than their hosts. In fact, models show that about a third of parasites could go extinct by 2070 from the effects of habitat loss alone, with the more conservative models showing instead a 5 to 10 percent loss.

Why is it bad?

Parasites don't often good reputations as they are often responsible for diseases and infections. By definition, parasites are organisms that live and thrive at the expense of its host. But did you know that they are also important members of the ecosystem?

As small as they are and despite their negative reputations, parasites actually contribute to keeping wildlife populations in check, and in providing a large percentage of food chain links. Many parasites have complex life cycles that require being passed from one host to another. Because of this, having strong populations of parasites are often indicators of a healthy ecosystem.

"It means the system has a diversity of animals in it and that conditions have been consistent long enough for these complex associations to develop," said Anna J. Phillips of the Smithsonian Institution's National Museum of Natural History. What's more, a wide range of parasites in an ecosystem means that they could compete with one another, therefore slowing down the spread of diseases. Without them, the ecosystem could be seriously affected.

Unfortunately, because of their bad reputation, they are often overlooked in studies regarding climate change and its impacts. It is only now that we see that they, too, are affected by the climate change. Because of the current study, scientists can look further into the implications of changing parasite populations. This is especially important as it could also lead to the thriving of other, possibly more invasive parasites as a result of the lack of competition.

Comment by Dr. Krishna Kumari Challa on September 6, 2017 at 11:06am

Indian uranium mine becomes dark matter lab

India’s very first uranium mine, the Jaduguda mine located in the state of Jharkhand, now hosts a laboratory for conducting experiments in fundamental physics.

The Jaduguda Underground Science Laboratory 550, built in a 37-square-meter cavern buried 905 metres and formerly used for storage, will focus on the search for dark matter. It was built by the Saha Institute of Nuclear Physics and it is expected to gather the country’s brightest experimental scientists interested in cutting-edge research.

Repurposing the cave in the 50-year-old mine managed by the Uranium Corporation of India required an initial investment of $32,000. Scientists considered this to be the best place to install a low-temperature cesium iodide detector because its depth would shield the device from other particles.

The site’s uranium deposits, which produce 25 per cent of the raw materials needed to fuel India’s nuclear reactors, are located some 300 metres away from the lab. Thus, physicists working there are not concerned about background radiation.

source.. mining.com

Comment by Dr. Krishna Kumari Challa on September 6, 2017 at 7:30am

New fluorescent dyes for advance biological imaging

Specific chemical building blocks in fluorescent molecules called rhodamines can generate nearly any color scientists desire - ROYGBIV and beyond, researchers report September 4, 2017 in the journal Nature Methods.

The work offers scientists a way to adjust the properties of existing dyes deliberately, making them bolder, brighter, and more cell-permeable too. Such an expanded palette of dyes could help researchers better illuminate the inner workings of cells.

The research team lit up cell nuclei, made larval fruit fly brains shine, and highlighted visual cortex neurons in mice that had tiny glass windows fitted into their skulls.

Jonathan B. Grimm, Anand K. Muthusamy, Yajie Liang, Timothy A. Brown, William C. Lemon, Ronak Patel, Rongwen Lu, John J. Macklin, Philip J. Keller, Na Ji, and Luke D. Lavis, "A general method to fine-tune fluorophores for live-cell and in vivo imaging," Nature Methods. Published online September 4, 2017. doi: 10.1038/nmeth.4403

Comment by Dr. Krishna Kumari Challa on August 28, 2017 at 8:58am

Updates in cancer research

Comment by Dr. Krishna Kumari Challa on August 25, 2017 at 7:31am

Comment by Dr. Krishna Kumari Challa on August 16, 2017 at 7:16am

India March for science, Hyderabad, Aug., 9th 2017

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